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Jonathan Basile Profile
Jonathan Basile

@jonothingEB

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Following
87K
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Author of https://t.co/ed6fmSC2Qg, postdoc, creator https://t.co/yg9BbWwTx3, he/him

Joined August 2009
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@jonothingEB
Jonathan Basile
4 months
This little pathogen I’ve created now has a life of its own. Virality Vitality, on the subterfuges of reproduction and contagion, has just been published!. Unfortunately, only in hardcover for the time being (; if you’d like to read it just get in touch.
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@jonothingEB
Jonathan Basile
24 hours
RT @bartlebytaco: massive.
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@jonothingEB
Jonathan Basile
4 days
Do I know anyone who's attending ISHPSSB? Or who just happens to be in Porto? Let's try to meet up.
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@jonothingEB
Jonathan Basile
6 days
Damn I really gotta finish Capital.
@Lannbutforbooks
Laann?!
10 days
I need your opinion would you read something like this ?
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@jonothingEB
Jonathan Basile
6 days
RT @spectraimsim: andrew cuomo actually put himself through college by running his father's failed 1977 mayoral campaign, which used the be….
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@jonothingEB
Jonathan Basile
6 days
In America, the only two jobs are prison guard or prisoner
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@amyklobuchar
Amy Klobuchar
7 days
NEWS: the Bureau of Prisons just decided to reverse course and keep their facility in Duluth open. I urged BOP leadership to take this step to protect these good paying jobs that are vital to the local economy.
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@jonothingEB
Jonathan Basile
6 days
My aim is to see the life sciences as deconstruction--their theoretical knowledge and practical mastery only takes place within contingent contexts that are destabilized by their own operations. Virality is one name for this expropriation of borders.
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@jonothingEB
Jonathan Basile
6 days
Our model of poliovirus was slightly revised, and he even patented a novel technique for attenuating viruses for vaccines. This is the only way the "new" emerges--as a failed replication.
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@jonothingEB
Jonathan Basile
6 days
Wimmer argued, against critics who said he was irresponsible, that he hadn't really done anything at all - merely actualized what everyone knew to be possible. Yet, against those who said it was a pointless publicity stunt, he pointed out that it provided new viral knowledge.
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@jonothingEB
Jonathan Basile
6 days
Far from an idle question, this has implications for the practice of public health--suspending a vaccination campaign once a disease is eradicated may only make its contagion more effective as a synthetic bioweapon.
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@jonothingEB
Jonathan Basile
6 days
Even fields of public health and epidemiology had to re-consider how they define viral eradication or extinction in light of this newly acknowledged possibility. If a virus can be "resurrected" from a computer database, is it ever really "extinct?".
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@jonothingEB
Jonathan Basile
6 days
Mail-order DNA synthesis companies began screening orders to try to prevent copycats from synthesizing their own bioweapons (even the companies themselves acknowledge this is not a fool-proof filter).
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@jonothingEB
Jonathan Basile
6 days
Even though the primary funder of this research was DARPA, many politicians called for new regulations of synthetic virology and biology to ward off national security risks, while scientists met to regulate themselves, trying to preempt external oversight.
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@jonothingEB
Jonathan Basile
6 days
When we re-think virology and virality on the basis of iterability, we can understand why an experiment that (according to the scientists performing it) demonstrated nothing new, nonetheless brought forward urgent political questions in every field it infected or touched on.
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@jonothingEB
Jonathan Basile
6 days
Because the apparent identity of the virus depends on its reproducibility or iterability, that identity is never fixed--every subsequent iteration can displace what seemed essential or intrinsic to it, and a site is always left open for parasitic or technological manipulation.
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@jonothingEB
Jonathan Basile
6 days
At the same time as we are confronted with this question, we come face-to-face with its unanswerability in principle. It is an arbitrary decision whether we say matter or information are literal or merely figurative viruses; yet, the pursuant practical concerns are no less urgent.
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@jonothingEB
Jonathan Basile
6 days
For a virologist such as Eckard Wimmer, synthesizing poliovirus brought forward the question: is a virus matter or information? Is it the "natural template" circulating as a strand of RNA, or is that sequence recorded in a computer database a true or literal virus?.
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@jonothingEB
Jonathan Basile
6 days
I take it in my book as an instance of deconstruction in and as the life sciences -- to many onlookers, this synthetic poliovirus appeared to demonstrate something already known and always true, yet, it shifted the ground under the feet of decisionmakers in numerous fields
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@jonothingEB
Jonathan Basile
6 days
It raised ponderous theoretical and ethical questions for scientists, while also provoking a panicked response from government officials concerned with regulating science and with national security, DNA-synthesis companies, epidemiologists, the media, and the public.
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@jonothingEB
Jonathan Basile
6 days
In 2002, a small group of virologists and biochemists synthesized infectious poliovirus from mail-order DNA fragments. I consider the implications of this experiment in the introduction of Virality Vitality /THREAD
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@jonothingEB
Jonathan Basile
7 days
Is this a joke? Why does it have perfect comedic timing.
@lizrhoffman
Liz Hoffman
7 days
Tough meeting for Mamdani with the Partnership for NY (CEOs) today I'm told. Stood his ground on "intifada" language and wouldn't commit to keeping NYPD Comm. Tisch, whom this crowd likes, in the job. (Also did not recognize her father, Jim Tisch, when he rose for a question).
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