Michael J. Kamal
@michaeljkamal
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PhD. Muscle Physiologist. Aging Scientist.š¬Satellite Cells š§¬ Senescence š§« Cellular Aging #myotwitter
Ontario, Canada
Joined March 2011
Itās #MicroscopyFriday so enjoy some beautiful NMJs taken by the Ljubicic lab here @McMasterU @MYOTWlTTER
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Chambers et al. w/@CoryDungan @Boehringer @prof_horvath @ClockFoundation @UKYCMB @UofA_ESRC @UARKHHPR @uacoehp @UArkResearch in @AgingCell Exploring epigenetic aging, senescence, and regeneration in skeletal muscle #myotwitter
onlinelibrary.wiley.com
Injury then recovery markedly rewires the DNA methylome in aged skeletal muscle.The addition of senolytics during muscle regeneration decelerates DNAmAGE more than regeneration alone as well as...
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Weāre excited to share that Gianni Parise has been named McMasterās next Vice-President, @McMasteResearch, starting July 1, 2025! š A seasoned leader & researcher in the Faculty of Science, heāll advance our research, innovation & global partnerships
news.mcmaster.ca
Following a competitive global search process, internationally recognized researcher and experienced university administrator Gianni Parise has been named McMaster's next Vice-President, Research....
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PhD defended and wrapped up! Couldnāt have asked for a better end to this (long) journey! Some of the people who made all this possible: @macgparise @mackinprof @KevinMurachPhD @mikhaiai @xhutid @steph_mattina and the twitter-less others - thank you
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Shoutout to the @McMasterU New Lyons Media centre for 3D printing these vertebrae for my anatomy lectures this week. They were a hit with the students!
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Preserving muscle with GLP-1 weight loss drugs: Big deal or nothing to worry about? https://t.co/FxzBZ0zUSS via @ConversationCA
theconversation.com
Early clinical trials suggest that people who lose weight with drugs like Ozempic lose lean mass as well as fat, which could have consequences for older adults at risk of muscle loss.
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New work from our group: Senescent myoblasts exhibit an altered exometabolome that is linked to senescence-associated secretory phenotype (SASP) signalling @AJPCellPhys #myotwitter
journals.physiology.org
Cellular senescence has been implicated in the aging-related dysfunction of satellite cells, the resident muscle stem cell population primarily responsible for the repair of muscle fibers. Despite...
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Our work is now online ā¦@NatureCommsā©! Led by ā¦@biancamarcella_ā© we show that GSK3 inhibition, alone or combined with exercise, can provide benefits to muscle and metabolic health in mdx mice!
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Travelled to Montreal to watch my friend & mentor Chris McGlory awarded the @csep_scpe Early Career Investigator award. Chrisā devotion to high quality science and supervision made CSEPās choice a no-brainer IMO! (Heās also recruiting if youāre looking for an excellent lab!)
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Now online! Great collab with @HorwathOscar @WiApro et al.
onlinelibrary.wiley.com
Background Sarcopenia is thought to be underlined by age-associated anabolic resistance and dysregulation of intracellular signalling pathways. However, it is unclear whether these phenomena are...
Excited to share that our latest is now accepted in Journal of Cachexia, Sarcopenia and Muscle @JCSM_cachexia. Stay tuned for the final version, until then have a look at the pre-print. @WiApro @MobergPhD @SebastianEdman @andyphilp_lab @nathanhodson5
https://t.co/Tw08aJpSbK
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Pairing with the article from McKenna et al. is this #Viewpoint from J. Max Michel (@AuburnKINES) and @michaeljkamal (@MacKinesiology). Michel and Kamal comment further on the comparative effects on Na+,K+-ATPase regulation! š https://t.co/jdqYf5TmeZ
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Hey Myotwitter! A call for papers in @AJPCellPhys edited by @thomashawke @CoryDungan and yours truly. We would love to see your work so send it our way! New AJP-CELL Call for Papers: Myogenic Stem Cells: From Single Cell Biology to Muscle Physiology
New AJP-CELL Call for Papers: Myogenic Stem Cells: From Single Cell Biology to Muscle Physiology https://t.co/m2OTSPqlkF
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Does a single night of restricted sleep alter indices of arterial structure and function? @joshuacherubini Jem L. Cheng, Calvin M. Armstrong, @michaeljkamal, @macgparise and @macdonmj (@MacKinesiology) investigate in this article! š https://t.co/RAkZSrPqW9
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Thank you to the team: @jemcheng, Jenna Stone, @michaeljkamal, @joshuacherubini, @macgparise, @macdonmj, & countless others who worked tirelessly on this project! #dreamteam
Excited to share our research which found that the menstrual cycle and oral contraceptive pill cycles (2 generations) had minimal impact on 20+ common cardiovascular outcomes & cellular regulation. Important considerations for female inclusion in biomed research. @ajpheartcirc
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Some very cool research here from @MACleod_JC and @mackinprof. We need more non-coding RNA studies in our field, seems like they might be a bigger factor than we realize!
Network-based modelling reveals cell-type enriched patterns of non-coding RNA regulation during human skeletal muscle remodelling
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šØ PhD opportunity šØ to be advertised soon, working with myself, @nathanhodson5, @Doc_Morse @Sale_ExNut @drhectorchinoy and others, investigating the mechanisms of and interventions for muscle loss in inclusion body myositis. If interested, please get in touch p.morgan@mmu.ac.uk
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Looking for an excellent postdoctoral fellowship in exercise physiology? Check out this great opportunity to work with Dr. Brian Irving. State-of-the-art laboratories and great scientific environment within School of Kinesiology at LSU. https://t.co/JdTeVSzjYi
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Had a great time at @BiochemExercise in Limerick. Saw some interesting posters, heard great talks, made new friends. Always a treat at #IBEC2024. Excited for the next round in Virginia!
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Following five wonderful years as a postdoctoral research fellow at @McMasterU under the expert guidance of @mackinprof , as of 1stĀ July 2024, Iām very excited to share that Iām starting a new position as an Assistant Professor in Nutrition and Healthy Aging in @ubcLFS at @UBC
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