Mol Syst Biol
@MolSystBiol
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#OpenAccess @EMBOpress journal publishing pioneering research in systems & synthetic biology, systems medicine Bluesky: @molsystbiol.bsky.social
Joined February 2009
2/2025 Issue ➡️ https://t.co/iI1ZsnpP62 biosensor screening for antivirals, cell type and subtype annotation, mutant PIK3CA reduces signaling specificity Cover (@TeamSciStories): PPI detection with improved split-intein system SIMPL and luciferase for quantification @stagljar
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Like @EMBO, find us now on the alternative platform where we will keep Molecular Systems Biology news and published articles updated!
EMBO shares news and updates on the alternative platform now. We'd love to stay connected! Find us there:
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I’m very much done with this app but here’s something for which I’m willing to come back & tweet… Our paper on the evolution of gene is just accepted at @MolSystBiol !🥳 Final version coming soon!
Our new preprint is out! Thread🧵 Genetic and selective constraints on the optimization of gene product diversity
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fast, reversible evolution of bacterial resistance to antibiotics is driven by epigenetic modifications while slow, irreversible evolution occurs via mutations in metabolic genes ➡️ https://t.co/z9ugay06MY
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chemoresistance to DNA damaging agent Gemcitabine may be overcome with synergistic action of ATR kinase inhibitors ➡️ https://t.co/E5BzS6x28M
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New Research Alert: Excited to share our work in @MolSystBiol. For why the combination of gemcitabine and ATR inhibition may be useful for the treatment of #PDAC patients: https://t.co/FtbbJpJ9Hg
@TU_Muenchen @MaxReichertMD
pubmed.ncbi.nlm.nih.gov
The DNA-damaging agent Gemcitabine (GEM) is a first-line treatment for pancreatic cancer, but chemoresistance is frequently observed. Several clinical trials investigate the efficacy of GEM in...
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New research from @LinkLabs reveals how metabolic mutations influence E. coli's antibiotic susceptibility ➡️ https://t.co/3D5iMEGHNv
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Deadlines are approaching for @KeystoneSymp Precision #GenomeEngineering : Translating the #HumanGenome to the Clinic, this March in Killarney, where MSB editor Poonam Bheda will be present! See: https://t.co/wnxXPMJyfs
#KSGenomeEng25
keystonesymposia.org
Join us at the Keystone Symposia on Precision Genome Engineering: Translating the Human Genome to the Clinic, March 2025, in Killarney, with field leaders!
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The @kusterlab's recent research provides a strong rationale for why the combination of gemcitabine and ATR inhibition may be useful for the treatment of #PDAC patients. 🖨️ @MolSystBiol
https://t.co/ntJtqfXGBO
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authors including @AvaKhamseh lab introduce Stator for improved cell type and subtype identification by multiply labeling individual cells with additional state information ➡️ https://t.co/wulh2wJ8iW
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multiplexed drug screening in using biosensors identifies antivirals against 40 viruses ➡️ https://t.co/90v3awqzuQ
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Work by @BVanhaesebroeck lab showing oncogenic PIK3CAH1047R reduces biochemical information transfer, corrupts growth factor signaling specificity and increases single-cell heterogeneity ➡️ https://t.co/p9YpSSHp41
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1/2025 Issue ➡️ https://t.co/Knp3U1xLUO L. pneumophila functional domains, analysis of human interactomes, increased sensitivity in cross-linking mass spectrometry Cover (@TeamSciStories): cis-regulatory elements in #KSHV and proximity to target over viral lifecycle @brittaspen
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Thrilled to share our latest work in @MolSystBiol, featuring SIMPL2, a game-changing tool for detecting protein-protein interactions with unmatched sensitivity and specificity. Will be featured on the Feb 2025 cover of @MolSystBiol! #DrugDiscovery #Innovation #SIMPL2
A team led by @UofT researchers has created a platform, called SIMPL2, that revolutionizes the study of protein-protein interactions. SIMPL2 can fast-track drug discovery for targeted treatment of diseases like #cancer. #UofT Learn more 👉 https://t.co/DIbI0eec7C
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🎉 Exciting news! Our paper on kidney cancer is now published! Check it out here:
embopress.org
imageimageIntegrative analysis of multi-omics and epidemiological data implicated ageing, epithelial-mesenchymal transition (EMT), and xenobiotic metabolism as biological mechanisms driving clear...
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Bacterial live therapeutics for human diseases "focus on preclinical and clinical trials of bacteria-based therapeutic products" https://t.co/dD1EEVJIiL
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The simplistic beauty of #XCMS-#METLIN precursor ion filtering combined with MS/MS matching to deconvolve data on 935K+ molecular standards to a couple of hits @MolSystBiol
https://t.co/GPuEtyAYMg XCMS-METLIN local for your PC now available at https://t.co/QDQw91JRYQ
Twenty years in the making, the #XCMS-#METLIN integrated platform is now available with the complete METLIN MS/MS 935K+ molecular standards database. Available as a local version on your own personal computer. For information visit https://t.co/QDQw91JRYQ
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High-throughput protein characterization by complementation using DNA barcoded fragment libraries https://t.co/nz3N5wAfOM
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