Dr Steven Quay
@quay_dr
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Physician-Scientist Best Selling Author
Joined May 2020
$ATOS is streamlining our EVANGELINE Phase 2 trial for (Z)-endoxifen in breast #cancer to maximize efficiency. This focused design cuts costs, accelerates objective readouts, and extends our runway. We’re exercising financial discipline and zeroing in on NDA-enabling work for
#AtossaTherapeutics announces an amendment to its Phase 2 EVANGELINE study of (Z)-endoxifen in premenopausal women with newly diagnosed early-stage ER+/HER2- #breastcancer. Read more: https://t.co/xGT3uGBO4g
#BreastCancerAwareness #ThinkPink $ATOS #BreastCancerAwarenessMonth
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Screening finds suspicion; diagnosis needs proof. ACA covers the first (mammograms), but many plans still bill for the second (ultrasound/MRI). The Breast Imaging Coverage Act closes that gap. ~50% of women have dense breasts—early detection shouldn’t depend on a copay.
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Hey, New York — Brian thinks he's our new CFO. We gave him a stage to prove it.
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Day 10 — New frontiers: Endoxifen trials Clinical trials are the engine of truth. Ours ask a simple question: does targeted Endoxifen exposure translate into clinically meaningful outcomes? Follow the data with us: https://t.co/PFzWVTO5vn $ATOS @atossainc
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Thank you @PRDaily for naming me a 2025 finalist. Science advances when we explain it well, without drama and without spin. I’m proud to keep the message focused on what counts: giving people the best analysis of health-related stories. Learn more: https://t.co/XpjUBZKItu
ragan.com
As the communications landscape continues to evolve at a breakneck pace, the PR community has once again risen to the challenge, bringing fresh thinking, strategic agility and creative tenacity to...
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Day 9 — Why some don’t respond to tamoxifen Genetics (e.g., CYP2D6), drug interactions, and PK variability can blunt Endoxifen levels from tamoxifen. Direct Endoxifen is being studied to address variability head-on. Investigational; not approved. $ATOS
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$BTC We called the September bottom and this drop, stop missing out
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Is it simply a business dinner when you get together with the team that helped $ATOS go public years ago and are now the core of our IR team? Talking about our families, our pets, and yes, the bright @atossainc future. @CoreIR_ is on the job!
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Day 8 — Estrogen receptors 101 ER is a switch. Turn it down, tumors slow. Precision is the goal: right patient, right exposure, right duration. That’s the future we’re working toward at $ATOS. #BreastCancerAwarenessMonth @atossainc
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Without the exceptional work of the @AmericanCancer Society, @Breastcancerorg, @LivingBeyondBC, the @NBCF, @SusanGKomen, and so many more, #BreastCancerAwareness would not be where it is today. A big THANK YOU from the $ATOS team! #PinkOctober #ThinkPink #BCAM #BreastCancer
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Day 7 — 2025 by the numbers Incidence up in some cohorts; mortality trending down with earlier detection and better therapies. Data remind us: progress is real, but unfinished. That’s why we’re building. $ATOS #BreastCancerAwarenessMonth @atossainc
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Congrats to Mary Brunkow, Fred Ramsdell & Shimon Sakaguchi on today’s #NobelPrize. Their regulatory T-cell/FOXP3 discoveries don’t just explainn autoimmunity — they matter in breast cancer: Tregs shape immune escape, and FOXP3. https://t.co/q0JeTt4bGN
nobelprize.org
The Nobel Prize in Physiology or Medicine 2025 was awarded jointly to Mary E. Brunkow, Frederick J. Ramsdell and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance"
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Day 6 — How tamoxifen works; where Endoxifen fits Tamoxifen blocks ER signaling; Endoxifen is the metabolite that does much of that work. Direct Endoxifen aims for consistent exposure across patients, an idea we’re testing carefully. Investigational; not approved. $ATOS
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Day 5 — Princess Atossa’s lesson Herodotus wrote of Princess Atossa, history’s first recorded #breastcancer patient. Her story is our namesake, and our motivation to push the science forward with rigor and humility. $ATOS #BreastCancerAwarenessMonth @atossainc #ThinkPink
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https://t.co/4PFF1LTlQ4 This is a study of women who missed their first mammogram and then subsequently died of breast Cancer at a higher rate. Where and when would you like to debate?
bmj.com
Objective To determine whether women who did not attend their first mammography screening invitation have a long term risk of poor screening adherence and breast cancer outcomes. Design Population...
Do you accept a debate on the evidence that mammography screening causes almost as many cancers as it detects? https://t.co/lGEGxbVieR
#BreastCancerAwarenessMonth
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As for the velocity... You do know that all electromagnetic radiation moves at the same speed, regardless of the amount of energy? That would be the speed of light... Maybe you should learn some basic high school physics before you try to keep women from getting mammographs.
@quay_dr @atossainc Ionizing radiation is carcinogenic This fact is not in dispute We have been told by ppl like you,that screening mammography is safe because it’s “ low dose” ionizing radiation What we were NOT told is that the ionizing radiation is delivered at a high velocity- and is indeed
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A mammogram produces about 0.4 mSev radiation. We naturally receive 3.0 mSev per year from just living; the sun, soil, water. The dose is 7 weeks of just living. Screening mammograms save lives. Happy to debate you to reach women with facts so they can make informed decisions.
@quay_dr @atossainc Ionizing radiation is carcinogenic This fact is not in dispute We have been told by ppl like you,that screening mammography is safe because it’s “ low dose” ionizing radiation What we were NOT told is that the ionizing radiation is delivered at a high velocity- and is indeed
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Day 4 — Mammograms still matter Mammography isn’t perfect, but it’s the workhorse of early detection. Please, get screened on schedule. Science advances fastest when detection and treatment move together. $ATOS #BreastCancerAwarenessMonth @atossainc #BreastCancer #ThinkPink
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In my opinion this is a, way in the future, possible problem. Until we can actually make life in the lab that is not mirror the only slightly harder mirror life problem can be addressed. With natural life, you can have every protein, lipid, sugar, and complete genetic code.
"[M]irror bacteria could present two main dangers. First, they could evade...immune systems..., causing pandemics that could kill people and animals and devastate crops. Second, mirror bacteria could evade predators that keep...natural bacteria in check" https://t.co/rAGn9gKC8Z
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My father, LaGene Quay (1927-1997), was a chemistry and physics teacher. My earliest memories were going to his high school laboratory on a Saturday and helping set up the experiments for the next week. My love of science was born there.
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Day 3 — What is Endoxifen? Tamoxifen is a pro-drug. Endoxifen is its active metabolite with stronger ER-binding and anti-estrogen effects. We’re studying direct Endoxifen dosing to target exposure, not just pill size. Investigational; not approved.
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