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Simon Kohl Profile
Simon Kohl

@saakohl

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Founder at Latent Labs.

Joined December 2016
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@saakohl
Simon Kohl
3 months
Introducing Latent-X — our all-atom frontier AI model for protein binder design. State-of-the-art lab performance, widely accessible via the Latent Labs Platform. Free tier: https://t.co/NamdznPWjL Blog: https://t.co/2UkYDEe8a9 Technical report: https://t.co/0m2s3y7vwN
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@saakohl
Simon Kohl
8 days
Some excellent points here, which I always felt applied to why AlphaFold generalizes so well. AF2 is so accurate on unseen proteins because it's trained to decode the MSA - which acts like a lossy 'memory' of the structure. Its architecture pre-bakes geometric principles that
@karpathy
Andrej Karpathy
10 days
My pleasure to come on Dwarkesh last week, I thought the questions and conversation were really good. I re-watched the pod just now too. First of all, yes I know, and I'm sorry that I speak so fast :). It's to my detriment because sometimes my speaking thread out-executes my
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@saakohl
Simon Kohl
17 days
Honoured to join Prime Minister @Keir_Starmer and Secretary of State for Business and Trade @peterkyle on the UK's business visit to India this week. My first trip to India, and what a visit! Proud to join the delegation, traveling alongside Britain’s leading companies to
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@saakohl
Simon Kohl
1 month
Last night @nvidia CEO Jensen Huang announced $2B of investments in UK AI start-ups, including in @Latent_Labs. Not the only ace up his sleeve, Jensen also had Prime Minister @Keir_Starmer join on stage for the occasion. Pinched myself this morning, but it did happen, caught
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@saakohl
Simon Kohl
1 month
Honored to have been nominated 35th in the @observer's A.I. Power Index 2025 of 100! Truly humbling to be part of this star-studded list. @demishassabis, @DarioAmodei, @JeffDean, @matistanis - all folks that I have admired (and now had the privilege to work with) in ML and
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@Latent_Labs
Latent Labs
1 month
Our very own @SeBayesian and @SimMat20 will present at In Silico, London, on 1 October. We'll be speaking about Latent-X, our Atom-level Frontier Model for De Novo Protein Binder Design. Also featuring @amyxlu and @DominiqueLaLo, we're looking forward to it! Register for In
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luma.com
Recent advancements in computation are transforming the biomolecular sciences - from fine simulations of molecular structure and drug discovery, to…
@dmmiller597
David Miller
1 month
In Silico is back for round #002. Come see great talks on the future of protein and molecular design from @amyxlu @SimMat20 @SeBayesian and @DominiqueLaLo. October 1st 6pm at @IDEALondon https://t.co/a1XsCKhamO
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@saakohl
Simon Kohl
1 month
We're working with @nvidia to accelerate computational drug discovery. See how they are working with us and the broader UK AI ecosystem in the press release below, issued as part of the UK state visit. 🇺🇸🇬🇧
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@saakohl
Simon Kohl
2 months
Really cool to see @nanome_inc review Latent-X in their VR environment! 💻🧬 They pick an unseen target, and find the @Latent_Labs platform generates diverse binders with highly specific biochemical interactions! 💯 Watch their discussion of the designs here:
lnkd.in
This link will take you to a page that’s not on LinkedIn
@nanome_inc
Nanome
2 months
Beta sheet barrel or alpha helix coil—which binder would you trust? We tested Latent Labs’ designs in Nanome VR. See the full exploration on YouTube.
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@saakohl
Simon Kohl
2 months
We work with AWS to enable our partners with our frontier AI models. Right where they need them, whether that’s in our platform or deployed in their virtual private containers. Our platform let’s our users generate protein binders at the push of a button. In a free tier, open to
@AWSstartups
AWS Startups
2 months
🧬@Latent_Labs has a vision of “computational mastery of biology,” using #AWS solutions & #generativeAI to make the science “programmable.” Discover how: 👉 https://t.co/UfzqTWH3IC
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@saakohl
Simon Kohl
3 months
It's been great to talk to @TomMackenzieTV of @Bloomberg News about the launch of our protein design model and platform this morning!
@Latent_Labs
Latent Labs
3 months
Latent-X has been available for a little over two weeks, and we couldn't be more excited about the science that is already being done with it on our platform. Our CEO @saakohl joined @Bloomberg News Daybreak Europe this morning to talk about why we're building it, and the impact
