Reid Hoffman
@reidhoffman
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Co-Founder, LinkedIn. Currently using AI to cure cancer faster @manas_co.
Joined October 2006
Today, I launched Manas AI –– a full stack AI company setting out to shift drug discovery from a decade-long process to one that takes a few years; bringing life-saving treatments to patients faster than ever.
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Reddit user shares how ChatGPT fixed a medical issue they had for 5 years. Replies are flooded with users who had the same condition, and finally found answers too. Superagency!
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MAGA fundraiser David Sacks’ recent open letter explaining his support for Trump over Biden got it wrong on just about every count, awkwardly regurgitating pro-Trump groupthink. David makes four specious main points:. (1) Trump’s legal troubles result from Joe Biden’s.
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Just one more of Elon's false claims about me: I never funded anyone for Tesla protests. I don’t condone violence. But it's clear Americans are angry at him – it’s easier to explain away their anger, than to accept that actions have consequences.
An investigation has found 5 ActBlue-funded groups responsible for Tesla “protests”: Troublemakers, Disruption Project, Rise & Resist, Indivisible Project and Democratic Socialists of America. ActBlue funders include George Soros, Reid Hoffman, Herbert Sandler, Patricia Bauman,.
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I don't know about islands but here's your least favorite mountain
Describe your favorite island vacation.
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Business leaders need Harris' stability, not Trump's chaos. My op-ed in Bloomberg: .
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Good to see so many CEOs—Mark Cuban, Reed Hastings, Ken Frazier, Aaron Levie, and Ken Chenault, to name a few—join me to break down why VP Harris is better than former President Trump for business, for jobs, and for the American economy.
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Not surprised to see Trump's attacks on @elonmusk. Elon's a classic 🇺🇸 immigrant story - an entrepreneur with a real record of success. Started EV revolution w/Tesla, resurrected US rocket industry w/SpaceX, fighting climate change while promoting American innovation.
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For the last three presidential elections, I've been making the case that Donald Trump threatens the rule of law, creates constant chaos, and always puts his own interests above America's. All of these things make it harder for American businesses to operate efficiently and plan.
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After more than 1,000 board meetings at Microsoft, Airbnb, LinkedIn, PayPal, and more. I've learned that effective boards don't happen by accident. Here are 8 rituals of the world's best boards: 👇.
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Joe Biden is a leader who acts with the best interests of America in mind. Not seeking re-election is one of the most selfless acts we’ve seen from a politician in modern American history. This is what’s right for our country—and our democratic future.
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@elonmusk @TeslaBoomerMama The probability many, many people don't like you? 100%. Probability that Tesla polls need to be rigged by bots to cover up the fact that people don't like you? 100%. Probability you'd rather make shit up about me than fix your problems? 100%.
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On the All-In Podcast, I was asked whether I agree with a large unrealized gains tax. My red line isn't taxes. My red line is January 6. Coups against our country are inexcusable.
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I believe starting a company is like jumping off a cliff and assembling a plane on the way down -- your willingness to jump is your most valuable asset as an entrepreneur.
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Immigration is pure entrepreneurship. You leave behind everything familiar to start somewhere new. You must acquire skills. You will have to improvise on occasion. It’s a bold proposition.
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As important as it is to never forget the terror attack that took place a year ago today on our Capitol, it's equally important to remember that Donald Trump's War on Democracy neither started nor ended on 01/06/20.
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I wrote a new book with @OpenAI’s latest, most powerful large language model. It’s called Impromptu: Amplifying our Humanity through AI. This, as far as I know, is the first book written with GPT-4. Here’s how it all began… .
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President Biden is fundamentally more pro-business than President Trump.
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Why did I deepfake myself? To see if conversing with an AI-generated version of myself can lead to self-reflection, new insights into my thought patterns, and deep truths.
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My message for American voters and Russian bots: don't vote for the guy too busy selling you a scamcoin. Vote for Vice President Harris, who knows how to put business—and the American people—first.
