Human Migraine Research Unit
@hmru_cph
Followers
2K
Following
2K
Media
469
Statuses
1K
We tweet about our migraine research, outreach, & achievements 🧠💡🏅📜🎓 A part of Danish Headache Center, Rigshospitalet, Denmark. Head of Lab: @MessoudAshina
Copenhagen, Denmark
Joined January 2016
RT @bidmcheadache: New study: IV infusion of substance P induced headache and arterial dilation in healthy adults. 71% reported #headache v….
journals.sagepub.com
Objective To determine whether intravenous infusion of substance P elicits headache and arterial dilation in healthy adults. Methods In a double-blind, placebo...
0
11
0
RT @TimothyPJenkins: 🚨 Big news! We’ve received an @novonordiskfond Tandem Grant for #MIGRAINE — designing AI-powered GPCR-targeting biolog….
0
3
0
RT @TimothyPJenkins: 🚨 We’re hiring a PhD student! 🚨. Join us at @DTUbioengineer + collaborators @MessoudAshina & @h_ashina + @esperdet to….
0
3
0
RT @lundbeckfonden: Congratulations to the LF Fellows 2025! .We are proud to announce that seven outstanding scientists have been awarded t….
0
4
0
🚨 New publication alert! 🧠.Our study just out in @braincomms identifies clinical predictors of response to erenumab for migraine prevention. Chronic migraine, daily headache & past med failures = lower odds of benefit. Toward precision medicine! 🔍.👉
academic.oup.com
Karlsson et al. report that in 570 patients with migraine from a tertiary headache centre, chronic migraine, daily headache and multiple prior preventive d
0
3
6
RT @JCephalalgia: A recent review on occipital neuralgia (ON), a severe and paroxysmal pain condition affecting the occipital nerves, analy….
0
6
0
🔬 New study finds signs of cortical inflammation in migraine using quantitative MRI! 📊 Higher T2 values in the occipital cortex suggest edema or immune activation in those with migraine aura. 🧠💥.Read more here:
0
6
13
RT @MessoudAshina: 🧠✨ Exploring the mysteries of migraine aura! Our latest fMRI study reveals how CSD alters CBF during spontaneous attacks….
journals.sagepub.com
Cortical spreading depression (CSD) is associated with pronounced alterations in cerebral blood flow. These alterations can be captured using high-field functio...
0
11
0
RT @MessoudAshina: 🚨News! I've been awarded a "Center of Excellence" grant by the Danish National Research Foundation. We're creating the C….
dg.dk
The board of the Danish National Research Foundation has decided to support the establishment of 13 new DNRF Centers of Excellence.
0
9
0
RT @bmj_latest: Some triptans are a more effective treatment for acute migraines than newer, more expensive drugs, finds an analysis of the….
0
82
0
RT @MessoudAshina: Thursday News 🗞️ Excited to announce our latest paper in @bmj_latest: a network meta-analysis comparing 17 acute #migrai….
bmj.com
Objective To compare all licensed drug interventions as oral monotherapy for the acute treatment of migraine episodes in adults. Design Systematic review and network meta-analysis. Data sources...
0
17
0
RT @NatRevNeurol: New online! Pituitary adenylate cyclase-activating polypeptide signalling as a therapeutic target in migraine https://t.c….
0
5
0
RT @SaitAshina: Migraine affects over one billion people worldwide, and new research highlights the role of PACAP in migraine pathogenesis.….
nature.com
Nature Reviews Neurology - Pituitary adenylate cyclase-activating polypeptide signalling has been linked to migraine pathogenesis. In this Review, Ashina and co-workers explore the molecular and...
0
6
0
RT @MessoudAshina: 🧠The signaling molecule PACAP plays a key role in triggering migraine attacks. Discover how PACAP could reshape migraine….
nature.com
Nature Reviews Neurology - Pituitary adenylate cyclase-activating polypeptide signalling has been linked to migraine pathogenesis. In this Review, Ashina and co-workers explore the molecular and...
0
24
0
Exciting news! In 2009, our lab was the first to show that the signaling molecule #PACAP can trigger #migraine attacks 🧠.Now, a phase 2 trial confirms that blocking PACAP can prevent them! A big step forward in migraine #research 🌟.Read more:
nejm.org
Targeting pituitary adenylate cyclase–activating polypeptide (PACAP) is a new avenue for treating migraine. The efficacy and safety of intravenous Lu AG09222, a humanized monoclonal antibody direct...
🚨 New hope for people with migraine! A Phase 2 study shows that a monoclonal antibody against PACAP reduces migraine days. 🌟@Rigshospitalet.@ihs_official @lundbeckfonden @hmru_cph @EHF_Official
1
3
21
🔬 New research paper finds hypersensitivity to BKCa channel opening in people with post-traumatic headache🧠.Targeting BKCa channels might open new avenues for drug discovery 💊@h_ashina @HaidarAlKhazal2 @BasitAliChaudh4 .Read more here:
thejournalofheadacheandpain.biomedcentral.com
Background Large conductance calcium-activated potassium (BKCa) channels have been implicated in the neurobiological underpinnings of migraine. Considering the clinical similarities between migraine...
0
5
10
Saturday news 🗞️ New study in @JCephalalgia reveals migraine attack induction via cGMP-dependent signaling can occur even during #CGRP receptor blockade using #erenumab🧠.Read more: @Raffaelli_B @MessoudAshina @h_ashina.
journals.sagepub.com
Background The cAMP and cGMP pathways are implicated in the initiation of migraine attacks, but their interactions remain unclear. Calcitonin gene-related pepti...
0
10
20
RT @PAINthejournal: .@HaidarAlKhazal2 et al. find that opening of KATP channels initiates cluster headache attacks during active phases, su….
journals.lww.com
urrent, severe headache episodes, succeeded by intervals of remission where no symptoms are present. In our study, we enrolled 41 participants: 10 with episodic cluster headaches during a bout, 15 in...
0
3
0
RT @PAINthejournal: Now in #PAIN: “Induction of cluster headache after opening of adenosine triphosphate-sensitive potassium channels: a ra….
journals.lww.com
urrent, severe headache episodes, succeeded by intervals of remission where no symptoms are present. In our study, we enrolled 41 participants: 10 with episodic cluster headaches during a bout, 15 in...
0
5
0