Raúl Padrón
@raulpadron
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Curiosity-driven research rules! Muscle Structural Biologist, Professor. UMass Chan Medical School, Division of Cell Biology and Imaging, Padrón-Craig Lab.
Worcester, MA
Joined September 2009
Our paper is now in @Nature: #CryoEM 6 Å reconstruction of #human cardiac thick filament C-zone in #mavacamten, showing #myosin heads, tails, #titin, #MyBP-C. Many implications for a 60-year mystery on #cardiac #muscle #physiology, #structure and #disease.
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RT @UMassChan: How can you not smile at this photo of one Nobel Laureate from @UMassChan, Craig C. Mello, PhD, taking a selfie with another….
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RT @UMassChan: Learn about UMass Chan Medical School’s newest Nobel Laureate, Victor R. Ambros, PhD: This morning,….
umassmed.edu
Internationally renowned geneticist and pioneer of microRNA, Victor R. Ambros, PhD, who will share the 2024 Nobel Prize in Physiology or Medicine for his co-discovery of microRNA, is the Silverman...
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RT @Nature: This week in Nature: Beat generation - molecular structure of the myosin filaments that power the heart. Browse the full issue:….
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RT @ShawPrize: “While science can be a challenge… All that pales in comparison to the thrill of the questions to be asked, of seeing them a….
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RT @NatureNV: Thick filaments help the heart to beat. Peter Knight @AstburyCentre @ScienceLeeds discusses structural evidence that provid….
nature.com
Nature - Cryo-electron microscopy reveals the structure of muscle thick filaments.
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RT @NatRevCardiol: Two papers in @Nature describe the structure and conformation of myosin in the cardiac thick filaments and how it intera….
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RT @JulienPaganin: Really proud to share our last preprint on Omecamtiv and Mavacamten, two modulators of cardiac myosin. Years in the maki….
biorxiv.org
Inherited cardiomyopathies are amongst the most common cardiac diseases worldwide, leading in the late-stage to heart failure and death. The most promising treatments against these diseases are...
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RT @CampbellLabatUK: Excited to have played a small part in this amazing study in @nature by Drs. Dutta, Nguyen, Padron, and Craig from @UM….
uknow.uky.edu
Kenneth S. Campbell, Ph.D., and fellow researchers have produced single-particle 3D reconstructions of a microscopic part of the heart. To put that level into perspective, if the heart is a contine...
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RT @Nature: Nature research paper: Structure of the native myosin filament in the relaxed cardiac sarcomere
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RT @Nature: Thick filaments help the heart to beat. Peter Knight @AstburyCentre @ScienceLeeds discusses structural evidence that provides….
nature.com
Nature - Cryo-electron microscopy reveals the structure of muscle thick filaments.
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The @UMass Chan Padron-Craig lab PDB 8G4L atomic structure was achieved at the @UMass Chan Cryo-EM Core, superbly staffed and equipped (@thermofisher Titan Krios, Talos-Arctica, Glacios), providing excellent hands-on training.
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Our paper now acepted in Nature!.
Excited for our new #CryoEM reconstruction of #human cardiac thick filament C-zone in #mavacamten, showing #myosin heads, tails, #titin and #MyBP-C at 6 Å resolution. Many implications for #cardiac #muscle #physiology, #structure and #disease.
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RT @SOBLA_BIOF: 🎉🎉🎉Congratulations to Dr. Eduardo Perozo 🇻🇪🇺🇸 (@eperozo_), Professor @UChicago and @SOBLA_BIOF member, newly elected member….
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RT @Planaria1: A labor of love. “The reconstruction resolves past uncertainties & integrates previous data on cardiac muscle structure & fu….
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Excited for our new #CryoEM reconstruction of #human cardiac thick filament C-zone in #mavacamten, showing #myosin heads, tails, #titin and #MyBP-C at 6 Å resolution. Many implications for #cardiac #muscle #physiology, #structure and #disease.
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