PrecisionLife
@precisionlifeAI
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PrecisionLife is the clinical-stage precision medicine company for complex chronic diseases. Creating better, more personalized treatment options for patients.
Oxford, UK | Cambridge, MA
Joined January 2014
These results confirm that #ME is a deeply polygenic & biologically heterogeneous condition with @ least 4 major disease mechanisms implicated by genetic signals Neurological dysregulation๐ง Inflammation๐ฅ Cellular stress responseโ ๏ธ Calcium signalling๐ฅ https://t.co/4022Ht3jlJ
precisionlife.com
Groundbreaking ME study identifies 250+ genes, links with long COVID, and uncovers new drug repurposing opportunities to advance targeted treatments
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WEBINAR TODAY: Our researchers are unpacking the new ME genetics study today - join the live webinar to hear the findings first-hand and get your questions answered. ๐
Today ๐ 2PM GMT ๐ Register: https://t.co/JyMcGneEBb
#pwME #MECFS #longCOVID #MissingMillions
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Our genetic analysis of ME is now live. The new study identifies 250+ core ME genes, shared biology with long COVID, and dozens of drug repurposing opportunities for precision trials. Huge thanks to our partners and the @DecodeMEstudy participants. #pwME #longCOVID #MECFS
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Weโre excited to share a recently release preprint from our collaborative work with @PrecisionLife - identifying and validating 75 novel genes associated with endometriosis. #Endometriosis #PatientsCantWait
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โถ๏ธ Watch in full here: https://t.co/MdyLmY1NJp. Thank you to the community for your ongoing strength โ your voices and experiences are driving science forward. #SevereMEDay #MECFS #LongCOVID #PrecisionMedicine #Genomics #ClinicalTrials #DrugRepurposing #MyalgicE
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๐ฅ As part of todayโs recognition of #SevereME, weโre sharing this recent presentation by our Co-founder, Rowan Gardner, given at International ME Conference: ๐ฃ๐ฟ๐ฒ๐ฐ๐ถ๐๐ถ๐ผ๐ป ๐๐ถ๐ฎ๐ด๐ป๐ผ๐๐๐ถ๐ฐ ๐ง๐ฒ๐๐๐ ๐ฎ๐ป๐ฑ ๐ฃ๐ฒ๐ฟ๐๐ผ๐ป๐ฎ๐น๐ถ๐๐ฒ๐ฑ ๐ง๐ฟ๐ฒ๐ฎ๐๐บ๐ฒ๐ป๐๐ ๐ณ๐ผ๐ฟ ๐ ๐.
๐ง๐ผ๐ฑ๐ฎ๐ ๐ถ๐ ๐ฆ๐ฒ๐๐ฒ๐ฟ๐ฒ ๐ ๐ ๐๐ฎ๐ โ a moment to acknowledge the strength, resilience, and determination of those living with the most debilitating forms of Myalgic Encephalomyelitis.
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We are now running ๐ฐ๐น๐ถ๐ป๐ถ๐ฐ๐ฎ๐น ๐๐ฟ๐ถ๐ฎ๐น๐ ๐ถ๐ป ๐๐ต๐ฒ ๐จ๐ฆ to validate new non-invasive diagnostic and therapeutic options โ a major step toward faster diagnosis, targeted care, and hope for millions of patients.
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Thanks to you, weโve: โ๏ธ Confirmed the ๐ณ๐ถ๐ฟ๐๐-๐ฒ๐๐ฒ๐ฟ ๐ด๐ฒ๐ป๐ฒ๐๐ถ๐ฐ ๐ฒ๐๐ถ๐ฑ๐ฒ๐ป๐ฐ๐ฒ for ME/CFS and long COVID โ๏ธ Identified ๐๐ต๐ฎ๐ฟ๐ฒ๐ฑ ๐ฑ๐ถ๐๐ฒ๐ฎ๐๐ฒ ๐บ๐ฒ๐ฐ๐ต๐ฎ๐ป๐ถ๐๐บ๐ between both conditions โ๏ธ Discovered genes that ๐ฟ๐ฒ๐๐ถ๐๐ ๐ฎ๐ป๐ฑ ๐ฝ๐ฟ๐ผ๐๐ฒ๐ฐ๐ against ME
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We are deeply grateful to the ME community whose participation in research has enabled ground-breaking progress in understanding this long-neglected condition so that new diagnostic tools and drug treatment can be developed with greater clarity.
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๐ง๐ผ๐ฑ๐ฎ๐ ๐ถ๐ ๐ฆ๐ฒ๐๐ฒ๐ฟ๐ฒ ๐ ๐ ๐๐ฎ๐ โ a moment to acknowledge the strength, resilience, and determination of those living with the most debilitating forms of Myalgic Encephalomyelitis.
