Honi Sanders
@honisanders
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Neuroscience Postdoc - hippocampus, computational, learning Building models of model-building
Joined January 2019
figure 5 is absolutely unbelievable. i have never seen a simulation capture more independent features of the results of an experiment.
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A scientist critic was sued, and won — but did not emerge unscathed. This is his story.
retractionwatch.com
David Sanders Retraction Watch readers may be familiar with the name David Sanders. Sanders, a biologist at Purdue University, has become a scientific sleuth, ferreting out problems in numerous pap…
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interesting perspective. downthread discussion of how that plays out in policy.
One of the best pieces of advice I ever got, delivered by a wise person while I was fuming over a parking ticket: . "3% of your income is for mistakes. If it's too much over, you're too sloppy. If it's too much under, you're sweating the smalls stuff too much.".
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Excellent work providing evidence for the Hidden State Inference framework proposed in our 2020 eLife paper. The figures in this paper are beautiful. Check out their supplemental figures for an even more compelling review of the morph box literature.
I am very excited to share the main project from my graduate work with @lisa_giocomo that is out in @NatureNeuro today! Hippocampal place cell remapping across environments might simply reflect the animal's best guess of the environment identity. This guess depends on experience.
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RT @AnneEUrai: Training 🐭 to do behavioral tasks? Looking for an alternative to water restriction? .Want to improve your own work-life bala….
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lololol. a scam artist gets his comeuppance.
Carlo Croce, a scientist at @OhioState who has lost two libel suits, has now been sued twice for unpaid legal bills >$1.5 million. Turns out that one set of attorneys only agreed to represent him if he used his house as collateral. Thread.
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If you didn't make it, you can find the preprint on BioRxiv
biorxiv.org
Hippocampal place cells form a map of an animal’s environment. When the animal moves to a new environment, place field locations and firing rates change, a phenomenon known as remapping. Different...
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Presenting at Virtual SfN. Animal-to-Animal Variability in Hippocampal Remapping. Co-authored with @NilchianParsa and Matt Wilson.
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New work with an outstanding undergrad, Parsa Nilchian. "Heterogeneity in animals’ remapping behavior is structured: animals’ remapping behavior is consistent across a range of independent comparisons. Remapping between environments depends on animal-specific factors.".
Animal-to-Animal Variability in Hippocampal Remapping #biorxiv_neursci.
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Just published a Preview: describing the work of @jcrwhittington and @behrenstimb in creating the Tolman Eichenbaum machine.
Hello! Very happy to share that The Tolman-Eichenbaum Machine (TEM) has been published. Many thanks to @behrenstimb and my other co-authors @TimMuller1,@ShirMarkLey,@GuifenChen,@caswellcaswell, @NeilBurgess10 for their help and support along the way! 1/15
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really solid implementation of a network that can learn to transfer relational structure between different environments, even for non-spatial relationships!.
Hello! Very happy to share that The Tolman-Eichenbaum Machine (TEM) has been published. Many thanks to @behrenstimb and my other co-authors @TimMuller1,@ShirMarkLey,@GuifenChen,@caswellcaswell, @NeilBurgess10 for their help and support along the way! 1/15
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Popular press explainer of my recent @eLife article.
What prompts the brain to create a new map of the environment? In a recent @eLife study, @honisanders, Prof. Matt Wilson, and @gershbrain suggest “remapping” can be mathematically modeled as a feat of probabilistic reasoning. Via @MIT_Picower:
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Relates to empirical findings ranging from Experience-dependence of remapping to Morph experiments to Partial/Rate remapping to Animal variability.
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"According to this view, remapping does not directly reflect objective, observable properties of the environment, but rather subjective beliefs about the hidden state of the environment.".
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Hippocampal Remapping as Hidden State Inference -- Theory paper co-authored with @gershbrain and Matt Wilson out in @eLife! .
elifesciences.org
Context representation in the hippocampus incorporates uncertainty and requires inference based on past experience.
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