Ha X. Dang
@haxdang
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Bioinformatics, computational biology, cancer genomics
Washington University School of Medicine in St Louis
Joined September 2017
New review on lncRNAs in cancer metastasis, with special emphasis on current controversies and limitations of the field in general. @haxdang @chrismaher_lab @felixfengmd @danlimlab
nature.com
Nature Reviews Cancer - This Review discusses how long noncoding RNAs influence metastasis by functioning in discrete pro-metastatic steps including the epithelial–mesenchymal transition,...
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If we learn the lessons of COVID-19, we can approach climate change more informed about the consequences of inaction, and more prepared to save lives and prevent the worst possible outcome.
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Our work on clonal evolution of metastatic colorectal cancer, from primary to metastasis and patient-derived xenografts (PDXs). Very complex heterogeneity and evolution with clinical implication. Published in Science Advances.
Excited to share our @ScienceAdvances study on the clonal evolution of metastatic #colorectal #cancer in collaboration with Ryan Fields Second paper this week for @haxdang, a talented instructor in @ChrisMaher_Lab who led this massive analytical effort! https://t.co/iITgpnucRr
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Our paper is published in JCO Precision Oncology, showing preliminary data on the potential of monitoring the non-coding AR enhancer in cell-free DNA to predict patient response to AR-directed therapies.
First publication from our collaborative research with @aadel_chaudhuri and @RPachynski labs at @WUSTLmed
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Our study on #lncRNAs in metastatic #colon #cancer in collaboration with Ryan Fields' lab just came out in @NatureComms. https://t.co/knK2OPw0x1
@ACS_Research @SitemanCenter
nature.com
Nature Communications - The role of long non-coding RNAs (lncRNAs) in metastatic colorectal cancer (mCRC) and treatment resistance is unclear. Here, the authors use transcriptome sequencing of...
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Great to see this pooling approach for COVID-19 testing! New preprint shows an 8-fold increase in throughput. Each sample is part of multiple pools, using a combinatorial pooling strategy All 5 carriers in this pilot were correctly identified https://t.co/oceVVizOl8
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Our publication in @HeliyonJournal: Low expression of lncRNA LCAL62/LINC00261 is associated with poor survival in lung adenocarcinoma (881 patients, 6 cohorts, 3 platforms: RNA-Seq, microarray, and nanoString). https://t.co/j2J32tYFzI
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I did a deep dive into the COVID literature scanning 1300+ PubMed articles. I put together what I think is a core group of papers for clinicians and medical educators. You can access the library here: https://t.co/0JhP7AkmWY Pls send me your feedback! #FOAMed
#COVID19
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We’re excited to share that @Meta, a free research discovery tool, is now available. Meta provides a faster way to understand, organize, and explore science through personalized feeds. Researchers can now sign up for a free account https://t.co/sI1h7Xjxgy
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The 1-hour workday, ie. wake up early and spend the first hour of the day doing the "real" work.
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We are looking to fill some bioinformatics staff positions. Join a team working on a variety of projects in the areas of cancer, genomics, immunotherapy, precision medicine, ... https://t.co/GNdSVgznQ7 to learn more about the group. Contact myself and/or @obigriffith for details.
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Let's go Hokies!
HISTORIC DAY: Amazon has chosen Virginia as the #AmazonHQ2 destination, thanks to plans for a revolutionary, #VirginiaTech graduate campus in Alexandria, VA. 👏 👉 https://t.co/Pu33Cdxb8R
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First version of our new #PrecisionMedicine #Bioinformatics workshop now online. This tutorial series walks users through the hypothetical use case of processing a patient (cell line) exome/genome/transcriptome in preparation for clinical interpretation. https://t.co/SI8aQIMdHh
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In Canada we’ve had 15 mass shootings Since 1885. We have very tough gun regulations. In the US One mass shooting per day. Maybe I’m bias b/c I’m Canadian but isn’t it worth sacrificing a few guns to save thousands of children. Who will otherwise be killed, each day.
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For circulating tumor DNA to track #cancer, the fragments don't form randomly, there's a "preferred end signature," and that has implications for making the test more efficient https://t.co/lhkrGj9YNx
@PNASNews
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Investigators may soon be able to compare DNA crime-scene evidence to genetic profiles of nearly all Americans of European decent, but it raises urgent privacy issues.
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