Simon Desiderio
@simon_desiderio
Followers
51
Following
176
Media
1
Statuses
35
Post-Doc @Dev_Gen_Lab, @ULBSciences Interested in the biology of sensory neurons
Joined December 2021
There is still time to join the #ISDN2024 programme! 🎉 Poster abstracts are welcomed for presentation alongside more than 40 fantastic speakers. View the programme, submit abstracts and book at: https://t.co/ikHXfWo5Gp Special rates available for trainees/Master’s students.
0
7
7
Happy to share the last preprint of the Bellefroid Lab 🇧🇪@Dev_Gen_Lab on sensory development! This time no Prdm12 in the title (but a bit in the content 👀). Congratulations to @TSzemes for the hard work and deeply grateful to @kristyredhorse for sharing invaluable mouse lines!
The temporal refinement of Dach1 is a key step in the functional maturation of primary somatosensory neurons https://t.co/WBcmgr6rj8
#bioRxiv
1
1
9
Registration is open for #ISDN2024! 🎉🎉 Special rates are available for trainees and Master’s students. Join our plenary speakers and participate in 10 symposia featuring more than 40 expert speakers. View the programme and register at: https://t.co/ikHXfWnxQR
0
8
15
#ISDN2024 Symposium: Cell type diversity from evo-devo perspectives. Join speakers Detlev Arendt @embl, Pawel Burkhardt @MSarsCentre, Maria Fernanda Ceriani @fundacionleloir, Eve Seuntjens @KU_Leuven and Sonia Sen @TIGS_India. Submit abstracts now at https://t.co/igIpBcV13X
5
5
14
Join us in Montpellier, France, 21-24 Sept 2024 for #ISDN2024 - the 25th Biennial Meeting of the International Society for #DevelopmentalNeuroscience. Abstract submission opening shortly - Sign up to mailing list here: https://t.co/rwrb3OFPGW
0
7
20
iScience - Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia. https://t.co/88ICoas1rT Check out our last paper led by former PhD candidate Dr. Simon Vermeiren, with @mayadannawi
@simon_desiderio
@AlbaSabateSJ
0
2
19
Congratulations to Frédéric Marmigère on his paper just accepted in eLife. We were very happy to contribute data to this nice study on Meis2 and touch...@SchwallerFred
https://t.co/5qJAVbESc3
0
3
9
Congratulations to Panagiotis Tsimpos, first author of this work!
0
0
2
To be quick, we observed that it is not the case. Nociceptors (and other somatosensory neurons) appear to develop just fine in the absence of G9a... Truth is to be found elsewhere! (5/5)
1
0
0
Previously, we ( https://t.co/x0Bcb6RPzD) and others demonstrated that KO of Prdm12 in mice results in agenesis of nociceptors. We thus speculated that if G9a is a critical component for Prdm12 function, G9a loss of function should recapitulate this phenotype. (4/5)
1
0
0
In this context, the histone methyltransferase G9a was suggested to mediate Prdm12 epigenetic function as both are able to interact with one another in vitro. (3/5)
1
0
0
Prdm12 is a transcriptional regulator whose mutation in humans results in congenital insensitivity to pain (CIP). However, it does not appear to bind DNA and has no enzymatic activity, suggesting it serves to bring together DNA binding proteins and functional cofactors. (2/5)
1
0
0
First preprint from the Bellefroid lab (@Dev_Gen_Lab)! We show that G9a is unlikely to mediate Prdm12 function during nociceptor development. (1/5)
Loss of G9a does not phenocopy the requirement for Prdm12 in the development of the nociceptive neuron lineage https://t.co/ZsNxdwZHju
#bioRxiv
1
2
3
Check out our latest Preprint. Great work from Sam @fluorescence_SC, We show that the mechanically gated ion channel Elkin1 is required for touch in mice! https://t.co/gxkz1dLsB0
biorxiv.org
The slightest touch to the skin initiates tactile perception that is almost immediate[1][1]. The extraordinary speed of touch perception is enabled by mechanically-activated ion channels, the opening...
1
18
79
In 2022 Silvia Arber, Martyn Goulding & Ole Kiehn were awarded the Brain Prize. To celebrate their achievements we organised a webinar series on motor control from leaders in the field. In case you missed it you can see them all here:
brainprize.org
Silvia Arber, Martyn Goulding, and Ole Kiehn have revolutionized our understanding of the fundamental cells and circuits underlying mammalian body movement and have defined the importance of these...
0
2
6
Congratulations for this straigthforward strategy! Very promising results!
0
0
3
This #FluorescenceFriday we are delighted to share our ‘Featured image’ from @simon_desiderio showing developing mouse dorsal root ganglia. Check out our post to find out how the image was acquired and about Simon’s research. https://t.co/qPuXL9okM7
0
2
6
Congratulations to Stefan Lechner on this lovely study. There is a long back story to why we made TMEM100 conditional knockout mice. But here Stefan and colleagues show that nociceptor sensitization does not always come from the periphery!
0
9
37
Excited to share my lab’s new paper out today @CellCellPress. "Touch neurons underlying dopaminergic pleasurable touch and sexual receptivity" Congratulations to this amazing team of scientists. https://t.co/VYf1nfkWtB
118
346
2K
Finally out! My PhD work supervised by the twitterless Dr. Cyril Rivat. Have you ever wondered whether the repetition of acute surgeries could lead to anxiodepression and chronic pain comorbidities? Answer is yes.
3
5
15