“This #discovery paves the way to use these (long noncoding) #RNA molecules as a #therapeutictarget, which could mean a #paradigmshift in the treatment protocols of these diseases.” - @IRBBarcelona

A team led by researchers at @EPFL_en found that expression of the #longnoncodingRNA “CYTOR” is induced by exercise but declines during rodent and human skeletal muscle #aging.

New #research demonstrates the potential of #lncRNAs as #clinicalbiomarkers and potential #therapeutictargets, break new ground in #biomarker and #cancerbiology research and add to emerging #science about the role of #noncodingRNA in #cancer... @OICR_news

According to the new #research — conducted in mice implanted with human #prostatetumor samples — restoring this #longnoncodingRNA could be a new strategy to treat #prostatecancer that has developed resistance to #hormonaltherapies. - @WUSTLmed

https://t.co/O1c4nyCySP

Researchers from the @unav discuss the mechanisms of #lncRNA biogenesis, localization and functions in transcriptional, post-transcriptional and other modes of #generegulation, and their potential therapeutic applications.

This so-called “gene trap” could be exploited to disrupt other #longnoncodingRNAs and #genes. - @UNC_SOM

#LncExpDB is an expression database of human #lncRNAs that is devoted to providing comprehensive expression profiles of lncRNA #genes, exploring their expression features and capacities, identifying featured genes with potentially important functions.

“Only in recent years, with the #sequencing of the entire #transcriptome complete, have we realized how many #RNA species are actually present." - @ClemsonUniv

“#Cancer #lncRNAs that provoke #tumours represent an exciting new focus for the development of #cancertherapies” - @unibern

Researchers have uncovered a #longnoncodingRNA (#lncRNA) that may point the way toward new therapies for #atherosclerosis and shed light on why the likelihood of the disease increases with age.

As part of the @icgc_dcc Pan-Cancer Analysis of Whole #Genomes (#PCAWG) Consortium, @unibern researchers introduce the #CancerLncRNACensus (CLC), a compilation of 122 #GENCODE #lncRNAs with causal roles in #cancer phenotypes. - @GOLDLab_Bern

An international team led by researchers at the @embl report structural and functional studies of human maternally expressed gene 3 (#MEG3), a #tumorsuppressor #lncRNA that modulates the #p53 response.

Previously, it was believed that #lncRNAs served no major purpose in cells, but new research at @SyddanskUniv now shows that one of these lncRNAs termed ‘#lincIRS2’ is important for safeguarding our #metabolism

From a group of 245 #lncRNAs that were associated with melanomas researchers identified one, called #DIRC3, which acted as a #tumorsuppressor to block the spread of human #melanoma cells - @UniofBath @Ludwig_Cancer @sangerinstitute @unil

It has recently been shown that more than 90 percent of the #genome encodes a new and mysterious class of #RNAs, called #longnoncodingRNA molecules (#lncRNA). This is the first full 3-D structural study of lncRNA - @LosAlamosNatLab @uLethbridge @univienna

Seeking highly motivated applicants with a #PhD in #molecularbiology, #computationalbiology, #immunology or related discipline - @nyuschoolofmed

Researchers at @WUSTL found that key changes that occurred during #ricedomestication more than 9,000 years ago could be tied back to molecules called #longnoncodingRNAs (#lncRNAs), a class of #RNA molecules longer than 200 #nucleotides.

A team of researchers from @yonsei_u and @ilove_HYU said they have found a new #lncRNA #gene that controls the development of #esophagealsquamouscellcarcinoma (#ESCC), intractable #cancer in the esophagus.

By analysing hundreds of #tumour samples of children with #neuroblastoma, researchers at @KidsCancerInst found that high levels of the #longnoncodingRNA #lncNB1 are a #biomarker of poor prognosis.