Islet Biology Lab - UMH
@isletbiologylab
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We're interested in islet cell function and survival in #type1diabetes. Headed by @lmarroqui and @rsdossantos13. @UnibadUMH/@IDiBE_UMH/@ciberdem/@GVAfisabio
Elche, Spain
Joined March 2020
🚀Exciting news! @MetabologiaJnl , our newest open-access journal and sister journal to @DiabetologiaJnl, is accepting submissions. Publishing research on diabetes, #obesity , metabolic disorders, and more. 📝 Learn more and submit: https://t.co/5g2Q4JHs3h
#Diabetes #Research
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Las áreas de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM) y de Enfermedades Hepáticas y Digestivas (CIBEREHD) de nuestro @CIBER_ISCIII han celebrado en Sevilla está semana su I Reunión Científica Conjunta 👏 ➡️
Aquí está la foto de familia de las I Jornadas Científicas Conjuntas #CIBERDEM 🤝 #CIBEREHD ¡Sigamos colaborando! 👏
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🔬Applications are now open for the #EFSD & #novonordisk A/S Programme for Diabetes Research in 🇪🇺. Open to researchers at non-profit institutions working on innovative #diabetes projects. 📅 Deadline: 2 Feb 2026 Apply now 👉 https://t.co/rx2IH5XEfw Supported by @novonordisk
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Se están celebrando las jornadas conjuntas entre #CIBERDEM 🤝#CIBEREHD en Sevilla Estas dos áreas se unen para avanzar en la investigación de la diabetes, enfermedades metabólicas, hepáticas y digestivas 🔎 ➡️ https://t.co/EY4iVFZk2C
#CIBER #jornadas
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Kicking off the First CIBERDEM-CIBEREHD Joint Scientific Meeting. Let’s get started. 🚀
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Our new paper is out now in Nature Communications! We uncovered the function of XBP1 in beta cells of a preclinical model of T1D and identified unique and shared gene regulatory networks driven by IRE1 and XBP1. https://t.co/nYNFaLP8sD
nature.com
Nature Communications - Modulating the unfolded protein response (UPR) can induce protective dedifferentiation of β-cells in non-obese diabetic mice. Here, the authors show that β-cell...
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Abedi et al. conducted a comprehensive analysis of gene expression and chromatin accessibility in immune cells from the pancreatic lymph nodes and spleens of individuals with and without #type1diabetes. https://t.co/jUGHJ04t0U
science.org
Joint chromatin accessibility and transcriptomic profiling of human and mouse pancreatic lymph nodes uncovers distinct features of CD4 T cells in T1D.
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Repeated anti-CD3 dosing in new-onset #Type1Diabetes: no added benefit. ✅ Safe and well tolerated, but extra cost and effort bring no gain. #Immunotherapy #T1D #DiabetesResearch #Research #OpenAccess #Science
https://t.co/5rrcQhbnoy 🔓
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Nguyen et al. identified a novel ROS-Ca2+ overload-mTORC1 cytopathic mechanism that underlies impaired autophagy and proposed various protective strategies to correct or relieve pathogenic alteration in β-cell lipotoxicity. https://t.co/Jsof96dMBK
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Professor Matt Webber is working to make insulin smarter. We spoke with him about how his work designing these insulins could help ease daily life for people with type 1 diabetes. Read the full interview: https://t.co/8rmKES6xNI
@BreakthroughT1DUK #Type1DiabetesGrandChallenge
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El proyecto SINERGYxDM2 financiado por @FundacionAZ ha recibido el premio a la Transferencia de Conocimiento #IPfest2025. La investigadora de nuestro grupo, Izortze Santin, ha recibido el premio en Bilbao en nombre del equipo de investigación @MerinoAntolin @AMartinMontalvo
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🔬 España es líder europeo en ensayos clínicos… pero solo participa en 4 estudios activos en diabetes tipo 1, ocupando la 10ª posición en Europa. Un área clave donde aún tenemos una gran asignatura pendiente. 📄 Informe completo de @diabetes_CERO : https://t.co/WyJSmsNolL 🧵
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Frørup et al. aimed to evaluate cathepsin S as a treatment target in type 1 diabetes by examining the effects of oral administration of the potent and selective Ctss inhibitor LY3000328 on autoimmune diabetes and glucose tolerance in the NOD mouse. https://t.co/7gaO2F37LD
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🎉New study from our lab on circulating SASP factors suggests a novel senescent cell biomarker across #T1D stages! Congrats🥳Camille @pipellaj and @DREAM_trainees Grateful for @T1D_TrialNet 🙏🏿 @DREAM_diabetes @CIRTNetwork @CHRIManitoba
nature.com
Scientific Reports - Circulating senescence-associated secretory phenotype factors across the stages of type 1 diabetes in a cross-sectional cohort
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Wong et al. provide a historical perspective, particularly highlighting areas of progress in understanding aspects of aetiology and immune pathogenesis, and utility in helping to shape the immunotherapeutic landscape. https://t.co/RTXcGr03Yy
link.springer.com
Diabetologia - The NOD mouse is the best-known, although by no means the only, murine model of type 1 diabetes. In this review, we provide a historical perspective, particularly highlighting areas...
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⏳There is still time to apply for the 2nd @EASDacademy Meeting, held from 30 March to 1 April 2026 in Düsseldorf. ⏰ Application Deadline: 2 December 2025 Explore the programme and submit your application 👉 https://t.co/GwwfcpCCBy
#EarlyCareer #Diabetes #DiabetesCare
📣Final weeks to apply for the 2nd Early Career Academy Meeting! A 3-day programme for early-career researchers to learn, collaborate and connect with diabetes experts. 📅 30 March - 1 April 2026 |📍Düsseldorf ⏰ Deadline: 2 December 2025 Apply now👉 https://t.co/lgUCwlG6Rc
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