RT @kyletucker93: My project is finally out! First ever cryo-EM structure of channelrhodopsin in a lipid nanodisc (I think?). So grateful f….

I once thought of ion channels as protein tunnels, built to exclude the membrane. Fitting that the one @stevebrohawn and I chose to study contains internal lipids central to channel function. Preprint on the LRRC8A:C volume-regulated anion channel:

RT @SteveBrohawn: New preprint! LRRC8A:C structures show how heteromeric volume-reg’d anion channels form + function with pore-embedded lip….

RT @SteveBrohawn: New preprint! @chrismhoel+Lin Zhang solved a cryo-EM structure of the 7TM TMEM87A + found (surprise!) it's related to the….

RT @SteveBrohawn: New preprint!! Cryo-EM structure SARS-CoV-2 M (50 kDa!) and MD sims give insight into M's essential role in virus assembl….

First paper from my little brother. I won't claim to have a strong understanding of QTLs, evolution, trans regulatory elements, etc. So my take home is that Biochemistry > Genetics once again :).

SARS-CoV-2 3a preprint update, 2.1Å! map with @AbhayKot @thermofisher, processed by me and @chrismhoel. We now have new PL uptake assays and RuR as an inhibitor from @sonalimali6 (Bautista Lab) and new 3a mutants patched by Ben Sorum. Led by @SteveBrohawn

RT @chrismhoel: Excited to share this new story from our lab, characterizing the structure and function of the 3a ion channel of SARS-CoV-2….

RT @KTckr: First graduate project published after such a long arduous journey.👴🏾👴🏾👴🏾👴🏾.#tomcomplex #mitochondria #proteinimport #cryoem #ne….

RT @biorxivpreprint: Cryo-EM structure of the mitochondrial protein-import channel TOM complex from Saccharomyces cerevisiae. https://t.co….