Tomorrow at noon join Dr. Daniel Durocher, for "Understanding mitotic DNA damage tolerance by CIP2A." Please contact crina@ualberta.ca for the Zoom link.

On Wednesday, February 1, 2023, join Dr. Daniel Durocher, for "Understanding mitotic DNA damage tolerance by CIP2A." Please contact crina@ualberta.ca for your Zoom link. #CancerResearch #UAlberta

CIP2A Causes Tau/APP Phosphorylation, Synaptopathy, & Memory Deficits in #Alzheimersdisease @CellReports https://t.co/J3rfXYdqxj

Autoantibody response to a novel tumor-associated antigen p90/CIP2A in breast cancer immunodiagnosis https://t.co/SAaxeGp8Oj

The next Health Science Research Centre Seminar will be with Dr Claire Lucas on ‘The remaining questions for curing chronic myeloid leukaemia - the role of CIP2A and BCL-XL’. 1pm Friday 1 March in room 1014 #Whitelands

CIP2A is a prime synthetic-lethal target for BRCA-mutated cancers https://t.co/tVbuobHDh9 #immunobot

Khanna et al show that interrupting #CIP2A in #glioblastoma induces #CellSenescence and retards #TumorGrowth #inVitro and #inVivo suggesting CIP2A as an #anticancer #DrugTarget. https://t.co/SDvYDistjZ

Fascinating talk by Prof. Jukka @westermarcklab at @TampereUniMET #cancer tumorsuppressor #PP2A inhibitor-of-inhibitor #CIP2A

CIP2A- and SETBP1-mediated PP2A inhibition reveals AKT S473 phosphorylation to be a new biomarker in #AML https://t.co/FlDGWxvgcs

Hello I am Dr Claire Lucas I am a Haematology lecturer @UoCMedSchool @uochester and I actively research biomarkers which can predict clinical outcome for patients with #CML #leukaemia #CIP2A #ThisWomanDoes #WomenInScience #InternationalWomenScienceDay

Chronic Cigarette Smoke Exposure Subdues PP2A Activity by Enhancing Expression of the Oncogene CIP2A https://t.co/0vzbzr5xlU

⭐️ONLINE NOW @NatureCancer: "The CIP2A–TOPBP1 axis safeguards chromosome stability and is a synthetic lethal target for #BRCA-mutated cancer", a fantastic paper by @durocher1 &Co Don't miss it! 👇👇 https://t.co/mAE9G3oTY4 https://t.co/g4D6odZAvE

Protein #phosphatase 2A inhibitor oncoprotein CIP2A is located at the cilia transition zone, promotes the disassembly of primary #cilia and inhibits glycolytic #metabolism. --> https://t.co/espzrDR3Pj

Signaling #micropeptide CIP2A‐BP encoded by #lncRNA LINC00665 inhibits triple‐negative breast cancer progression by binding CIP2A oncogene and suppressing PI3K/AKT signaling -> Yifeng Zhou and colleagues at https://t.co/TJPOm6T9Kz

Today's ECR Seminar speaker is Dr Rahul Srivastava from Signal Transduction Lab @QIMRBerghofer He will be presenting his research that investigated the expression of CIP2A as a biomarker for PP2A inhibitor therapy in the treatment of Triple Negative #BreastCancer

Researchers showed that SP1-induced lncRNA DPPA2 upstream binding RNA promotes #stemness and #oxaliplatin resistance of #hepatocellular carcinoma via E2F1-CIP2A feedback. 🔄 Learn more 👉 https://t.co/l2JZ57oeZi

CIP2A and TOPBP1: Molecular lassos that herd pulverized micronuclear chromosomes

👩‍🔬 👨‍🔬 @UniTurku scientists have announced the discovery of a novel CIP2A variant, called NOCIVA, with clinical relevance in predicting tumor kinase inhibitor resistance in myeloid #leukemias. https://t.co/nLn5qM1R7J

癌の染色体破砕の際に複雑な遺伝子再編成が起こるが、その背景に切断された染色体断片がCIP2AとTOPBP1によっ��凝集することで飛び散らずに片方の娘細胞に遺伝することを見出した論文2報の紹介記事。どちらも今週のNature。 https://t.co/tQO7JD8R4D

Check out this nice work from the @durocher1 lab! As a reminder we have recently published our webserver https://t.co/m3nWDBv4aw where you can explore such relationships. e.g. CIP2A (KIAA1524) is significantly more essential in BRCA1/2 mutant breast cancer cell lines.