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My view on which candidate in the US election is best for American business: Joe Biden.
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Best news: this can be a reality for every student, anywhere.
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Inspired by @Lin_Manuel, I produced a battle rap music video about centralized and decentralized currencies, pitting Alexander Hamilton against Satoshi Nakamoto. Watch the full video: 👉 Trailer below.
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Gov. Walz is a lifelong public servant who represents the best of our country. A dedicated teacher, former guardsman, an advocate for women’s health, and a family man, he cares deeply about America's future. Together, Harris and Walz will fight for everyone—no exceptions.
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First and everything: There is no place for political violence in our society. Assassination is not only categorically wrong, but is also the assassination of democracy. It is abhorrent that anyone has tried to assassinate President Trump. Everyone, on all sides of this.
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"We are entering a new era of coding." . Nobel Prize Winner and @GoogleDeepMind CEO Demis Hassabis on coding with natural language.
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@sama That you should engage with the smartest, most compelling people who disagree with you to learn and evolve your thinking. (Obviously wish more people did this.).
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Congratulations to my longtime friend @MarkJCarney on his election victory. Leaders with a clear grasp of the global economy are precisely what this moment calls for.
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VCs must hold the same moral position to entrepreneurs as manager/employee or professor/student #DecencyPledge.
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Inspired by the potential of DALL•E and NFTs — and the possibilities that they unleash together — my team and I have created a number of small image collections that we'll be tokenizing as NFTs. The first collection debuts on Magic Eden today. Here's why I'm experimenting:.
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" I think maybe in the next 10, 15 years we can actually have a real crack at solving all disease.". Nobel Prize Winner and DeepMind CEO Demis Hassabis on how AI can revolutionize drug discovery doing "science at digital speed."
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There is no such thing as a balanced life in startups––everyone from the CEO down is responsible for setting a culture where people want to work extremely hard and win.
I'll never bet on a founder who doesn't work on the weekends.
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Kamala Harris is the right person at the right time. Donald Trump and JD Vance are promising an agenda that will wreak havoc on the American people. Harris’s background and leadership growing the economy, fighting for bodily autonomy, and protecting our democracy uniquely.
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The Democrats had the best incumbent-party midterm in decades. American voters said “No” to GOP extremism and Trump-backed insurrectionists.
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If I had a nickel for every time someone confused me with Reed Hastings, I would be a billionaire.
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Trump, OTOH, is a spoiled rich kid who bankrupts everything he touches. Including the US economy. His career highlight was pretending to be a successful entrepreneur on a TV show, instead of being one in real life like Elon.
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“Starbucks is not profit-driven. Starbucks is values-driven, and as a result of those values, we have become very profitable.” —Howard Schultz, Starbucks.
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We now have a President-elect of the United States: Donald Trump. It is clear that he has again won the presidency in a country where we enjoy relatively unfettered rights to vote, speak out, and steer our futures. In January, we will enjoy a peaceful transfer of power. Peaceful.
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Prompting is one of the most important skills we need to develop––thinking about some ways to help people learn it quickly.
Most people are still prompting wrong. I've found this framework, which was even shared by OpenAI President Greg Brockman. Here’s how it works:
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I believe every business is an experiment. For the experiment to succeed, you need to test your hypothesis, measure the results, and follow where they lead.
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With AI, "we did 1,000,000,000 years of PHD time in one year." . Nobel Prize Winner and @GoogleDeepMind CEO @demishassabis on AlphaFold, the groundbreaking AI system developed to solve one of biology’s most complex problems: protein folding.
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Important. This administration continues to erode trust in the American markets, first with crypto grifts, and now with tariff policies drafted by a team that can't even do basic mathematics. This is a long game to hurt everyday Americans and consolidate power at the top.
Those trying to understand the tariffs as economic policy are dangerously naive. No, the tariffs are a tool to collapse our democracy. A means to compel loyalty from every business that will need to petition Trump for relief. 1/ A 🧵 to explain his plan and how we fight back.
