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Ken Hallenbeck Profile
Ken Hallenbeck

@kenkhallenbeck

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Ligand discovery in biotech & pharma @[email protected]

Lebanon. NH
Joined December 2010
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@kenkhallenbeck
Ken Hallenbeck
3 years
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@kenkhallenbeck
Ken Hallenbeck
1 year
Let me know if you have any trouble - I did my best full-stack dev impression but I am sure it isn't perfect :).
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@kenkhallenbeck
Ken Hallenbeck
1 year
If you want to submit to the database you *do* need an account: .
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@kenkhallenbeck
Ken Hallenbeck
1 year
If you don't want to make an account, you can directly access the Search function: .
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@kenkhallenbeck
Ken Hallenbeck
1 year
>1% of all papers published in 2023 used GenAI-provided text. It will only be higher in 2024+. Traditional Peer Review is not set up to catch them. I spent the weekend making a place to flag those papers - I hope it's a useful tool for the community.
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@kenkhallenbeck
Ken Hallenbeck
1 year
The first few levels of my upcoming game Research Rush went into open testing today! If you are on Android you can try it here: . iOS friends don't worry! The full release is coming in August with iOS support :).
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play.google.com
Casual Lab Sim - Upgrade your lab, build a team, and make discoveries!
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@kenkhallenbeck
Ken Hallenbeck
2 years
Hi! Popping back on here to promote my new non-fiction book, The Estonian Spy. This is a true story, written from eyewitness interviews of a survivor of the turmoil during the 1930s-50s. Part spy thriller, part memoir. If that's your thing, check it out:.
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amazon.com
In this remarkable true story, follow the transformation of Estonian Tom Saar from childhood refugee to Special Forces soldier. Born in 1934, Tom is forced to flee Estonia at age 5 and is recruited...
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@kenkhallenbeck
Ken Hallenbeck
3 years
Last year I left a fantastic job in #drugdiscovery at Genentech to start a new adventure. Why? . Too many next-gen drug modalities have purification problems that we can solve by applying drug discovery tools to #bioprocessing bottlenecks. Check it out:.
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@kenkhallenbeck
Ken Hallenbeck
3 years
So basically @joinmastodon servers are exactly like MMO servers with crossplay enabled. Oh no am I going to end up setting one up πŸ˜….
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@kenkhallenbeck
Ken Hallenbeck
3 years
Watching science Twitter try to figure out Mastadon πŸ‘€πŸ˜‚.
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@kenkhallenbeck
Ken Hallenbeck
3 years
I've always wanted to do mirror image directed evolution of peptide and small proteins to see what they can do. Brute force synthesizing a 100 kDa protein very cool but seems. less fun.
@AkosNyerges
Akos Nyerges
3 years
One major step toward mirror-image biology:. > Mirror-image T7 transcription of chirally inverted ribosomal and functional RNAs <. @ScienceMagazine.
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@kenkhallenbeck
Ken Hallenbeck
3 years
Whether in the form of peer review or not, that skill will remain extremely valuable precisely because there is so much bullshit grandstanding for the sake of securing funding and prestige.
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@kenkhallenbeck
Ken Hallenbeck
3 years
One thing that won't change, even if journals do?. The value of identifying a meaningful experiment.
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@kenkhallenbeck
Ken Hallenbeck
3 years
As a mentor of mine once said:. "Happy to do battle on any orthodoxy of order or format of submission".
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@kenkhallenbeck
Ken Hallenbeck
3 years
In case you missed it:
@eLife
eLife - the journal
3 years
Today, we’re introducing a new model that eliminates accept/reject decisions. By publishing every paper with eLife reviews as a Reviewed Preprint, we plan to restore autonomy to authors, ensuring that they will be judged by what, not where, they publish.
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@kenkhallenbeck
Ken Hallenbeck
3 years
Are we out here abolishing journals today??.
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@kenkhallenbeck
Ken Hallenbeck
3 years
Rejected from all three conferences I applied to speak at πŸ’”.
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@kenkhallenbeck
Ken Hallenbeck
3 years
As a scientist my heart says no. There is too much nuance in well-controlled experiments. But perhaps very useful for identifying data fraud or other plaigriarism. We never got to doing the experiment (funding ran out). Hopefully someonw does it! I'd be fascinated.
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@kenkhallenbeck
Ken Hallenbeck
3 years
We thought a lot about this @SciBaseReviews. The main idea was: Can peer review be done post-publication, formatted in a machine-readable format, then applied to future work?.
@RetractionWatch
Retraction Watch
3 years
"Can AI-estimated article quality be used to rank scholarly documents?".
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@kenkhallenbeck
Ken Hallenbeck
3 years
When Elsevier starts a Green Chemistry Journal:.
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