Holubcova_lab
@holubcova_lab
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Research group of human gametogenesis and early embryogenesis @Science_MEDMUNI
Brno, Česká republika
Joined January 2021
We are recruiting! If you are like us passionate about oocytes and early embryo development join us @Science_MEDMUNI @MasarykUni ! An EGGcellent opportunity to explore bold ideas in the welcoming team. Please RT!
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Many exciting talks to hear! Including our own @VolodymyrPorokh @Science_MEDMUNI
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Proud to contribute to this paper analysing lipid content of mouse and human oocytes.🥳 Big thanks goes to Reprofit International for recruiting sample donors for this project and long-standing academic-clinical research partnership💪@Science_MEDMUNI @Reprofit1
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See the thread of @VolodymyrPorokh for a short overview of the paper. https://t.co/42BqaGqTw7
nature.com
Nature Communications - The first zygotic cell division is more error-prone in humans than in other species, though it is not clear why these errors occur or how embryos recover. Here they show...
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The time-lapse records of preimplantation development obtained during fertility treatment are a real asset for basic scientists seeking to understand the cellular processes happening at the being of our lives. 👨🔬 🔬
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Our study investigating zygotic cleavage geometry using time-lapse data from IVF embryos has been published in Nature Communications! 💥 🤩 Many thanks to our clinical collaborators from Reprofit International. This work is an excellent example of academic-clinical partnership.
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Biggest reproductive conference of the year is over #ESHRE2023 Forefront science, networking, exchanging experience and sharing ideas. Meeting old and new friends🤩. Proud to present our work made in collaboration with Reprofit International and FutureLife consortium!
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Did you know that human and porcine #oocytes cluster their chromosomes before they assemble a spindle? Our latest study in @NatureCellBio reveals the mechanism and function of this unusual stage of #meiosis. https://t.co/KKQbYfjCoA (1/8)
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Outstanding effort and a beautiful result of hard work, we were happy to contribute to this journey!
18 years of work and 24 people in the team - we discovered the fusion protein on human egg and named it MAIA after Greek goddess of motherhood.
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Kudos to our Ph.D. student for receiving prestigious fellowship to do collaborative project with our colleagues in UK. Well done!
I am excited to share, that I have been awarded Boehringer Ingelheim Ph.D. Fellowship to study meiotic to mitotic cell cycle transition and microtubule organization in non-rodent eggs and embryos. Can't wait to join forces with Professor Mary Herbert @CBCC_NCL, @UniofNewcastle
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Finalists of “Cellim Microscopy Picture Contest 2021” are here! Vote for your favorite image and help us to select the winner of GoPro HERO10 camera offered by our sponsor Carl Zeiss spol. s r.o.! Pictures below: #fluorescence #microscopy #imaging #Ceitec #Brno #Zeiss
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LF MU #medmuni podala loni z @muni_cz nejvíce projektů @TACR_cz GAMA Proof of Concept. V 1. výzvě byly podpořeny projekty @KoledovaZuzana a Jana Balvana, ve 2. pak projekt @holubcova_lab. Účelem podpory je komercializace výsledků #VaV @MUNI_Science
https://t.co/puOl3BXVv3
med.muni.cz
V roce 2021 byla LF MU jednoznačně fakultou s největším počtem návrhů projektů podaných do vyhlášených výzev celouniverzitního projektu s názvem „Posílení systému komercializace výsledků VaV na...
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This project would not be possible without the immense support from @MUNI_Science and our collaborators both clinical @Reprofit1 and industrial @tescan_micro. Thank you all!
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Omne vivum ex ovo. Unprecedented view of our favorite cell! High-Resolution 3D Reconstruction of Human Oocytes Using Focused Ion Beam Scanning Electron Microscopy - is out now!
frontiersin.org
The egg plays a pivotal role in the reproduction of our species. Nevertheless, its fundamental biology remains elusive. Transmission electron microscopy is t...
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“Nature doesn’t understand disciplines. You can’t align biology to your skill sets; you have to ask questions and fearlessly develop the skill sets to answer them.” Thanks to @OtgerCampas for meeting with us! #embryo21 @MBLScience @lsprahl @biomathevan @BailonRaisa @manonvalet0
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The core member of our lab has just completed his studies at the Faculty of Medicine, Masaryk University. Congrats Volodymyr Porokh MD.! Next stage: PhD degree🤩
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A blastoid without trophectoderm is not a blastoid. I urge for more critical evaluation of embryo models! These models will undoubtably be extremely useful but we need to ensure that they properly model the intended human embryonic development.
biorxiv.org
Two recent papers in Nature show that human blastocyst-like structures (or blastoids) can be generated from human pluripotent stem cells[1][1] or through reprogramming of fibroblasts[2][2], respect...
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Bridging the gap between science and clinics. We report how application of unconventional IVF methods can make a difference for difficult-to-treat patients..
link.springer.com
Journal of Assisted Reproduction and Genetics - The most common reason for in vitro fertilization (IVF) cycle cancelation is a lack of quality gametes available for intracytoplasmic sperm injection...
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