Luke Pattison
@interlukein
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Research scientist interested in inflammatory pain 🔬 👨🏼🔬 ✌🏼
Cambridge, England
Joined November 2016
If you have #osteoarthritis which causes you #pain, please consider answering my 2 minute survey below 👇.
👋I’m developing a proposal to investigate how pain changes with progression of osteoarthritis (OA). 🦴⚡️. If you have OA, I’d love to hear how your experience with pain has changed over time - please consider answering this quick 10-question survey! 🙏.
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👋I’m developing a proposal to investigate how pain changes with progression of osteoarthritis (OA). 🦴⚡️. If you have OA, I’d love to hear how your experience with pain has changed over time - please consider answering this quick 10-question survey! 🙏.
forms.office.com
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RT @MSKPainCenter: New preprint from the lab: Targeting piezo2 to treat osteoarthritis pain.
biorxiv.org
Musculoskeletal pain is a significant burden affecting billions of people with little progress in the development of pharmaceutical pain relief options. The mechanically-activated ion channel Piezo2...
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RT @interlukein: 📣 Calling fellow ECRs studying the contributions of GPCRs to pain and/or analgesia!. 🧠 Interested in presenting at #SfN25….
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📣 Calling fellow ECRs studying the contributions of GPCRs to pain and/or analgesia!. 🧠 Interested in presenting at #SfN25 in San Diego in November? . 🙏 Please drop me a message - looking for last few speakers for a mini symposium proposal!. #PainResearch #Neuroscience.
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Exciting project, great mentor, lovely Cambridge - get applying!.
🚨 Excited to announce that we are hiring 🚨. If bowel disease, pain, & naked mole-rats are your thing then we have the perfect opportunity for you 😃. This @ChatGPTapp image shows a naked mole-rat with visceral pain, but they actually appear resistant #PainResearch
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Research Showcase of our latest work investigating the role of acid-sensitive receptors in inflammatory joint pain! 💊.
growkudos.com
Inflammation is often linked to increased acidity in tissues, which can activate specific receptors such as GPR65. In this study, we found that activation of GPR65 in cells lining the knee joints of...
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Very happy to share the published version of this work - out now in @PNASNews - riding the year out on a high! ✨. More on this work below 👇.
pnas.org
Inflammation is associated with localized acidosis, however, attributing physiological and pathological roles to proton-sensitive receptors is chal...
Very happy to share our ✨ NEW ✨ preprint!. Activation of the proton-sensing GPCR, GPR65 on fibroblast-like synoviocytes contributes to inflammatory pain. Keep reading for a summary of what we found… 🧵[1/10].
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Excellent tweetorial describing our latest work, looking at lipids and inflammatory joint pain 👇.
Pain = main driver of clinical decision making in osteoarthritis (OA). Our lab studies OA pain mechanisms. During OA, multiple cell-cell interactions occur, many mediators being released that alter the contents of the synovial fluid. #neuroscience #pain.
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RT @Alleviate_Data: Through #PainAwarenessMonth we are collecting the 3-words that best describe your pain and creating a word cloud of the….
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Are you living with #ChronicPain? Have 15 minutes to spare? Please consider completing the UK National Pain Survey? Get your voice heard and shape the future of pain research! 🙏.
Alleviate & partners @ChronicPainAust @Pain_UK @MsApdp launch 2nd UK National Pain Survey! Share your lived experiences of chronic pain & help inform research. Complete the survey today: #PainSurvey2024 #PainResearch #YourVoice .@UoDMedicine @HDR_UK
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RT @IASPpain: @interlukein et al. find that deficits in mouse digging behaviors resulting from pain models correspond well with how humans….
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We made the front page!! 🤩🤩.
PAIN’s Aug cover: Mouse colon sections show DSS-concentration-dependent immune cell infiltration & colon structure loss. Digging behavior correlated with colitis severity, suggesting a relevant pain phenotype. More in @interlukein et al.’s article in #PAIN
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Heading back to the lab after an inspiring few days at the 4th iGPCRnet meeting, hearing about the latest and greatest in GPCR research! 💫
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Sad to have missed this, but know Niall will have smashed it! 🤩 Looking forward to reading the thesis!.
Next up Niall Summers @downingcollege from @psalmotoxin working with @interlukein @UnivCamPharm ‘characterising proton sensitive GPCRs GPR31 and GPR151’
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Excited for this chance to talk about our latest work next week - see you at The Cambridge Tap! 😉 🍻.
@interlukein from @UnivCamPharm studies pain, something we still struggle to treat effectively 🤕. How can we find new drug targets? He'll discuss one in particular, an acid-sensing receptor, and its role in joint pain 🦵
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RT @CamBrainCNS: Don't miss the last Neurotalks before our summer break! 🌞 We're finishing on a high with neuropharmacology 💊 - speaker and….
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