CONFERENCES | A total of 5 @iibm_uc @ibiochile @ucatolica PhD students participated in the international 39º Annual Meeting of The @ProteinSociety — a record attendance for our lab 🎉 (1/5)

RT @MoAlQuraishi: RosettaFold 3 is out!

What do you want to know?.

We would like to thank The @ProteinSociety and @EMBO for allowing our attendance to present research on plastic-degrading enzymes and fold-switching proteins, funded by @HomeworldBio, @ICGEB, @ANID_Chile, @min_ciencia and @NLHPC (5/5).

The surprise happened during the awards ceremony, with @Cyndi_TA receiving one of the @ProteinSociety awards for best presentation by graduate students! An exceptional accomplishment of great importance for @iibm_uc @ibiochile @ucatolica @ANID_Chile (4/5)

Then, all @iibm_uc @ibiochile @ucatolica PhD students (@afgrinen, @Cyndi_TA, @JorgeFGonzalez, @Camiproline & Vale Eltit) attending the Annual Symposium of The @ProteinSociety presented their @ICGEB @HomeworldBio @ANID_Chile funded work in poster sessions during the week (3/5)

First, @Cyndi_TA, PhD student from @iibm_uc @ibiochile @ucatolica, kicked off our participation by presenting a flash talk on the ancestral sequence reconstruction of RfaH, funded by @ANID_Chile, during the 39 Annual Symposium of The @ProteinSociety #PS39 (2/5)

CONFERENCES | On Feb 2025, @iibm_uc PhD student @afgrinen gave a fantastic talk on the design of novel PET-degrading enzymes using deep learning, in collaboration with @AI_Proteins, during the 2025 edition of Winter RosettaCon from @RosettaCommons in Boston

CONFERENCES | On October 2024, @AmadaCamps, Valeria Eltit, @Roci_gp, @cxarramirez and former PhD student @PBlazq_San participated with poster presentations and short talks in the 2nd Carbios International Conference on enzymatic recycling of plastics held in Toulouse, France.

A fantastic way to start our new FONDECYT Grant @ANID_Chile @min_ciencia and another excellent collaborative research being released by our lab at @iibm_uc @ibiochile @ucatolica (5/5).

This work was led by @iibm_uc @ibiochile PhD student @JorgeFGonzalezH and by @MFreiberge, in collaboration with @DavisonGalaz from @CBSM_UTalca, and is a continuation of our work in frustration between our PI @cxarramirez and @GonzaParra_ from @BSC_CNS (4/5).

This combination of simplified MD simulations and frustration analysis could be useful for determining key residues involved in the fold-switch of other metamorphic proteins (3/5).

By combining fold-switch simulations generated using structure-based models and contact-level frustration analysis of these trajectories, we identified 20 key residues involved in the fold-switch of RfaH, many of which have been experimentally validated. (2/5).

NEW ARTICLE | Our work on using frustration to understand the key residues driving the fold-switch of RfaH is now out on Protein Science @ProteinSociety 🎉 (1/5).

RT @iibm_uc: Felicitamos a nuestro académico Andrea Ravasio, quién forma parte del nuevo proyecto SELFO Núcleo Milenio .

AWARDS | Congratulations to Natalia (@NRodriguezBin), undergrad student from our lab @iibm_uc @ibiochile, for winning one of the three awards for Best Poster Presentation at the @conesul2024 conference in Buenos Aires, Argentina 🎉

In this @conesul2024 adventure, we are joined by Felipe (@fengel97), Luisa & Jens Meiler @MeilerLab! They went to Chile to deliver a @RosettaCommons workshop at the beginning of this week, and Jens presented today in Argentina about the future of protein/chemical design using AI.

Domi, Javi (@AmadaCamps) and Naty, students from our lab @iibm_uc @ibiochile @ucatolica are now attending the @conesul2024 conference in Buenos Aires, alongside @cxarramirez (1/2).

Thanks to @RosettaCommons @MeilerLab @iibm_uc @dccuc @ucatolica for sponsoring this workshop! (3/3).

Slots for attending the lectures and hands-on workshop, which will be taught by @fengel97 and Luisa Krämer from @UniLeipzig, are VERY LIMITED and will be available on a FIRST COME FIRST SERVE BASIS. You can register in the following Google Forms:.(2/3).

WORKSHOP | We are organizing a short seminar/workshop on the use of the Rosetta software, the BioChemical Library, and AI-enabled protein structure prediction tools at @iibm_uc (1/3). Our main guest in Prof. Jens Meiler @MeilerLab from @UniLeipzig @VanderbiltU 🎉 (1/3)