Think of transplanting stem cells like sending an athlete onto the field—without training, they'll struggle. @AliaAliyyaa and @QiushengShi created a "warm-up" system that mechanically pre-trains MSCs for the knee! @Benjamin16939554 @Lisha00233648 🔗 https://t.co/fbJKjA7CzG

Latest from @CHESM_unimelb …..what are the most important research priorities in PA/exercise therapy for hip/knee #osteoarthritis?

🏋️‍♂️What are the research priorities of consumers, clinicians and researchers for the physical activity and exercise management of knee and hip #OA? Find out more in this new paper by @KimBennell @HinmanRana et al - https://t.co/vfmvXYQaaO

Link to paper published in @OACJournal here:

👀 NEW study that found a protective effect of free hashtag#testosterone for chronic knee pain BUT only in females Read more from Szilagyi et al. - https://t.co/7VGAgJwcnq

🆕 Largest global review (>130 studies and risk factors evaluated) of risk factors for knee #osteoarthritis (KOA) identifies obesity, knee injury & occupational risks as targets for future prevention strategies 🔓 Read free from @vickyduong et al. - https://t.co/LJg5AbGqeQ

https://t.co/VUwrPKwSHN

The sphingolipid sphingomyelin 34:1 is upregulated in the synovial fluid during OA. This study shows that SM34:1 causes inflammatory pain in mice and induces neuronal hyperexcitability. Great work: @psalmotoxin @interlukein @mayadannawi @LanhuiQiu @BeckyRickman @UnivCamPharm

Are you a creative scientist?🧐 #OAC is looking for a new cover design! Submit your Osteoarthritis and Cartilage based cover designs by November 10th, 2025🤩 https://t.co/edgTpdqX0n

#New this month in #OAC . Translocator protein 18 kDa (TSPO) plays an important role in #OA occurrence and development. Emapunil targeting TSPO improves OA by modulating #macrophage polarization and #inflammation through the CD14/TLR4/LY96 pathway. 🔗 https://t.co/O21z3iHnGf

#New in #OAC This study by Xiao et al. demonstrates that YAP plays a critical role in subchondral bone remodeling and targeting the YAP-Hhip axis through regulation of Hh-Gli1 signaling in Gli1+ osteogenic progenitors could inhibit OA progression! 🐭 🔗 https://t.co/zPtDcZgAaV

This week on Joint Action, we honour Prof. Frank Beier and his extraordinary contributions to #osteoarthritis. Frank joined us in 2021 for an insightful conversation — a discussion that continues to inspire researchers and clinicians alike. Listen at https://t.co/EBhy6Fcuq4

Interested in the most important research priorities for exercise/physical activity in knee/hip OA? Read the latest work led by the @OARSInews Rehab Discussion Group.....published in @OACJournal @CHESM_unimelb https://t.co/xJwRrnKCoY

⌛ New this month! ⏰ Read all about hashtag#epigeneticclocks as promising biomarkers for hashtag#osteoarthritis and degenerative musculoskeletal diseases here - https://t.co/aCaqeSBP65

🌟 Four other conditions that should be considered in the differential diagnoses of early-stage symptomatic knee #osteoarthritis (EsSKOA) 1️⃣ Patellofemoral pain 2️⃣ Meniscus injuries 3️⃣ Collateral ligament injuries 4️⃣ Inflammatory arthritis Read free at https://t.co/TGlbpbnBX3

Ultra-processed foods (UPFs) are created using industrial techniques, chemically modified substances from foods, and additives. They contain little to no, whole foods 🚫 On Joint Action, we talk about the link between UPFs & #osteoarthritis 🍟 🎧 https://t.co/RBaoTwtHEY

Participants whose daily activity best matched patterns of high evening activity or very high morning activity had the least risk of developing #slowgaitspeed 🚶‍♂️ 🗞️ Read more from Tore et al. https://t.co/5Z6PwloSE8

#BasicScience #EditorsChoice This work by Liao et al. investigated the effects of Tamoxifen in multiple mouse models to better understand its role on bone and cartilage metabolism and endochondral ossification. 🐭 📖Read more: https://t.co/MfY4V4BCW3

🎙️ Also join co-author Gabby Joseph and @ProfDavidHunter on a more in-depth discussion on this topic on this new @jointactionorg podcast https://t.co/yHpnRCoUo1

NEW in this month's issue 🔥 September's Editors Choice by Akkaya et al. found that diets rich in ultra-processed foods are linked to worse knee #osteoarthritis outcomes especially in women 🍔🍦🍟🍩 👀 Read about this large (n=4403) study for free at: https://t.co/JrxkfE2yZ0