Are we too cortex exclusive? 🧠. We found that perceptual decisions depend on a cortical pathway through thalamus (transthalamic), even though corticocortical projections are intact. Transthalamic pathways thus play a major but underappreciated role in perception. 1/5

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RT @MillerLabMIT: Nice results. You can't understand cortex w/o the thalamus.Primate thalamic nuclei select abstract rules and shape pref….

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RT @SonjaBHofer: Great paper describing brain-wide coordination of neural activity during decision making.

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RT @DrGPluck: It's the cortical-subcortical circuits that matter, as always:.

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RT @cedricboeckx: Very nice work by @mo_brainer and colleagues,stressing once more the importance of the thalamus 👇.

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Link to paper:.

Big thanks to Claire McKinnon and Murray Sherman for seeing this through. This work was a collaboration between the @TheFlorey Institute and the University of Chicago. #cortex #transthalamic #thalamus #calciumimaging #neuroscience #optogenetics #perception #decisionmaking.

Transthalamic pathways are strong 'driver' projections, well-positioned to integrate top-down and bottom-up inputs for higher order cortex. These results build on excellent work which compared PT vs IT cortical cells @anne_churchland @simonMusall @mattlark @na0ya_takahashi.5/5.