Joe Winer
@joe__winer
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neuroscientist studying sleep and memory in the aging brain | instructor at Stanford
San Francisco, CA
Joined January 2018
RT @YueLengsleep: Very excited to share our new findings on REM sleep latency and AD biomarkersš§ - REM #sleep is more than a #DREAM! Speciā¦.
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We are š¢hiringš¢ a research coordinator in the @MorminoLab at Stanford to work on exciting new sleep and aging projects!
careersearch.stanford.edu
The Mormino Lab within the Department of Neurology and Neurological Sciences is seeking a Clinical Research Coordinator Associate (CRCA) to work on...
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Itās Tuesday in Philadelphia and weāre at Poster 490 talking about Sleep and Alzheimerās disease we have some interesting results so come out and hear about it!
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Very excited about Alexās poster relating actigraphy-measured sleep with self reported next-day sleep quality. More to come soon from this project!!.
@alex___washburn presenting his work on sleep in AD and LBD š“+ Alex and his mentor, @joe__winer at #AAIC24 šš§
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RT @MorminoLab: Check out the #MorminoLab posters tomorrow at #AAIC24, with work from @pddocš©ø, @ClaireD_MDš§¬, and @joe__winerš“ @alzassociatiā¦.
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RT @MorminoLab: šš»Bravošš» to @joe__winer for a tremendous presentation to close out the āNeuroimaging Correlates of Risk and Protective Facā¦.
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I am thrilled and very grateful that our project collecting and sharing actigraphy data across ADRCs has been selected by @NACCData! We are very excited to get started!.
Please join us in congratulating this year's two awardees for the inaugural @naccdata and Gates Ventures AD/ADRD Digital Data Pilot Program! We are eager to see how these emerging digital solutions and digital data collection will transform AD/ADRD discovery and translation!
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RT @StanfordADRC: In @nytimes featuring our very own @joe__winer: "How Sleep Affects Your Risk of Dementia." For older adults, too much orā¦.
nytimes.com
For older adults, too much or too little sleep has been tied to cognitive issues.
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This is a really nice study showing (small) elevations in Alzheimer's and neurodegeneration biomarkers in the evening versus the morning. Toxicity of wakefulness! š¤Ŗ.
šØNew paper out led by PhD Student @A_OrdunaDolado ā¼ļø."Effect of time of the day at sampling on CSF and plasma levels of Alzheimerās Disease biomarkersā now on @AlzheimersRes!.
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RT @carlaabdelnour: šWhat could be the role of plasma pTau181 in Lewy body disease? .Our study shows that plasma pTau181 detects AD co-pathā¦.
onlinelibrary.wiley.com
Objective To determine whether plasma phosphorylated-Tau181 (pTau181) could be used as a diagnostic biomarker of concurrent Alzheimer's disease neuropathologic change (ADNC) or amyloidosis alone,...
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Thrilled to be pitching (LIVE!) our pilot proposal to @NACCData @gatesfoundation on 5/31. We want to collect harmonized sleep and activity data across the NACC/ADRC network and make it freely available to researchers everywhere!.
Congrats to the 6 teams competing for $250K - $1M in funding at the virtual pitch competition for the NACC/Gates Ventures AD/ADRD Digital Pilot Program! Join us in cheering on these teams May 31 at 1:00ā3:30pm ET. Register today, all are welcome:
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The evidence is better, I think, that extended *wake* leads to elevated production of amyloid and tau. One benefit of sleep may be to give the brain a break from the toxicity of wakefulness.
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My experience talking about sleep in the aging and Alzheimer's field is that many take for granted sleep = waste clearance. But the evidence has been limited to a handful of studies, almost all in mice. This study is important evidence for reconsidering the role of sleep.
Brain clearance is markedly reduced, not increased, during #sleep and #anesthesia in male mice.
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RT @MorminoLab: Interested in healthy aging? Memory mechanisms? Neuroimaging? Want to gain experience before applying to grad school? We arā¦.
careersearch.stanford.edu
The Mormino Laboratory within the Department of Neurology and Neurological Sciences is seeking a Clinical Research Coordinator Associates (CRCA) to...
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RT @HeidiJacobsLab: Excellent new work from our own @DrMVanEgroo showing the importance of the #locuscoeruleus in sleep-wake regulation inā¦.
onlinelibrary.wiley.com
Objective While studies suggested that locus coeruleus (LC) neurodegeneration contributes to sleepāwake dysregulation in Alzheimer's disease (AD), the association between LC integrity and circadian...
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Our paper on impaired sleep-wake rhythms predicting future Alzheimer's, Parkinson's, and cognitive decline in the UK Biobank actigraphy cohort (N=82,829!) is out now in @AlzheimersRes ! āļøš“šāāļøš§
alzres.biomedcentral.com
Background Sleep-wake regulating circuits are affected during prodromal stages in the pathological progression of both Alzheimerās disease (AD) and Parkinsonās disease (PD), and this disturbance can...
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RT @Prof_Naismith: If you work in sleep/AD research, have your say! Complete our Delphi survey for consensus recommendations on sleep/circaā¦.
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RT @VVyazovskiy: Penguins snatch seconds-long microsleeps | Science
science.org
Chinstrap penguins fall asleep thousands of times per day in the wild
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Check out Dino's (@leonardinosaur) excellent and important new piece on anti-amyloid therapies, written with Mike Greicius.
With #CTAD23 happening, it is an exciting week for the AD field. To contribute to the discussion, we (I, @joe__winer, and Mike Greicius) wanted to highlight three observations regarding recent anti-amyloid clinical trials:.
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