Joe Winer
@joe__winer
Followers
899
Following
3K
Media
40
Statuses
469
neuroscientist studying sleep and memory in the aging brain | instructor at Stanford
San Francisco, CA
Joined January 2018
Very excited to share our new findings on REM sleep latency and AD biomarkersš§ - REM #sleep is more than a #DREAM! Special thanks to @Yunfeng_Zheng for making this fun and productive collaboration happen! @UCSFHospitals @UCSFPsychiatry @UCSFmac @alzassociation @SleepPIA
REM Sleep Delays May Indicate Early Alzheimerās A new study suggests that delayed rapid eye movement (REM) sleep may serve as an early indicator of Alzheimerās disease. Participants with delayed REM sleep showed higher levels of amyloid and tau, two proteins linked to
2
20
51
We are š¢hiringš¢ a research coordinator in the @MorminoLab at Stanford to work on exciting new sleep and aging projects!
careersearch.stanford.edu
The Mormino Lab within the Department of Neurology and Neurological Sciences is seeking a Clinical Research Coordinator Associate (CRCA) to work on...
0
21
37
Itās Tuesday in Philadelphia and weāre at Poster 490 talking about Sleep and Alzheimerās disease we have some interesting results so come out and hear about it!
2
5
66
Very excited about Alexās poster relating actigraphy-measured sleep with self reported next-day sleep quality. More to come soon from this project!!
@alex___washburn presenting his work on sleep in AD and LBD š“+ Alex and his mentor, @joe__winer at #AAIC24 šš§
0
1
14
Check out the #MorminoLab posters tomorrow at #AAIC24, with work from @pddocš©ø, @ClaireD_MDš§¬, and @joe__winerš“ @alzassociation @Stanford_Neuro
0
7
17
šš»Bravošš» to @joe__winer for a tremendous presentation to close out the āNeuroimaging Correlates of Risk and Protective Factorsā Scientific Session at #AIC #AAIC24 @NeuroimagingPIA @alzassociation
0
4
35
I am thrilled and very grateful that our project collecting and sharing actigraphy data across ADRCs has been selected by @NACCData! We are very excited to get started!
Please join us in congratulating this year's two awardees for the inaugural @naccdata and Gates Ventures AD/ADRD Digital Data Pilot Program! We are eager to see how these emerging digital solutions and digital data collection will transform AD/ADRD discovery and translation!
5
6
56
In @nytimes featuring our very own @joe__winer: "How Sleep Affects Your Risk of Dementia." For older adults, too much or too little sleep has been tied to cognitive issues. Learn more: https://t.co/7t9jZkgMCv
#Sleep #Dementia
nytimes.com
For older adults, too much or too little sleep has been tied to cognitive issues.
0
2
8
This is a really nice study showing (small) elevations in Alzheimer's and neurodegeneration biomarkers in the evening versus the morning. Toxicity of wakefulness! š¤Ŗ
šØNew paper out led by PhD Student @A_OrdunaDolado ā¼ļø "Effect of time of the day at sampling on CSF and plasma levels of Alzheimerās Disease biomarkersā now on @AlzheimersRes!
4
0
25
šWhat could be the role of plasma pTau181 in Lewy body disease? Our study shows that plasma pTau181 detects AD co-pathology, predicts baseline and longitudinal clinical outcomes, and identifies patients with increased risk of converting to MCI/dementia
onlinelibrary.wiley.com
Objective To determine whether plasma phosphorylated-Tau181 (pTau181) could be used as a diagnostic biomarker of concurrent Alzheimer's disease neuropathologic change (ADNC) or amyloidosis alone,...
1
17
35
Thrilled to be pitching (LIVE!) our pilot proposal to @NACCData @gatesfoundation on 5/31. We want to collect harmonized sleep and activity data across the NACC/ADRC network and make it freely available to researchers everywhere!
Congrats to the 6 teams competing for $250K - $1M in funding at the virtual pitch competition for the NACC/Gates Ventures AD/ADRD Digital Pilot Program! Join us in cheering on these teams May 31 at 1:00ā3:30pm ET. Register today, all are welcome: https://t.co/PrxNiFM8ZK
2
2
31
The evidence is better, I think, that extended *wake* leads to elevated production of amyloid and tau. One benefit of sleep may be to give the brain a break from the toxicity of wakefulness.
4
0
14
My experience talking about sleep in the aging and Alzheimer's field is that many take for granted sleep = waste clearance. But the evidence has been limited to a handful of studies, almost all in mice. This study is important evidence for reconsidering the role of sleep
Brain clearance is markedly reduced, not increased, during #sleep and #anesthesia in male mice https://t.co/zQv8xzwGNn
4
8
53
Interested in healthy aging? Memory mechanisms? Neuroimaging? Want to gain experience before applying to grad school? We are hiring a coordinator to work on the Stanford Aging and Memory Study (SAMS)! Apply at the link below! https://t.co/8zY6IezllS
careersearch.stanford.edu
The Mormino Laboratory within the Department of Neurology and Neurological Sciences is seeking a Clinical Research Coordinator Associates (CRCA) to...
0
20
32
Excellent new work from our own @DrMVanEgroo showing the importance of the #locuscoeruleus in sleep-wake regulation in Alzheimer's disease. With @grinberg_t, Eus van Someren & David Bennett @MaastrichtU @MGH_RI
onlinelibrary.wiley.com
Objective While studies suggested that locus coeruleus (LC) neurodegeneration contributes to sleepāwake dysregulation in Alzheimer's disease (AD), the association between LC integrity and circadian...
3
16
42
Our paper on impaired sleep-wake rhythms predicting future Alzheimer's, Parkinson's, and cognitive decline in the UK Biobank actigraphy cohort (N=82,829!) is out now in @AlzheimersRes ! āļøš“šāāļøš§ https://t.co/mqiwLgQEpD
alzres.biomedcentral.com
Background Sleep-wake regulating circuits are affected during prodromal stages in the pathological progression of both Alzheimerās disease (AD) and Parkinsonās disease (PD), and this disturbance can...
0
21
98
If you work in sleep/AD research, have your say! Complete our Delphi survey for consensus recommendations on sleep/circadian measures. Proud of this global collaborative work supported by @SleepPIA of @alzassociation @claire_c_andre @cogsleep
https://t.co/cfPfyzBvMC
0
6
10
Penguins snatch seconds-long microsleeps | Science
science.org
Chinstrap penguins fall asleep thousands of times per day in the wild
1
11
44
Check out Dino's (@leonardinosaur) excellent and important new piece on anti-amyloid therapies, written with Mike Greicius
With #CTAD23 happening, it is an exciting week for the AD field. To contribute to the discussion, we (I, @joe__winer, and Mike Greicius) wanted to highlight three observations regarding recent anti-amyloid clinical trials: https://t.co/2yNv4UZ9PJ
0
2
12