Jason Kwon
@jasonkwon
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“OpenAI is now able to release open weight models that meet requisite capability criteria.” let’s gooooo
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starting a new chapter
We completed our recapitalization. The non-profit, the OpenAI Foundation, is now one of the best resourced philanthropies ever, with equity valued at ~$130B. It continues to control the OpenAI for-profit, which is now a public benefit corporation. https://t.co/TevJDA3QwB
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Pretty pumped to back Valthos @foundersfund, a biodefense company protecting us from the threats too microscopic for Anduril to handle. 🔬☣️
Valthos builds next-generation biodefense. Of all AI applications, biotechnology has the highest upside and most catastrophic downside. Heroes at the frontlines of biodefense are working every day to protect the world against the worst case. But the pace of biotech is against
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Big supporter. I find model weight security somewhat overrated, and “wow, some large fraction of the cognitive labor done by the national security apparatus will be done in data centers soon, we really need to make sure those data centers are secure in every way” underrated.
Direct quote from PDF: > OpenAI proposes a “Classified Stargate” initiative to help meet this need—mobilizing private capital alongside government partners to establish accredited, classified data centers purpose-built for government AI.
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🧵Today we’re sharing more details about improvements of the default GPT-5 model in responding to sensitive conversations around potential mental health emergencies and emotional reliance. These changes reflect the careful work of many teams within OpenAI and close consultation
Earlier this month, we updated GPT-5 with the help of 170+ mental health experts to improve how ChatGPT responds in sensitive moments—reducing the cases where it falls short by 65-80%. https://t.co/hfPdme3Q0w
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Earlier this month, we updated GPT-5 with the help of 170+ mental health experts to improve how ChatGPT responds in sensitive moments—reducing the cases where it falls short by 65-80%. https://t.co/hfPdme3Q0w
openai.com
We worked with more than 170 mental health experts to help ChatGPT more reliably recognize signs of distress, respond with care, and guide people toward real-world support–reducing responses that...
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Agency > Intelligence I had this intuitively wrong for decades, I think due to a pervasive cultural veneration of intelligence, various entertainment/media, obsession with IQ etc. Agency is significantly more powerful and significantly more scarce. Are you hiring for agency? Are
Intelligence is on tap now so agency is even more important
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What people don't realize about AI creative tools: For many users, making things with AI has become a hobby and/or a form of entertainment. This is like asking why people pay money to stream TV, go to a show, or join a soccer league. It's just fun!
Can someone explain where this revenue comes from? Who's paying?
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What the outside world largely does not understand about OpenAI is how decentralized and bottom-up it is, and why this is incredibly good and important for the democratization of benefits. Aidan explains it well.
@nearcyan i think your error here is thinking sora and adult content are some leadership master plan; that sama sat down with accountants and signed and said “it’s time to break glass for emergence revenue” no. i know the exact people who pushed for sora, they’re artists who worked
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@nearcyan i think your error here is thinking sora and adult content are some leadership master plan; that sama sat down with accountants and signed and said “it’s time to break glass for emergence revenue” no. i know the exact people who pushed for sora, they’re artists who worked
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AI is set to help unlock biology at unprecedented speed, and we need this acceleration to yield more cures than threats Proud to back @kath_mcmahon and @ValthosTech to redefine biodefense for the AI era !
Valthos builds next-generation biodefense. Of all AI applications, biotechnology has the highest upside and most catastrophic downside. Heroes at the frontlines of biodefense are working every day to protect the world against the worst case. But the pace of biotech is against
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always love the chance for a casual chat with @tbpn about the looming risk of AI-enabled biothreats :)
.@kath_mcmahon on the asymmetric nature of biodefense: —Much easier to make a pathogen than it is a cure —Skill set to engineer pathogens dropping week over week —Threat used to be sophisticated state-sponsored programs. Now it looks like a couple students at the grad level.
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Spent three years looking for a team in Biodefense to invest in. But never found one. So we built it ourselves. Valthos builds next-generation biodefense. As AI and biotech rapidly advance, we're approaching near-universal access to tools with the potential to cure humanity or
Valthos builds next-generation biodefense. Of all AI applications, biotechnology has the highest upside and most catastrophic downside. Heroes at the frontlines of biodefense are working every day to protect the world against the worst case. But the pace of biotech is against
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We've raised $100M from Kleiner Perkins, Index Ventures, Lightspeed, and NVIDIA. Today we're introducing Sonic-3 - the state-of-the-art model for realtime conversation. What makes Sonic-3 great: - Breakthrough naturalness - laughter and full emotional range - Lightning fast -
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If you're thinking about biosecurity or inspired re: AI safety more broadly, Mike is the man to talk to!
Totally agree. Excited to see more biodefense / biosecurity companies. Congrats @ValthosTech on the launch!
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Excited that such a great team is working on this. Addressing an ever-expanding attack surface will be a critical to building a secure AI-enabled bioeconomy. If this interests you, definitely reach out to the @ValthosTech team — there’s no time like the present!
Valthos builds next-generation biodefense. Of all AI applications, biotechnology has the highest upside and most catastrophic downside. Heroes at the frontlines of biodefense are working every day to protect the world against the worst case. But the pace of biotech is against
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1/ I spent a long time at Palantir chasing hard problems with brilliant people (can recommend). So I think I know a good quest when I see it. Excited to announce that I started Valthos with @velvetatom and an incredible team
Valthos builds next-generation biodefense. Of all AI applications, biotechnology has the highest upside and most catastrophic downside. Heroes at the frontlines of biodefense are working every day to protect the world against the worst case. But the pace of biotech is against
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I’ll be on @tbpn at 4:05 ET / 1:05 PT to chat about @ValthosTech and what we’re building for American biodefense! 🇺🇸🇺🇸
Gm. On today’s show: – @esaagar (Breaking Points) – @jordanschnyc (ChinaTalk) – @ChaseLochmiller (Crusoe) – @TuckerDordevic (Oureon) – @kath_mcmahon (Valthos) – @Dion2730 (NVIDIA) – @burkaygur (Fal) – @glennsolomon (Notable Capital) – @asciidiego (Krea) – @venturetwins (a16z)
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Congrats to Olivia and the Valthos team. It’s awesome to see smart people working on such a critical and neglected ted problem. In order to reap the benefits of AGI, we need secure deployment. Very excited to see what Valthos does in this space.
Today, @ValthosTech launches with $30M from @Lux_Capital, @OpenAI, and @foundersfund. For the past few months I’ve been working with their world-class team (@MIT, @GoogleDeepMind, @PalantirTech) building America’s modern next-gen infrastructure. Hiring –– DM me.
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Announcing Lux latest investment and creation.... BIODEFENSE @ValthosTech —co-founded by Lux's @velvetatom Tess Van Stekelenburg + led by brilliant ex Palantir @kath_mcmahon
Valthos builds next-generation biodefense. Of all AI applications, biotechnology has the highest upside and most catastrophic downside. Heroes at the frontlines of biodefense are working every day to protect the world against the worst case. But the pace of biotech is against
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One of the greatest opportunities in AI safety and security is the chance to help support the creation of new industry verticals that help maximize the benefits and minimize the risks. The technology is moving fast. One of the best ways to keep up is with more technology, more
Valthos builds next-generation biodefense. Of all AI applications, biotechnology has the highest upside and most catastrophic downside. Heroes at the frontlines of biodefense are working every day to protect the world against the worst case. But the pace of biotech is against
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