We are very excited to announce that early bird registration for European RosettaCon 2025 is now open!. More information here:

Science update: Designer Proteins Boost the Performance of Titanium Implants. Baker lab introduces NeoNectins, which help the body respond to surgical implants, healing gels, and other biomaterials. The study was led by postdoctoral scholar Xinru Wang, PhD, and visiting.

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We'd like to thank our generous sponsors for making Summer RosettaCon 2025 a successful event. Your support fueled innovation, collaboration, and community. Our sponsors for this year: Vilya , Lila Biologics, @Merck, @novoprotein , and Levitate Bio LLC. Explore these companies

Members of the IPD: Gaurav Bhardwaj, Frank DiMaio, and 2024 Nobel laureate David Baker have unveiled a deep-learning framework capable of the de novo design of macrocyclic peptides that bind proteins with nanomolar affinity and remarkable precision. This work is based on a report

Registration for Biomolecular Modeling and Design with Rosetta and ML Tools Workshop (November 17th – 19th, 2025) is now open. The goal of the workshop is to educate and train academic and industry users on the Rosetta software suite. Explore more:

We're excited to introduce our #RaMP 2025-2026 cohort. Watch this space for more updates.

RFdiffusion: Beta Documentation Now Available. We’re excited to announce that RFdiffusion now has official, Rosetta Commons-curated documentation! Read more:

RT @AjasjaLjubetic: We listened to your feedback. Proscuplt is:.*Easier to install - now uses use containers 🚀.*Easier to run in SLURM - sp….

We’re making a few intentional changes to our US-based Rosetta conferences next year to better support our growing community. We want to hear what you think. Learn more about the changes: Share your thoughts:

Rosetta Commons Biosecurity Fellowship now accepting proposals. This 12-month remote fellowship offers a unique chance to shape how protein design tools are developed and governed. Fellows lead their initiative, engage directly with Rosetta Labs and policy experts, and help.

RT @AjasjaLjubetic: 50% and higher experimental success rates would be a game changer and absolutely amazing. I just hope it's not a traini….

News from the Rosetta community: Prosculpt – an open-source library integrating RFDiffusion, ProteinMPNN, AlphaFold2 & Rosetta into one easy workflow. More via @AjasjaLjubetic:

RT @AjasjaLjubetic: Early bird registration for 𝐄𝐔 𝐑𝐨𝐬𝐞𝐭𝐭𝐚 𝐂𝐨𝐧 𝟐𝟎𝟐𝟓 is open! 🎉🎉🎉. Come join us for three days of protein design fun! (Octob….

Our Rosetta Commons Research Experience for Undergraduates (REU) students have completed the first leg of the program with the @jeffreyjgray lab at The @JohnsHopkins University and are now heading to their host labs for the summer. Stay tuned for more!

How to train your model. This immersive, hands-on, advanced-level event is designed for researchers who are ready to move beyond “out-of-the-box” machine learning models for protein design. Join us for this Summer RosettaCon 2025 workshop/hackathon, more here:.

Consider joining us for the 2025 Summer RosettaCon's 1-day Protein Design.AI-Driven Design of Biologics: Hands-on Guide to Using State-of-the-Art ML Protein Models brought to you by the Rosetta Commons. One-day novice-level course surveying popular tools and workflows for modern.