Invivyd
@Invivyd
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Invivyd is improving lives with medicines for serious infectious diseases. #mAb #covid19
New Haven, CT
Joined July 2020
A bubbling measles outbreak in the upstate of South Carolina has forced 153 unvaccinated children out of the classroom and into quarantine for a minimum of 21 days.
nbcnews.com
At least 270 unvaccinated kids are staying home from school as measles continues to spread nationwide. "Expect more," one expert said.
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The extraordinary ongoing burden of COVID is so easy to see if you look, and - apparently - so easy to not see if you don’t look. If we want to all live longer and better we probably need to start looking more!
COVID didn’t end - it changed the baseline of how often people fall ill, miss work, and drop out of the labor force. A new JAMA study shows the US now lives in a permanent flu-season mode, all year round🧵
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We have received IND clearance and alignment with US FDA on a pivotal clinical program for our investigational antibody VYD2311. Read about it & our clinical program, REVOLUTION, here
investors.invivyd.com
The DECLARATION (safety and efficacy vs. placebo) and LIBERTY (exploratory safety head-to-head and combination with mRNA-based COVID vaccination) clinical trials are expected to begin around year-end...
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Amazing and sad that questions are being asked of *patients* about Americans thinking “COVID is over”. It’s probably offensive to someone suffering, and there sure are a lot of people suffering. Pandemics can “end” when people or Presidents arbitrarily say they are. The word
It’s been more than two years since the pandemic ended, but millions of Americans are still living with long COVID. That’s a catchall term for COVID symptoms lasting at least three months after first testing positive. Symptoms can vary from person to person, but they range from
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Like many organs that require glucose and oxygen, the brain is sensitive to vascular function, which is of course assaulted by SCoV2 around the entire circulatory system. So in terms of systems marked “safe” from COVID vascular dysfunction, we are maybe down to what -
A new UK Biobank study found COVID survivors aged 50+ had a higher risk of new-onset dementia vs uninfected controls. Among 54,757 participants followed for 24.1 months, prior infection was linked to a 41% increased risk. https://t.co/Y61kVPdUnA
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We warned about thrombotic endothelialitis, microclotting and platelet hyper-activation since the start of the pandemic. We provided the evidence: look in the blood. If you had Covid, you are at risk. With every new infection you are at risk to develop LongCOVID.
At a WHO briefing in 2022 we publicly warned of a tsunami of cardiovascular disease caused by Covid if we opened up countries without clean air & other PH mitigations in place first. Instead “Let it Rip” was adopted by most countries…….1/2
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In 2022, an economic researcher for the Federal Reserve Bank of New York wrote an article about LongCOVID causing a surge in disability and becoming a workplace fixture. Citing Census Bureau data, the CDC and NIH, he suggested future COVID waves could continue disabling workers.
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“F’d” seems to sum up the overall population health trajectory nicely when considering pervasive SARS-CoV-2. Time to drive some meaningful, scalable changes in protection and treatment! (we will log off and get back to work now!)
If you haven't read The Great Influenza by John Barry (I did, March 2020) Now would be a good time to pick it up. FWIW, we are F'd if we don't change the strategy now.
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A public health disaster playing out. We must do more!
New study in The Lancet Infectious Disease analyzing 460,000 patients across 40 US hospitals found that children’s risk of developing LongCOVID more than doubled upon reinfection, with no significant variation by vaccination status.
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One of the largest measles outbreaks in the U.S. is now centered in bordering areas of southwestern Utah and Arizona.
nbcnews.com
Measles vaccination rates have plummeted in the neighboring communities over the last 10 years.
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A worthy perspective from humanist extraordinaire, Dr. David Putrino. The Long Covid world is stronger for his convictions and clarity!
A few days out from #UNGA80, I wanted to reflect on the session we took part in and the media responses since. Mount Sinai was one of the 150 organizations that signed the global pledge to advocate for healthy indoor air. The event itself featured four panels of speakers who 1/
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Hard to pin these trends on a year of virtual school or toilet paper shortages
If Covid really was causing long-term illness and disability in the population, there would be signs. The signs…👇👋 🚨 #LongCovid #MassDisablingEvent
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We are thrilled to welcome @PaulBolno to Invivyd's Board of Directors. Dr. Bolno is the President and CEO of the innovative biotech company, Wave Life Sciences, and he is an expert in developing new medicines to keep people healthy. Please read the press release for more
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We, as a species, can be *both* relieved that not as many people die horribly in isolated hospital wards as they once did *and still* totally intolerant of the ongoing immunologic, thromboembolic, and vascular / end organ damage being created by a lab-leaked virus running free in
A massive new peer-reviewed review (161 studies, 2+ million patients) makes it clear. COVID-19 isn’t just a respiratory infection. It’s a multi-system disease leaving lasting scars on lungs, heart, brain, kidneys, and more.🧵
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There’s a lot of life to go live while we all can, and Covid doesn’t make any of it better to our knowledge. Stay healthy so you can pursue joy and fulfillment! Amen!
Fundamentally, the reason I avoid Covid is because all - all - of the elements of my life that bring me joy and fulfillment rest on my cardiovascular fitness and / or my cognition. I'm not going to risk a virus wrecking that, as I've seen happen to way too many people I know.
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On Wednesday, members of the Invivyd team had the privilege of attending an @mssociety luncheon in Pittsburgh. Listening to a patient share her journey was a powerful reminder of the challenges people living with MS face every day, and why the patient voice matters so much.
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Caution, findings like these may present intellectual / emotional challenges to the many people who do elaborate diet, supplement, and exercise routines to “minimize inflammation” and enhance wellness while telling you that COVID is no big deal and just a cold.
COVID-induced neuroinflammation can last 2 years or longer, according to new PET data #LongCovid
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Society of Actuaries report on COVID cause specific excess mortality published in Dec 2024 is an eye-opener. These are the guys that follow the money. Things that stood out for me: Covid 19 deaths underreported and mis classified as natural deaths (that are related by
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Endothelial dysfunction sounds so abstract until you learn enough about the endothelium to realize it is perhaps your most important long-term contributor to being healthy and alive
Months after COVID-19, many people still show signs of blood vessel damage, known as endothelial dysfunction. This hidden issue can quietly increase the risk of long-term heart and vascular disease. https://t.co/KCd6TMCFiF
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COVID-19 survivors face lasting cardiac risks due to inflammation, endothelial damage, and microvascular injury. These changes cause diastolic dysfunction, arrhythmias, and may accelerate or trigger heart failure with preserved ejection fraction. https://t.co/Z3eDDbR6Zo
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