Nils Lindstrom
@LindstromLab
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Studying how organs form & making artificial kidneys. Group leader at the Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research.
Joined February 2020
Organoids, Stem Cells, and Spatial Transcriptomics! Looking forward to building this with @GiorgiaQuadrato @MarianiLabUSC and @USCStemCell. Thanks to @CIRMnews and @KeckMedicineUSC for all the support! Job adverts going out soon!!
To democratize access to lab-grown organ-like structures known as organoids and other advanced stem cell and transcriptomic technologies, @USCStemCell will launch the CIRM ASCEND Center. @CIRMnews
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Kidney cells from stem cells. Yep, it's happening. Nils Lindström, PhD, of the @LindstromLab at @USCStemCell explains the process of turning stem cells into organoids, a pathway to identifying new treatments for kidney disease.
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Well done to MaryAnne Achieng who has made microscopy of organoids an artform.
How do you break symmetry along a cell planar axis? Of course WNT/BMP/FGF/NOTCH compete and talk. Each nephron is like an embryo patterning along its AP axis. @LindstromLab @USCStemCell
https://t.co/mUt83dBjMz
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How do you break symmetry along a cell planar axis? Of course WNT/BMP/FGF/NOTCH compete and talk. Each nephron is like an embryo patterning along its AP axis. @LindstromLab @USCStemCell
https://t.co/mUt83dBjMz
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How do you break symmetry along a cell planar axis? Of course WNT/BMP/FGF/NOTCH compete and talk. Each nephron is like an embryo patterning along its AP axis. @LindstromLab @USCStemCell
https://t.co/mUt83dBjMz
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Great to have the chance to discuss the future of kidney organoid technologies and the basis of kidney development & function with Jess @JMVanslambrouck Looking forward to more collaborations and insights to make next generation stem cell derived kidney models!
Pleased to be sharing this chapter written with Nils @LindstromLab for Current Topics in Developmental Biology! Here we dive into how #nephrons establish proximal-distal patterning during #KidneyDevelopment & what this means for #StemCell-derived nephrons: https://t.co/sAXMLzl1Jh
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Pleased to be sharing this chapter written with Nils @LindstromLab for Current Topics in Developmental Biology! Here we dive into how #nephrons establish proximal-distal patterning during #KidneyDevelopment & what this means for #StemCell-derived nephrons: https://t.co/sAXMLzl1Jh
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Check out Mark Corkins’ collaborative preprint with @AdRoMora from our lab and MaryAnne Achieng from @LindstromLab using comparative single-cell sequencing and in situ to create this beautiful spatial model of the developing adult frog kidney! https://t.co/rnhpY2DVUW
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The outer ear is a mammalian innovation but where did it come from? In our study in @Nature, @MathiThiru95 and colleagues find that the outer ear arose from modification of an ancestral gill program first originating in marine invertebrates. https://t.co/i05me2SXI4 1/n
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Such a great collaboration with @LeonardoMorsut and his team - am now certain that the way forward is through collaborations like these where devbio and synbio co-develop concepts. #wewillbuildakidney
tldr: we identify a new organizer activity in vivo in human developing kidney, noticed the lack of said organizing activity in kidney organoids and reconstituted the organizer action in vitro via synthetic organizers - longer thread on bluesky! @LindstromLab
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tldr: we identify a new organizer activity in vivo in human developing kidney, noticed the lack of said organizing activity in kidney organoids and reconstituted the organizer action in vitro via synthetic organizers - longer thread on bluesky! @LindstromLab
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Genes aren’t the sole driver instructing cells to build multicellular structures. In a paper in @NatureComms, @USCStemCell scientist @LeonardoMorsut and @Caltech computational biologist Matt Thomson characterize the influence of cell density. https://t.co/EA3H65nivC
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I am excited to share our work discovering neuro-endothelial cells (NECs) - a subtype of #endothelial cells that regulate #brain and #kidney blood flow and #immune balance - now available online! Movie: NECs (green) in the mouse motor cortex #vasculature. https://t.co/IvfxxpB9a7
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@Dev_journal @MarcellaBirtele For any neuroscience departments looking for junior faculty Marcella would be a terrific hire.
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How similar is kidney development in humans and in lab mice that form the foundation of basic medical research? In a new study published in @Dev_Cell, @USCStemCell scientists probe this question. @AndyMcMahonLab @LindstromLab @KeckSchool_USC
https://t.co/lA90DGlhHJ
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We have two 1-year positions with a 1-year renewal option available for clinical trainees interested in conducting research related to stem cell biology and/or regenerative medicine in one of the leading labs @USCStemCell. @KeckSchool_USC
https://t.co/DcoIjS40mC
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A new @USCStemCell study, led by Zhongwei Li's Lab (@LiLab_Kidney), introduces a new and improved way to grow the cells that give rise to the kidney’s filtration system. @AndyMcMahonLab @LindstromLab @ukrocharity @CellPressNews @NIH_CommonFund
stemcell.keck.usc.edu
In a new study published in Cell Stem Cell, USC scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney’s filtration system, the...
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Congratulations to all on this milestone paper from Zhongwei Li’s group! Self renewing nephron progenitors in a dish opens exciting avenues for kidney research!! https://t.co/umoISIWMlU
@USCStemCell
@LiLab_Kidney
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Celebrating #WorldKidneyDay with @ukrocharity and Zhongwei Li’s lab @USCStemCell and @KeckSchool_USC. @LiLab_Kidney and colleagues @AndyMcMahonLab, @LindstromLab and @JPetiPeterdi are progressing on generating a transplantable kidney from human stem cells to replace dialysis.
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To democratize access to lab-grown organ-like structures known as organoids and other advanced stem cell and transcriptomic technologies, @USCStemCell will launch the CIRM ASCEND Center. @CIRMnews
stemcell.keck.usc.edu
To democratize access to lab-grown organ-like structures known as organoids and other advanced stem cell and transcriptomic technologies, USC will launch the CIRM ASCEND Center, dedicated to “Advan...
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