PataniLab
@PataniLab
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We use human stem cells to investigate Motor Neuron Disease / ALS @UCL & @TheCrick. Supported by the Medical Research Council & MND Association. #scicomm
London, England
Joined August 2015
Our latest @Brain1878: Elevated 4R tau drives neurodegeneration in VCP-related frontotemporal dementia. Link: Led by the very talented Dr Christy Hung (currently applying for faculty positions!) @Patanilab @The_MRC @UCLIoN @mndassoc @MNDoddie5 @TheCrick
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RT @MolNeuro: 'Human VCP mutant #ALS/#FTD #microglia display immune and #lysosomal phenotypes independently of GPNMB'. Benjamin E. Clarke &….
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Explore RNA regulation in neuronal development integrating microscopy, transcriptome and interactome-wide analyses .Postdoctoral Research Fellow opportunity in the laboratory of Professor Andres Ramos: .Link:
ucl.ac.uk
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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RT @Ben_ClarkeUK: Glad to see our review on the use of omics to study glia in ALS led by the superb Stan Majewski (not on X/Twitter) out in….
onlinelibrary.wiley.com
A graphical summary depicting the past and future of ALS glial research, which will require, alongside the application of molecular and cellular techniques, the utilization of more conventional and...
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Family Fun with the Patani lab @TheCrick !🧬🧑🧑🧒🧒 Come, check out our boardgame and discover your stem cell potential!🔬🧫 #DiscoveryDay
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RT @Ben_ClarkeUK: Free tomorrow? Why not come to the Crick for family fun at Discovery Day!. @PataniLab will be there 11-4 - come and play….
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RT @giulia_tyzack: Still looking for a talented and enthusiastic bioinformatician to work with us on a super exciting project on DNA damage….
ucl.ac.uk
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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RT @giulia_tyzack: We are hiring! The @PataniLab is looking for a bioinformatician to work on an exciting project on RNA metabolism and DNA….
ucl.ac.uk
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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RT @NatRevNeurol: APP antisense oligonucleotides reduce Aβ aggregation and rescue endolysosomal dysfunction in induced pluripotent stem cel….
academic.oup.com
APP gene dosage is strongly associated with Alzheimer’s disease pathogenesis. Hung et al. show that antisense oligonucleotides targeting APP can reduce APP
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RT @UCLBrainScience: "There is an urgent and unmet need for discovery of disease mechanisms in ALS in order to inform new treatment strateg….
ucl.ac.uk
Investigating strange forms of ribonucleic acid (RNA) associated with the formation of aggregates in the brains of ALS patients could lead to new avenues for treatments, a study involving UCL...
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RT @DiAntonioLAB1: Also massive thanks to @ListerInstitute that supports both myself and @RickiePatani and brought us together, playing a m….
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RT @DiAntonioLAB1: Thank you @h_dunning for covering our recent @NatureComms paper on RNA-mediated aggregation in ALS, work led by the amaz….
imperial.ac.uk
ALS INSIGHTS - Studying strange forms of RNA associated with the formation of aggregates in the brains of ALS patients could lead to new avenues for treatments.
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RT @ListerInstitute: We're thrilled that collaboration between our #ListerFellows @DiAntonioLAB1 and @PataniLab has contributed to this @Na….
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RT @ListerInstitute: We're so pleased to be able to bring great minds together @DiAntonioLAB1 @RickiePatani.
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RT @mndresearch: Unravelling what goes wrong in #MND is key to creating a world free of MND. @PataniLab are investigating whether DNA dama….
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RT @neuroblonde: It’s Dr Neuroblonde now! 👩⚕️Yesterday I successfully defended my PhD! 🎓 Immense gratitude to my incredible examiners @Sel….
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RT @Ben_ClarkeUK: Thrilled and incredibly grateful to have recently started a 3 year MND biomedical research project grant from the @mndass….
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RT @PataniLab: Our latest @Brain1878: Elevated 4R tau drives neurodegeneration in VCP-related frontotemporal dementia. Link: .
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RT @DiAntonioLAB1: Finally, and most importantly, this work is the result of a multi-collaborative effort and it could have not been possib….
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RT @DiAntonioLAB1: In this context we demonstrated how formation of intermolecular G4s can trigger aggregation of RNA expansion repeats tha….
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