Jinay
@jinaycodes
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@chaidiscovery scholar @neo, prev HFT, @MaticRobots, @schoolhouse_edu
Joined December 2017
I can't wait for the day these breakthroughs transform the lives of real people. In hindsight, $130M will have been a small price to pay. We're hiring!
We raised $130M in Series B funding at a $1.3B valuation to build the computer aided design suite for molecules. The round was led by @GeneralCatalyst & @OakHCFT along with existing investors @ThriveCapital, @OpenAI, @_DimensionCap, @Neo, @lachygroom, @MenloVentures, @svangel,
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after months of antibody design papers that only work on single chains, we are seeing much-needed progress on full IgG congrats to the chai team!
Today, we’re releasing new data showing that Chai-2 can design antibodies against challenging targets with atomic precision. >86% of our designs possess industry-standard drug-quality properties without any optimization. Thread👇
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Chai-2 is a great model, sir. Oh yeah, and I joined @chaidiscovery a few months ago. Beyond blown away by what this team has accomplished already.
Today, we’re releasing new data showing that Chai-2 can design antibodies against challenging targets with atomic precision. >86% of our designs possess industry-standard drug-quality properties without any optimization. Thread👇
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Most AI systems today follow the same predictable pattern: they're built for specific tasks and optimized for objectives rather than exploration. Meanwhile, humans are an open-ended species—driven by curiosity and constantly questioning the unknown. From inventing new musical
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Cool to see a company putting this into a real product. This was my vision behind building Memory Lane in 2023! https://t.co/urAC2QuDKq
https://t.co/nTkTMpqn0q
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if you enjoyed this thread, you might also enjoy my deep dive thread on formalizing scientific discovery https://t.co/1uZkbjPszH
can we develop a formalized theory of scientific discovery? today's deep dive thread is on the philosophy of science:
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@kenneth0stanley @jeffclune @_rockt @jennyzhangzt Some things I'll be watching/reading next: "Novel Opportunities in Open-Endedness" -- this shows how open-endedness is different from existing hillclimbing vai toy example https://t.co/1AtwTZWp4s "Open-Endedness, World Models, and the Automation of Innovation"
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For further reading, I recommend following these people and their work: @kenneth0stanley @jeffclune @_rockt @jennyzhangzt
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The rest of the paper talks about how open-ended ASI could remain safe and aligned. Open-ended systems need to maintain a two-way street with humans so that they remain aligned to human goals while providing us a new understanding of the world.
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The other 3 proposed paths are similar to RL in that they are ways for an agentic AI to adapt to its environment. - self improvement: model evaluates its own performance and tweaks itself to do better next time. - task generation: model sets goals for tasks to achieve in its env
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AlphaGo and others demonstrate how reinforcement learning can achieve superhuman open-ended systems. Exploration techniques induce novelty and the use of critics shows that these outputs can be learnable as well. LLMs are showing lots of promise right now with RL too, even
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The authors believe we need open-endedness for ASI, and propose a couple paths for reaching open-endedness by altering how we train foundation models. The obvious first idea is using RL.
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today, we have systems that are either: - general and not open-ended - open-ended but not general AlphaGo is open-ended but only in the domain of Go. It generates novel strategies, which a human is able to learn from, making it open-ended. Modern LLMs are general but not
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practical systems have limitations to this abstract definition. humans are the most common observer for these open-ended systems, but we have limited memories. so the learnability of anything we observe plateaus when we reach those limits. for example, if you started reading
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this definition incorporates both novelty and learnability--both of which require an observer that judges these qualities. Novelty is a system's ability to keep creating things that the observer didn't predict. Learnability is when something becomes more predictable the more
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first, what is open-endedness? informally, it's giving AI creativity: the ability to continuously generate novel outputs formally, the paper defines it as:
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how do we get truly novel outputs from AI? major labs including DeepMind and OpenAI have had teams dedicated to open-endedness. makes sense given the impact it could have on enabling discovery and self-improvement. doing today's deep dive thread on this field:
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