Gianni Castiglione
@giannicast
Followers
125
Following
177
Media
3
Statuses
40
Vanderbilt Asst. Prof, Biological Sciences, Ophthalmology & Visual Sciences
Nashville, TN
Joined November 2009
Our newest paper is out in Science! This riddle took 5 years to solve. Genome annotation and AI missed it. Manual inspection and serendipity still have advantages for cracking nature's secrets! With @ScienceMagazine @EvolutionVU @RokasLab . | Science
0
3
11
RT @VICB_Vanderbilt: Big news from Vanderbilt! 🎉 Dr. Gianni Castalione’s latest paper in Science explores groundbreaking findings, and VICB….
0
1
0
RT @EvolutionVU: 🏇 Horses evolved a viral trick to outrun damage. The @giannicast Lab found a rare mutation that supercharges muscle energy….
0
2
0
Had a fantastic visit as the seminar speaker @yale_eeb ! Really stimulating conversations with such down to earth and creative people @Jenn_Coughlan @big_data_kane @TJNear thanks for the invite!
2
1
9
Excited to have our new paper highlighted AND on the cover in MBE!.
Excited to share MBE's first Highlight! Learn how Antarctic icefishes have adapted to see under the ice -- Looking through the Ice: Cold-Adapted Vision in Antarctic Icefish @giannicast @EvolutionVU @opsinlab @franceshauser @alexvn @UofTCellSysBiol
0
0
1
Our paper is out! w @HopkinsMedicine We explore how certain ACE2 mutations granting natural resistance to #SARSCoV2 infection will likely never evolve in humans (but maybe in dogs!).
Doomed by our physiology? @giannicast &co argue that, because of epistasis acting on #ACE2, ancient events in mammalian #cardiovascular evolution determined the host range of #SARSCoV2 millions of years before the current pandemic #PLOSBiology
0
1
0
Birding in Baltimore: Avian Antioxidant Innovations Predate Modern Medicine by 65 Million Years #behindthepaper.
0
1
2
RT @NatureComms: Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds:.htt….
0
7
0
We found that #Birds have supercharged antioxidants! They lost the master off-switch controlling antioxidant gene expression. This is a major clinical target, which could explain why birds have such long lifespans. Thanks to @LightsOutBalt @NatureComms.
1
6
19
Our team at @HopkinsMedicine found that human eyes are susceptible to SARS-Cov-2.
ACE2 and TMPRSS2 are expressed on the human ocular surface, suggesting susceptibility to SARS-CoV-2 infection #bioRxiv.
1
2
3
New eLife paper with @opsinlab "Functional trade-offs and environmental variation shaped ancient trajectories in the evolution of dim-light vision"
1
7
10
RT @SynBioCanada: We're delighted to announce that SynBio Canada is live! Read the latest #synbio news from Canada and abroad, and join the….
0
19
0
Check out our new paper with @opsinlab demonstrating molecular convergence in the visual system at high altitudes!
2
14
17
RT @uoftalumni: 🔬 The visionary research being done by @opsinlab provides an interesting glimpse at evolution in action. .
0
7
0