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@paulg More young people want to explore entrepreneurship, and we should build more platforms to support that. We should also ditch incentive structures that make high schoolers feel like they need to be unicorn founders to get into college. That’s not healthy.
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The Democrats are the party of policy, progress, and action. When presented with the choice between Kamala Harris and Donald Trump, I believe in the American people to make the right decision for our country. The Biden-Harris administration has put this country on the right.
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Joe Biden has already received more votes than any candidate in history - 69 million-plus and over 50% of the total cast. The American people are speaking. We must respect their will and count all votes.
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Changing the way the world works. Amplifying the path forward! @jeffweiner and Satya Nadella
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@Jason @DavidSacks I'm game. Unfortunately, I can't make Summit. Let's figure out a way. Maybe on the pod?.
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Personally, I support people working to build a better future for America and the world. Trump is such a stuck-in-the-past sore loser that he'd rather spread lies, incite insurrection and damage American democracy than admit he lost a fair election.
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Blitzscaling your company isn’t easy; if it were, everyone would do it. Like most things of value in this world, blitzscaling is contrarian and unique.
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Most entrepreneurs assume they know what customers want - those assumptions are based on instinct and experience. But intuition is no match for data. Think like a scientist and design experiments; test a hypothesis; then try again. @mastersofscale #MindsetChallenge.
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So many special moments in yesterday's #MastersofScaleSummit, but a surprise conversation with @Arobichaux and Prince Harry about @Betterup's mission to democratize coaching was an incredible way to wrap up the day.
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Speed is one of your key advantages as a startup. But strategic patience is another — knowing when to wait, and when it's time to strike. Timing is everything. The key? Stay ready to move with explosive speed. @mastersofscale #MindsetChallenge.
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Here's a story I’ve rarely told. How I knew it was time to create LinkedIn:.
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Need to shift the mindset from "AI will replace me." to "A human who is better at using AI will replace me.".
Nobody wants to hear AI is better than them in a profession.
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You may have heard me say: If you're not embarrassed by the first version of your product, you've launched too late.
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I would like to hear the president denounce this and things like it.
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This election isn't about minor policy disagreements. It's about truth vs. fiction, the rule of law vs. chaos, and democracy vs. fascism. That's why I've backed Kamala Harris—and you should, too.
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Spending the day playing with LLaMA 4. One of many interesting things. the massive context window is a game-changer. I don't think it's the end of RAG, but for a surprising number of workflows, the long context alone is enough. Thoughts?.
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Have been a supporter of this project for a while––Matt & team at $YNE are exploring a great use of AI agent+token to provide a tangible public good (auditing research). Excited to see the experiment grow.
We are less than 60 days into the creation of @yesnoerror, the AI agent that is auditing all scientific research, powered by the $YNE token on Solana. What started as a viral experiment launched on @pumpdotfun, has grown into something much more serious, and we're fully leaning
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Reflection on my time investing – one of my early mistakes was to focus the majority of my time helping "problem companies" versus spending time hyperscaling the companies that were doing really well.
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Trump does have the unique achievement of personally profiting from running money-losing casinos. (He's great as a grifter.).
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When you make a fast decision as a leader, the gift you’re giving your team is TIME. Every minute you deliberate is a minute your team can’t use to execute. Today's lesson = Decide, decide, decide! #MindsetChallenge.
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100% not — at least so far. I’d be interested to learn if and which organizations might actually be doing something.
So are you funding?.
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5 takeaways for serial entrepreneurs from my conversation with @ev:. 1. Bet on the way the world is moving. 2. Start from where you are. 3. Don’t worry about a wipeout. 4. Persevere. And position yourself for luck. 5. Don’t derail your own destiny.
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@hahabusinessinc I'm not sure they'll hate it. If implemented correctly, AI could help doctors diagnose individual patients faster, do less paperwork, and see more patients in a day.