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Millions are still waiting for answers. Ahead of #SevereMEAwarenessDay, weโre reaffirming our support and using genetic insights to develop the first non-invasive mechanostic tests to accelerate diagnosis and improve care. ๐ https://t.co/xBA9VITLxl
#MECFS #LongCOVID
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On this Global MND Awareness Day, we're sharing our latest work uncovering the mechanisms behind ALS, new protective biology, and a path to non-invasive, personalized diagnosis and treatment. Read more: https://t.co/GW3Tpc1yVf
#ALS #MND
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โฐ Last chance to register! Our webinar on #MECFS & #LongCOVID is tomorrow. Join for the latest research insights and their implications for the prediction, treatment and prevention of the conditions. ๐ Register: https://t.co/hMsPJjnawx
#pwME #MyalgicE #MillionsMissing
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Join the free webinar hosted by @actionforme on 6 June to hear the latest genetic research on ME/CFS & Long COVID and what it means for patients, clinical practice, and the future of precision medicine. ๐ https://t.co/hMsPJjnawx
#MECFS #LongCOVID
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๐ฅ ๐๐
๐ฝ๐ฒ๐ฟ๐ ๐ฃ๐ฟ๐ฒ๐๐ฒ๐ป๐๐ฎ๐๐ถ๐ผ๐ป: We highly recommend watching Dr. Sayoni Das' presentation, #PrecisionMedicine for Long COVID and ME/CFS. ๐ ๐ช๐ฎ๐๐ฐ๐ต ๐ต๐ฒ๐ฟ๐ฒ:
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๐๐ฒ๐ป๐ฒ๐๐ถ๐ฐ ๐ฅ๐ถ๐๐ธ ๐๐ฎ๐ฐ๐๐ผ๐ฟ๐ ๐ณ๐ผ๐ฟ ๐ฆ๐ฒ๐๐ฒ๐ฟ๐ฒ ๐ฎ๐ป๐ฑ ๐๐ฎ๐๐ถ๐ด๐๐ฒ ๐๐ผ๐บ๐ถ๐ป๐ฎ๐ป๐ #๐๐ผ๐ป๐ด๐๐ข๐ฉ๐๐ ๐ฎ๐ป๐ฑ ๐๐ผ๐บ๐บ๐ผ๐ป๐ฎ๐น๐ถ๐๐ถ๐ฒ๐ ๐๐ถ๐๐ต #๐ ๐๐๐๐ฆ: 73 novel genes associated with Long COVID, and shared mechanisms with ME/CFS https://t.co/gRxCmJrwt6
link.springer.com
Journal of Translational Medicine - Long COVID is a debilitating chronic condition that has affected over 100 million people globally. It is characterized by a diverse array of symptoms, including...
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๐ ๐ฅ๐ฒ๐๐ฒ๐ฎ๐ฟ๐ฐ๐ต ๐๐ถ๐ด๐ต๐น๐ถ๐ด๐ต๐๐: ๐๐ฒ๐ป๐ฒ๐๐ถ๐ฐ ๐ฅ๐ถ๐๐ธ ๐๐ฎ๐ฐ๐๐ผ๐ฟ๐ ๐ณ๐ผ๐ฟ #๐ ๐๐๐๐ฆ ๐๐ฑ๐ฒ๐ป๐๐ถ๐ณ๐ถ๐ฒ๐ฑ ๐๐๐ถ๐ป๐ด ๐๐ผ๐บ๐ฏ๐ถ๐ป๐ฎ๐๐ผ๐ฟ๐ถ๐ฎ๐น ๐๐ป๐ฎ๐น๐๐๐ถ๐: 14 novel genetic associations, paving the way for precision medicine. https://t.co/By1g0CWqos
link.springer.com
Journal of Translational Medicine - Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic disease that lacks known pathogenesis, distinctive diagnostic criteria, and...
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Through our innovative AI-led combinatorial analytics platform, we've identified the first reproducible genetic associations for these complex conditions, offering hope for millions affected worldwide.
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๐ฌ ๐ ๐ ๐๐๐ฎ๐ฟ๐ฒ๐ป๐ฒ๐๐ ๐ช๐ฒ๐ฒ๐ธ ๐ฆ๐ฝ๐ผ๐๐น๐ถ๐ด๐ต๐: ๐ฃ๐ถ๐ผ๐ป๐ฒ๐ฒ๐ฟ๐ถ๐ป๐ด ๐ฅ๐ฒ๐๐ฒ๐ฎ๐ฟ๐ฐ๐ต ๐ถ๐ป ๐ ๐/๐๐๐ฆ ๐ฎ๐ป๐ฑ ๐๐ผ๐ป๐ด ๐๐ข๐ฉ๐๐ This #MEAwarenessWeek, we're proud to share our progress in understanding and treating #MECFS and #LongCOVID. ๐ https://t.co/kjlM3aU6ic
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Among 491 patients with #SevereME: 13% had gastrostomy 17% were tube fed 20% could sometimes eat 37% had nausea hindering eating 50% had stomach pains when eating 43% had problems swallowing. #MEAwarenessWeek
#EndMalnutritionInME
https://t.co/UlhQYTIOmi
mdpi.com
There is a striking lack of systematic knowledge regarding the symptom burden, capacity for activities of daily living, and supportive measures for the most severely ill ME/CFS patients. The present...
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