Jakob Jung
@jakobjung
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➡️ https://t.co/0x051fans3 🦋 https://t.co/3HwHCi2MKF 🦋 comp. biologist, species-specific antibiotics. (he/him)
Joined January 2013
Happy to share my 1st 1st-author publication! .Our experiments reveal mismatch-position dependency of antisense-PNA #antibiotics. We Included this in MASON, a web-based PNA design tool. Big thanks for the support of the co-authors/helpers from @LBarquist @JoergLab @Helmholtz_HIRI.
The MASON webserver offers improved design of RNA-targeting antisense antibiotics, taking account of position-dependent effects of mismatches on target bacteria
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RT @FEMSmicro: Turning E. coli into a comic-book hero or villain🦸♀️🦹♂️🦠.Gozzi et al. show how the Adopt-a-Bacterium method lets biomed st….
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The most fun image & video creation tool in the world is here. Try it for free in the Grok App.
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RT @Helmholtz_HZI: Wir stellen unsere Aktivitäten auf X ein. 👋.Updates zu unserer Forschung und der Welt der Infektionsforschung findet ihr….
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RT @Leseerlaubnis: Die Rede von Kevin Kühnert müssen alle Menschen hören. Eine Rede mit historischer Bedeutung.
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RT @FEMSmicro: Now, more than ever, we must embrace #diversity, #equity, and #inclusion in education. A #FEMSMicrobiolLett article explor….
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RT @MCaraggiu: Der #Wahlomat ist da. Die Bundestagswahl steht vor der Tür und gerade mit den Ereignissen der letzten Woche hat mich die Übe….
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RT @PatrickBohnPB: Interested in multiplexing samples for nanopore dRNA sequencing with the new chemistry? Check out our newly released RNA….
github.com
Highlights 🎉 Full RNA004 Support with the WDX4 model, achieving 99.5% target accuracy at 95% yield. Features barcode-specific target accuracy confidence score filtering for optimal performance....
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RT @NatureMicrobiol: Emergency bulletin! 14 journals have co-published an urgent call for the deployment of microbial solutions against cli….
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RT @mgalactus: We used in-vitro laboratory evolution to "stress test" the next generation class of antibiotics based on antisense oligos ("….
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RT @paramita_srkr: I am excited to finally share this preprint from @JoergLab. We've developed a reporter assay to enable high throughput….
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RT @abaumler: How do you distill #microbiome complexity into ecologically meaningful units? . Clear away the confusion with MICROBIOME FO….
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RT @UliKluemper: This is big!. Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050….
thelancet.com
This study presents the first comprehensive assessment of the global burden of AMR from 1990 to 2021, with results forecasted until 2050. Evaluating changing trends in AMR mortality across time and...
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RT @IntMicroDay: Happy #InternationalMicroorganismDay to everyone celebrating across the world! 🌐. It's only with such a devoted community….
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RT @JoergLab: Shall we start calling them „asobiotics“? Probably easier than „antisense-based antibiotics“ or „antibacterial peptide-delive….
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RT @Helmholtz_HIRI: 🚨 New paper alert! 🚨 Check out the latest publication from @LBarquist's lab in @mbiojournal! Huge congratulations to al….
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RT @EvolvedBiofilm: High-throughput transposon mutagenesis in the family Enterobacteriaceae reveals core essential genes and rapid turnover….
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RT @LBarquist: We determined gene essentiality in 13 Enterobacteriaceae including E. coli, Salmonella and Klebsiella strains, and find ~1/3….
journals.asm.org
The essential genome, that is the set of genes absolutely required to sustain life, is a core concept in genetics. Essential genes in bacteria serve as drug targets, put constraints on the engineer...
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RT @MazzucatoM: The big consultants haven't just benefited from a weakened state - they've championed an ideology of short-termism and risk….
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RT @JoergLab: ASO technology using exogenous delivery of antisense oligonucleotides offers many diverse applications, from killing pathogen….
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RT @PatrickBohnPB: Finally, meet WarpDemuX! . Our (@wiepp) solution for dRNA multiplexing - so fast it runs on any laptop, and so accurate….
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RT @mgalactus: Do you want to run a microbial GWAS but are put off by installing a dozen different bioinformatic tools, are unsure about be….
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