Sean Wilson
@sbwil91
Followers
280
Following
1K
Media
24
Statuses
258
From Melbourne, Aus. Studying kidney organoids in the Little group within reNEW at UCPH. Stem cells, organoids, transcriptomics, bioinformatics and microscopy.
Copenhagen, Denmark
Joined May 2013
Proud to announce publication of DevKidCC in @GenomeMedicine! The lockdown side-project that grew. DevKidCC robustly & reproducibly classifies kidney organoid #kidorg cells in #SingleCell datasets using ref-trained ML classifiers. https://t.co/mo2uHHvmGU Highlights:
link.springer.com
Genome Medicine - While single-cell transcriptional profiling has greatly increased our capacity to interrogate biology, accurate cell classification within and between datasets is a key challenge....
2
6
27
Starting to get very excited (and nervous!) for my talk at ISSCR in a few weeks! Presenting a short talk about our kidney assembloid protocol - check out our recent preprint for a sneak peek! https://t.co/BFuccMUMoN
#ISSCR2025 #kidneyorganoids
0
1
8
reNEW’s Annual Report 2024 is out. A little more than three years since our research collaboration across three nodes – @UCPH, in Denmark, @LUMC_Leiden in the Netherlands and @MCRI_for_kids in Australia – began, our collaborative work is yielding tangible results. reNEW now
0
3
2
Pleased to be sharing this chapter written with Nils @LindstromLab for Current Topics in Developmental Biology! Here we dive into how #nephrons establish proximal-distal patterning during #KidneyDevelopment & what this means for #StemCell-derived nephrons: https://t.co/sAXMLzl1Jh
0
4
9
We are hiring! Postdoctoral position available in the Little Group, Copenhagen University. We study kidney organoids using microscopy, transcriptomics, bioinformatics, bioengineering... all the fun stuff!!! https://t.co/xW8y9UMIha
0
3
5
Incredibly pleased to share our recent work on the development of iHSCs- a story that started before my time and it’s been an honour generating blue MLE mice. 🐁 🧫 congratulations to Elizabeth , Andrew, Ed and the labs! https://t.co/buTpMWkVEN Thread coming soon! 🧵
nature.com
Nature Biotechnology - Human hematopoietic cells derived from pluripotent cells repopulate multiple blood lineages in mice.
5
37
201
#JobAlert: Exciting PhD opportunity in reNEW Melbourne's Kidney Regeneration team with @JMVanslambrouck, based at @MCRI_for_kids. Join our team to develop stem cell-derived kidney tissue to better understand and treat chronic kidney disease. Apply now! https://t.co/wrEWOkibyY
renew.science
reNEW is transforming lives with cutting edge stem cell research. We use this knowledge to develop novel drugs and therapies to treat and cure diseases.
0
9
12
We are looking for a Student Assistant to help us implement #Diversity and Inclusion Initiatives @reNEW_Global . If you are interested and a student in the Copenhagen area apply before 20th of February! https://t.co/qvZm3qW3hm
@koebenhavns_uni @CBScph @lundbeckfonden @DTUtweet
candidate.hr-manager.net
0
11
12
PostDoc needed @reNEW_Global! Thanks to the @ERC_Research Starting Grant we are now looking for a talented postdoc to unravel how early mammalian development is coordinated. Apply: https://t.co/X1tL2abufm; Read more on research topic: https://t.co/gygH84y8MX
#Diversity #postdoc
1
87
124
.@reNEW_Global led by our Chief Scientist, Prof Melissa Little, has released its 1st #AnnualReport, highlighting the work accomplished by reNEW, a global consortium that focuses on translating #stemcell #science into therapies since its launch in 2022. 🔗➡️ https://t.co/RQCCpuXbeJ
0
9
12
How to build a mucociliary epithelium (MCE)? Lesson from frogs!🐸 Extremely happy to share our collaborative work with @kedar_natarajan lab, where we profiled developing Xenopus laevis MCE from pluripotent to specialized cell types by scRNAseq. 🧵(1/8): https://t.co/MlPq1IJftP
science.org
Single-cell analysis of mucociliary epithelium captures a cell-type and differentiation model, with insights for airway biology.
6
23
89
Super exciting news, congrats @kim_bak_jensen and all involved!
Innovation Fund Denmark grants millions to reNEW led research center StemScreen will operate thanks to grant a EUR 3.3 million from @Innofond. It's collaboration between researchers at @UCPH_health and the biotech firms, @Bioneer A/S and Synklino A/S. https://t.co/BsUvNTkwQx
0
0
2
I jumped on board to check it out and my oh my ChatGPT delivering the goods... honestly I am amazed #stemcells #organoids #ChatGPT
1
0
8
We have organoids!!! 🍒 on top of a great week. Superb effort from the team @inesmpsan & Jea to get #kidneyorganoid experiments going so rapidly! Excited for the next steps @reNEW_Global
1
1
26
It was amazing to be hosted by Cathelijne, @RabelinkT and the group 🤩. Thanks to everyone who came to the lecture & shared ideas/projects during my visit, felt very welcome!! #collaborativescience #kidneyorganoids
This week started with a beautiful example what reNEW has to offer for young researchers. Post-doc @sbwil91 started his career at MCRI, transferred to UCPH to start in a new group and was able to visit LUMC and learn from their experiences. Hopefully more examples will follow!
2
1
14
Great way to end the week, seeing our #stemcells start to differentiate towards #kidneyorganoids. With luck will have some nephron-filled blobs in a few weeks - and some pretty images! 🫰
2
1
40
First job done for the Copenhagen arm of the (Melissa) Little group - #stemcells in culture! Next up: #kidneyorganoids 🤩🫰#reNEW
3
1
45
See how @JMVanslambrouck and co (yes, I'm in there 😉) improved the PT in #stemcell derived #kidneyorganoids and used it to model covid infectivity. Beautiful science, congrats all!
Excited to share our new paper in @NatureComms: https://t.co/X7Dj4uYu85. We can make stem cell-derived kidneys (kidney organoids) with enhanced proximal tubules to benefit disease research and treatment in the future. @MCRI_for_kids @TheDohertyInst.
0
2
8
Thrilled to announce the publication of this research paper on NPHS2 variants and their impact on Podocin trafficking unraveling new insights on steroid-resistant nephrotic syndrome pathophysiology using iPSC-derived kidney organoids. @MCRI_for_kids #kidney #organoid #stemcells
One commonly mutated gene in steroid-resistant nephrotic syndrome is NPHS2. This study found that human kidney organoids created from missense variants of NPHS2 revealed reduced PODOCIN degradation and mistrafficking https://t.co/hCB4OIU9Ko
@kynanlawlor @Moinsaleem @Mithunbge
1
8
35
Thank you @HydraSchool for the most incredible week of intense #stemcell science delivered by world leading researchers. Not a bad choice of location either 😉!
0
2
19
Today I put this amazing gift frame of memories from my last 7 years at MCRI on my new desk at UCPH / reNEW... holy smokes it happened 🇦🇺➡️🇩🇰!! I'm here, in Copenhagen! So excited to keep science-ing here for team Little! #kidneyorganoids
0
1
38