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In my first startup, I was told “no” by almost every VC I pitched.
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I rarely agree with my friend @peterthiel but always respect him. Thrilled he's on tomorrow's @mastersofscale season premiere.
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I’ve turned these 8 rituals of great boards into a set of tools you can copy and use.
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Airbnb's @bchesky went door to door to his customers. What's the craziest thing you've done in the name of entrepreneurship? #MastersofScale.
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A 26-year-old Marine Corps Vet has a plan to liberate Trump’s tax returns (on @Crowdpac):
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My favorite Heraclitus quote: "A man cannot step into the same river twice, because it is not the same river, and he is not the same man.". Made a quick trip to Oxford today. The time I spent immersed in philosophy on campus impacts my life daily. Photos from 1993 & 2025
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I’ve said this before, but: If you're not embarrassed by your first product release, you've released it too late. Move at the speed of opportunity. @mastersofscale #MindsetChallenge.
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This is a massive milestone for @boomaero, for America, and for humanity.
Boom! We cracked it! Today we are introducing Boomless Cruise—supersonic flights up to 50% faster with no audible sonic boom. We quietly (har har) demo'd this on XB-1's first supersonic flight—three times actually. 🧵👇
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We all—especially those in business—have a responsibility to uphold a shared rule of law for a chance at prosperity for generations to come. Absent this, the US would never have developed as the biggest, most productive business ecosystem ever known.
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I came across this video of Justin Bieber using a full orchestra to turn the rhythms in his mind into music. Soon, anyone will be able to hum a tune, describe the vibe you’re aiming for, and have an AI-powered producer turn your ideas into reality.
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ASKING FOR A FRIEND: Going forward, will all federal policy announcements just be grifty insider pump-and-dumps?.
Someone went 50X long at $85,880.80 with $200M on the line. This may be the boldest single trade I have ever witnessed in any market, with any asset, ever. Two. Hundred. Million. Dollars. Placed right before Trump made his tweet about the crypto reserve. Surely, just luck.
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What would you say to your younger self at pivotal moments in your career? I used AI to create a younger Reid AI—from 2004!—so we could talk about pitching LinkedIn's Series B deck to investors.
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This week on Possible, we sit down with Nobel Prize Winner and @GoogleDeepMind CEO @demishassabis to discuss his predictions on the next “move 37”, protein folding, and why AI will be the “most transformative technology ever.”
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In 2004 @LinkedIn pitched @GreylockVC for Series B funding using this deck. I break down what worked and what didn't: http://t.co/GaYzseLCzq.
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Results aside, grateful for this year’s concession speeches. Per 🇺🇸 tradition, losing candidates of both parties publicly conceded to winning candidates. So basic. And yet another rebuke to Trumpism.
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4 years ago I invested $30m in because it’s an essential service for citizen voice. Today I’m proud to donate all my equity to secure its long-term stewardship in the public interest.
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A great question @StevenBartlett asked me while recording Diary of a CEO last week was: “How do you know you’ve found a good idea?” The answer is a bit counterintuitive: you want to look for the ideas smart people think are bad. Being contrarian isn’t about finding easy research
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I try to do one deep research prompt a day. Instant expert-level information on something unique to my interests! It's a great way to feel the intelligence amplification that awaits us in the age of AI.
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Might be a hot take: Ads keep the internet accessible. For example, people assign $17.5K of value to search a year, and $3.6K for maps. Instead of killing ads, let's use AI to make ads more relevant to users and advertisers. That itself is a form of service improvement.
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Congratulations to new #VPPick @KamalaHarris! And to @JoeBiden, for adding such a strong, experienced, and inspiring leader to the team. The two of them together will help restore the values and ideals that America needs to prosper in the 21st century.
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I am matching $2 for $1 donations to @2ndHarvest, a food bank serving an average of 500,000 people in Silicon Valley every month, twice the amount pre-pandemic. Join me in ending hunger. #GiveWhatMatters
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