using a wide variety of techniques to analyze sequencing data, including non-negative matrix factorization. raw & processed data are available 🧠 check it out here!!

so excited to share that our preprint characterizing the dorsal anterior cingulate cortex in post-mortem human brain from @LieberInstitute is out! we integrated matched SRT and snRNA-seq data to investigate agranularity and von Economo neurons.

Join millions who have switched to Grok.

my work with @stephaniehicks and @BoyiGuo has been published in Biostatistics! tldr: the mean-variance bias exists in SRT data & impacts SVG detection. we propose #spoon, available on @Bioconductor, to address this! 🤩.

i had the great opportunity to present some of our work integrating dACC SRT and snRNA-seq data from neurotypical donors at #STATGEN2025 today! keep your eyes peeled for this project - coming out soon 🧠🧬

thank you so much to @BoyiGuo and @stephaniehicks for their amazing mentorship on this project. i’m so excited to have this project out now 🤓 3/3

we explored how the mean-variance relationship biases SVG detection in spatial transcriptomics datasets across various datasets and SVG detection tools. we then proposed #spoon - inspired by limma-voom - to correct for this bias! validated with simulated and real datasets 2/3.

i presented our recently preprinted work #spoon at the @CSHL Biological Data Science conference this past week! 1/3

RT @martinowk: Was just checking out some new analysis results from @kinnaryhshah - total 🔥, but every time I look at spatial expression ac….

new blog post about my first hackathon experience! thanks @StJude 💻

RT @jhubiostat: Thank you to all of the alumni, faculty, students, postdocs and friends who joined us for our @jhubiostat #JSM2024 receptio….

new blog post about simulating genomics data using the Poisson dist with a focus on understanding FDRs!

#STATGEN2024 was a fantastic meeting 🧬 the highlights were presenting my current research & meeting passionate folks in both academia and industry!.

RT @stephaniehicks: Very excited to be attending #STATGEN2024! 🧬. Presentations from me + @KasperDHansen's groups @jhubiostat. We've got lo….

RT @jhubiostat: Thank you to everyone you joined us for our #ENAR2024 Happy Hour at Ampersea in downtown Baltimore! It was great to see so….

super fun presenting at #ENAR2024 this morning and hearing about other great projects! as a bonus, i surprised @stephaniehicks with some live results showing that our method addresses the mean-variance bias in #spatial #transcriptomics data.

RT @martinowk: Had to share - I am so excited to see these - von Economo neurons in the human dorsal anterior cingulate - just such pretty….

super excited to announce that I passed my preliminary oral exam earlier this week! 🤓 i wrote up a blog post about the process and some tips for future students

I enjoyed engaging with other researchers at the 3rd Annual Single Cell Symposium! Very exciting to hear about new developments in the field & get some feedback on my current project #SCTC

RT @LindaOrzolek: Agenda is out for the 3rd Annual Single Cell Symposium! Join us in Baltimore, November 9-10! .#s….

new blog post about random seeds in #R! TLDR: don't use the same random seed to generate variables that shouldn't be correlated