🍤 time! In this new pre-print we used ultra-strong gradient dMRI to investigate the neurite and soma development of the hippocampus in childhood and adolescence. "The developing hippocampus: Microstructural evolution through childhood and adolescence":

Excited to be giving a talk on @afids_project as part of #OHBM2024's #Neuroinformatics session (6/25 @ 12PM🇰🇷; GB 103) Come 👀 how we're: ➡️pooling 20K+ community curated 🧠 landmarks to 📏 registration accuracy 🎯 and for #QC ➡️creating resources/apps to simplify this process

🔊Announcement🔊! The @neuroak & @jclauneuro labs are 𝙝𝙞𝙧𝙞𝙣𝙜 𝙩𝙬𝙤✌️𝙧𝙚𝙨𝙚𝙖𝙧𝙘𝙝 𝙨𝙤𝙛𝙩𝙬𝙖𝙧𝙚 𝙙𝙚𝙫𝙚𝙡𝙤𝙥𝙚𝙧𝙨 in basic + translational neuroimaging @WesternU.🧠🔭 Supported by @TRIDENTPCT @Brains_CAN. https://t.co/dPheXyh4RS [Job ID: 35643 + 35752] #ldnont 🇨🇦

Arun Thurairajah will present Labelmerge, a @BIDSstandard app for a user-friendly and more efficient method of combining parcellations from multiple brain atlases. Poster 2493 #OHBM2023 6/

@jasonkai @alaa_t_ The zona incerta has been called an “immensely confusing area about which nothing can be said." @jasonkai @royhaast et al have characterized its connections using in vivo 7T MRI diffusion data applying both clustering and gradient approaches. Poster 0384 #OHBM2023 9/

@BIDSstandard Interested in reliably & reproducibly identifying connections between brain regions? Check out SCATTR, a workflow developed by @jasonkai et al to identify the subcortical connectome https://t.co/1CuOOpW7hp, now available as a @BIDSstandard app. Poster 0333 #OHBM2023 7/

Cerebro is getting documented... ...a gallery of possible visualisations are to come 🌌 Kudos to my wonderful brainhack buddies, @jaysonjeg @jasonkai @TristanKOpenSci @psychinthecity_ @AnnieGBryant #OHBMBrainhack #BuddySystem https://t.co/3BecyYiaoC

https://t.co/ALEC9si3KG We find limited abnormalities in frontal "U"-fibres in untreated #schizophrenia using 7T diffusion MRI. Adds to studies showing meagre white matter changes in first-episode #psychosis. With Jason Kai @neuroak's team @WesternCFMM

Excited to announce our @afids_project data release! 19,000+ manually placed brain landmarks across multiple templates and datasets, comprising 300+ human rater hours of annotation over 4 years! Preprint: https://t.co/vS45CJBTMH #openscience #stereotaxy #neuroanatomy #QC 1/n

Mapping the subcortical connectome using in vivo diffusion MRI. Now published in @NeuroImage_EiC: https://t.co/1CuOOpW7hp Led by @jasonkai + @RoyHaast @neuroak. 🧠🔍🗺️ Using @HumanConnectome data, and supported by @Brains_CAN, @NSERC_CRSNG, @WesternUCNS, @ComputeCanada.

Come see how structure-function coupling changes following temporal lobe epilepsy surgery @OHBM (WTh237)! #OHBM2022

Interested in the hippocampus and it’s microstructure? Come see our poster (WTh257) at #OHBM22 @neuroak @jordandekraker

Swing by poster WTh795 to learn more about our investigation into the reliability & feasibility of recapitulating the subcortical connectome in vivo using tractography. #OHBM2022

Thanks for reading this far! We would welcome feedback on this work. Thanks to support from @Brains_CAN @westernuCNS @ComputeCanada @NSERC_CRSNG @CIHR_IRSC 7/7

The methods used were developed using an open framework that we anticipate will be helpful for further improvements in both the accuracy and reliability of computed subcortical connectomes. 6/7

Not only could we identify most known subcortical connections, but we could also identify them reliably by applying our methods to both the test-retest and unrelated subsets of HCP. 5/7

Using probabilistic tractography together with subcortical ROIs, we were able to successfully recapitulate most of the known connections of the human subcortex. e.g. the ansa lenticularis connecting the GPi and VLp. 4/7

Investigations of this circuit in vivo have so far been limited due to the difficulty of performing tractography in this complex and compact region... providing motivation for us to assess this possibility by leveraging data from the Human Connectome Project (HCP). 3/7

Classic studies have identified an intrinsic circuit involving connections between key nodes of the subcortex. See this schematic and article by Delong et al. for a great review. https://t.co/2MyLwYpUkT 2/7

Excited to share our preprint investigating in vivo diffusion MRI for mapping connections between subcortical structures, that is, the subcortical connectome. w/ @neuroak @RoyHaast @jclauneuro https://t.co/jzd8JwQ6QS 1/7