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@radicalvcfund
Radical Ventures
3 months
In this week's #RadicalReads, @saakohl, Founder and CEO of @Latent_Labs, explores how the recently launched Latent-X model is making biology programmable by enabling scientists to design novel proteins with atomic precision directly in their browser:
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radical.vc
Radical portfolio company Latent Labs has launched Latent-X, a web-accessible AI model that enables scientists to design novel proteins.
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@Latent_Labs
Latent Labs
3 months
Thank you @decodingbio for covering our launch and reviewing our platform on binder design tasks! The authors concluded: 'Latent Lab’s new platform speaks for itself.' Read the full review article here:
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@Latent_Labs
Latent Labs
3 months
Showcasing Latent-X's breakthrough macrocycle designs. Our AI achieved an unprecedented 91-100% hit rate with single-digit micromolar binding affinities—functional binders on every single target tested. Explore our binders without logging in: https://t.co/y3rt7xJ9AP
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@saakohl
Simon Kohl
3 months
It's been a fantastic first few days of public usage of the Latent Platform! The team has been providing white glove user support - for feedback or requests, you can reach us through our feedback channels: https://t.co/zmz4fnXas1 Also, check out our sharing feature below: You
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@Latent_Labs
Latent Labs
3 months
The first 3 days have been incredible. The response from our research community has been phenomenal. Many hundreds of users, tens of thousands of designs and amazing feedback flowing in.
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@Latent_Labs
Latent Labs
3 months
🧬 Latent-X is our first frontier model for protein design. For mini-binders, our AI model achieved picomolar binding affinities — the strongest reported vs prior methods in head-to-head lab validation. Explore our best binders here (no login required): https://t.co/foSS9ICdyX
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@Latent_Labs
Latent Labs
3 months
‘Latent Labs launches web-based AI model to democratize protein design.’ Thank you @TechCrunch and @MTemkin for the coverage. Read the full story:
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techcrunch.com
The company claims that its model achieved state of the art on specific metrics.
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@ArdaGoreci
Arda Göreci
3 months
It is amazing that bench scientists are being given superpowers through computational tools like Latent-X! Huge congrats to the team!!
@saakohl
Simon Kohl
3 months
Introducing Latent-X — our all-atom frontier AI model for protein binder design. State-of-the-art lab performance, widely accessible via the Latent Labs Platform. Free tier: https://t.co/NamdznPWjL Blog: https://t.co/2UkYDEe8a9 Technical report: https://t.co/0m2s3y7vwN
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@matistanis
Mati Staniszewski
3 months
@saakohl Congratulations - that’s amazing!
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@radicalvcfund
Radical Ventures
3 months
Radical portfolio company @Latent_Labs unveils Latent-X, their frontier AI model. Co-founded by AlphaFold pioneer @saakohl, Latent Labs is making biology "programmable" to accelerate drug discovery. Learn more about Latent-X here:
latentlabs.com
@Latent_Labs
Latent Labs
3 months
5 months from funding to shipping our first frontier model. Latent-X achieves state-of-the-art hit rates for macrocycles and mini-binders, with picomolar binding affinities — a breakthrough in de novo protein binder design. Available now on our no-code platform!
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@AvivSpinner
Aviv Spinner
3 months
I love the trend of companies publishing technical reports / blogs instead of spending a year+ in peer review publishing detention - get your research OUT THERE!!!! v excited to read
@saakohl
Simon Kohl
3 months
Introducing Latent-X — our all-atom frontier AI model for protein binder design. State-of-the-art lab performance, widely accessible via the Latent Labs Platform. Free tier: https://t.co/NamdznPWjL Blog: https://t.co/2UkYDEe8a9 Technical report: https://t.co/0m2s3y7vwN
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@inovia
Inovia Capital
3 months
🚀 Big milestone — impressive science and great to see it made so accessible. Congrats to the @Latent_Labs team!
@saakohl
Simon Kohl
3 months
Introducing Latent-X — our all-atom frontier AI model for protein binder design. State-of-the-art lab performance, widely accessible via the Latent Labs Platform. Free tier: https://t.co/NamdznPWjL Blog: https://t.co/2UkYDEe8a9 Technical report: https://t.co/0m2s3y7vwN
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