Check out the new biorxiv from graduate student Dan in our lab. He has created a new method (TIP-seq) that combines all of the best aspects of various protein-DNA binding assays to achieve some of the highest resolution data available at the single-cell level.
High throughput genome-wide single cell protein:DNA binding site mapping by targeted insertion of promoters (TIP-seq) [Daniel Bartlett, Vishnu Dileep, Steve Henikoff, David Gilbert] https://t.co/2nnwWoV1Rv ✅~10-fold more unique reads per single cell vs state-of-the-art methods
2
24
137
