@AmitaGuptaMD has spent more than a decade on a $70m trial to study a new TB drug, enrolling 6,000 participants in 13 countries. It might all have been for nothing. That's because an NIH policy has abruptly cut off billions to trials abroad. For @Nature.

This law authorizes the GAO head to sue if the President illegally impounds funds (as it did here). It has not yet done so, despite 4 findings of illegal impoundment this year, and Republicans are trying to hamstring GAO from doing so, NYT reports.

BREAKING: Watchdog government agency finds the NIH and the Trump administration have illegally withheld funds in violation of the Impoundment Control Act, and rips into HHS for failing to justify its slow-walking of funds.

NEW: A federal judge has demanded NSF explain in court how the UCLA grant suspensions are not in violation of her June order that restored grants to UC scientists

Full story @Nature here ⤵️. “The Senate’s recommendation of a $400m increase for NIH is an indication the agency still has support on Capitol Hill,” says @ZeitzerJennifer. “A 40% cut would have been devastating, so this is a good outcome in a tough year.”.

In a party line vote, the panel voted AGAINST including an amendment that would have reinstated frozen and terminated HHS (including NIH) grants. "Every President has the prerogative to implement new goals and priorities," says Sen Capito (R-WV).

The NIH budget would INCREASE by $400m — not slashed by 40%, as Trump proposed — in a proposal by Senate appropriators, says Sen Murray. "Some have asked if there will even be an NIH by [2029]. The commmittee's resounding message is yes—Congress has your back", she says.

RT @maxdkozlov: Hidden in the lungs of some breast cancer survivors are tumor cells that can remain dormant for decades — until they one da….

@NidhiSubs HHS spokesperson Andrew Nixon confirms: "The programmatic review is over. The funds are out.". No clarity on the topic of the "review" or the about-face that occurred yesterday.

@NidhiSubs Email from deputy director Matt Memoli to NIH leadership this morning:. "I am happy to report that due to the OD efforts, the funding restrictions have been fully lifted by OMB. We can resume all funding and obligations. Thank you for your patience with this brief pause.".

Hidden in the lungs of some breast cancer survivors are tumor cells that can remain dormant for decades — until they one day trigger a relapse. Now, a study shows these rogue cells can be roused from their slumber by viruses such as COVID-19 or the flu.

RT @Roy_Lab_Thinks: Amidst this chaos, current paylines have been revised due to "multi year funding" and many grants that were administrat….

Senior White House officials intervened to scrap the OMB effort to halt funding to the NIH, reports.@NidhiSubs, who broke the story for the WSJ.

The whiplash continues: WaPo reports that OMB halted, and then hours later unhalted, these NIH funds. I'll be monitoring the situation this week and will post more as I hear more. Know what's going on? Signal msg me at mkozlov.01. You can stay anonymous.

The White House heard all your concerns about 4% paylines. Their solution? 0% paylines.

administrative expenses, and Clinical Center expenses. Research grant, R&D contract, or training awards cannot be issued during this pause. We are working to make this limitation short-term and temporary, and will provide updates as available.".

I can confirm the news. Leadership received an email today saying . "NIH has received the full-year apportionment from OMB, but it contains a footnote that limits our obligations. At the moment, ASFR has interpreted this footnote to permit NIH obligations only for salaries. .

The NIH can’t award ANY grants to outside researchers under new WH restriction, reports @WSJ. This appears to be a prelude to rescissions and impoundment, especially after OMB director Vought's comments over the weekend.

The reprieve Congress gave to PEPFAR, the progam to combat HIV in developing nations, might be short lived. State Department officials have been mapping out a plan to shut it down in the coming years, reports @snolen.

Comparing these fields is unfair, particularly in light of efforts to abolish tenure across the country, @Shooshan5 says:. “Once a faculty member builds up momentum, the lab sustains it. In econ, every paper is a fresh start with a small number of coauthors”.

This analysis shows why so many researchers “feel completely burnt out by the time they get to tenure”, .@JessicaCalarco told me. A focus on metrics, such as number of publications or citation count, doesn’t emphasize quality, innovation or longer projects, she says.