Michael Lichten
@lichtenmj
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Molecular biologist, geneticist. Meiosis & homologous recombination. Opinions not US government policy.
Bethesda and Takoma Park MD
Joined January 2018
Been waiting for this since 2022 GRC!. Proximity labeling reveals new insights into the relationships between meiotic recombination proteins in S. cerevisiae
biorxiv.org
Several protein ensembles facilitate MutSγ crossover recombination and the associated process of synaptonemal complex (SC) assembly during meiosis, but the physical and functional relationships...
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Thrilled to hear it too!.
I was thrilled to learn I received the Yeast Genetics Meeting Lifetime Achievement Award!
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RT @lab_borde: Absence of chromosome axis proteins recruitment prevents meiotic recombination chromosome-wide in the budding yeast Lachance….
biorxiv.org
Meiotic recombination shows broad variations across species and along chromosomes, and is often suppressed at and around genomic regions determining sexual compatibility such as mating type loci in...
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Calendar marked!.
Mark your calendars, dear meiosis community! We have our location: #EMBOmeiosis 2025 will be in Engelberg, Switzerland, June 22-26. Organizers: Joao Matos, Mathilde Grelon, Takashi Akera @TakashiAkeraLab, John Weir @weir_science, Marinela Dukic and me (Image from Wikipedia).
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RT @chongyi_chen: Can we amplify RNA without reverse transcription to cDNA? Based on the finding that ssRNA template can be directly amplif….
genomebiology.biomedcentral.com
Existing single-cell RNA sequencing (scRNA-seq) methods rely on reverse transcription (RT) and second-strand synthesis (SSS) to convert single-stranded RNA into double-stranded DNA prior to amplifi...
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RT @lab_borde: A new preprint from Raphaël Guérois lab, @CejkaLab and @lab_borde uncovering the molecular mechanism that Sae2 uses to activ….
biorxiv.org
In S. cerevisiae , the Mre11-Rad50-Xrs2 (MRX)-Sae2 nuclease activity is required for the resection of DNA breaks with secondary structures or protein blocks, while in humans, the MRE11-RAD50-NBS1...
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The passing of a pioneer.
nytimes.com
Her findings led to breakthroughs in the treatment of cancer and in the understanding of the mechanics of evolution.
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RT @RonDePinho: I encourage every student to read Jim Haber’s (@Yeastdoc1 ) 101 years ago: Hermann Muller's remarkable insight | Genetic….
academic.oup.com
Abstract. More than 20 years before DNA was identified as the hereditary material, the Drosophila geneticist, Hermann Muller, envisioned the fundamental pr
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RT @Yeastdoc1: Last werkend my lab alumni gathered to celebrate 50 years at Brandeis and 80 years on earth.
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RT @mei_newt: We're now less than a year away from the 2024 Gordon Research Conference on Meiosis!.Jun 2-7, Colby-Sawyer College, New Londo….
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Hooray! Soon appearing in an SK1 strain near you!.
DNA polymerase δ: A single Pol31 polymorphism suppresses the strain ba.
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RT @MAYosis2023: The #MAYosis2023 program has been finalized and is available at We have an amazing line-up of spea….
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RT @Yeastdoc1: Thanks to a renewal of our NIH grant, Jim Haber’s lab has an opening for a postdoc to work on the fidelity of DNA repair in….
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RT @promiselcooper: Check out this work driven by the awesome Rishi Nageshan. Entangled telomeres? Expose them to the cytoplasm asap to r….
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RT @alhajijoker: Pls RT: Fully funded PhD studentship open for applications. Closes 13th April. #meiosis #recombination #yeast #genomics #m….
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RT @LabNeale: Are you interested in chromosome structure and DNA repair/recombination?.Do you want to explore biological mechanism and deve….
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RT @MAYosis2023: The MAYosis 2023 website is open!.5 sessions will feature 5 speakers; 1 keynote and 4 talks selected from abstracts. Only….
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