
Engle Lab
@EngleLab
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catalysis, reaction discovery, and samoyed sled racing @scrippsresearch. views our own.
La Jolla, San Diego
Joined September 2015
š„ My graduate-level #Organometallics course is now live on @YouTube! #chemtwitter . Designed for PhD chemists, this series covers history, mechanisms, catalysis, ligand design & more. Offered once every 2 yearsācheck it out anytime! . šŗ
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RT @JDerosaChem: Fantastic visit at @UniofNottingham School of Chemistry today sharing some of our recent work in @derosalab using voltageā¦.
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One week to go! 2025 OM Bootcamp @scrippsresearch kicks off on Aug 4th, 8 am PT. Welcoming participants in-person or over zoom, synchronous or asynchronous, low-spin or high-spin. Registerš.
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RT @mx_million: This is how you enable uptake of a new method! Hats off to the Knight Chemicals team for making a hydrazides coupling startā¦.
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RT @angierangeles: Autograph signings ā¦@ACSorganicā© 2025 National Organic Chemistry Symposium! ā¦ā¦Future scientists with some of our plenaryā¦.
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RT @scrippsresearch: Prof. Jin-Quan Yu (@YulabJin) will receive the 5th Akira Suzuki Award for his research on CāH bond activation, which mā¦.
magazine.scripps.edu
Jin-Quan Yu, the Bristol Myers Squibb Endowed Chair in Chemistry and the Frank and Bertha Hupp Professor in Chemistry at Scripps Research, has been selected as the recipient of the 5th Akira Suzuki...
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The age old question: what's happening in the flask? š§Ŗš¤. Join G2 student @avrlisboa for a ā²ļø brief video primer on ReactIR as a tool to answer this question and free up your time!.
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atropisomers? positional isomers? both?. We present beautiful and curious class of molecules today in @ChemRxiv. š§šŖ. @ASimlandy @0iTurki @pengliu_group
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Unexpected reactivity ā simple access to dihydro-1-benzazepines! Now out in TL š . Part of a special issue celebrating @SongLinLab's Tetrahedron Young Investigator Award š
Big thanks to undergrad Letian + the whole team š.
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Great to see @derosalab out in full force! This team is crushing it!.
Best way to cap off an amazing #ACSSpring2025 meeting. Always feels like home @scrippsresearch - now with an extended academic family tree!
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The mechanism, termed asynchronous amine-assisted metalation/deprotonation is distinct from the various forms and flavors of CMD that we are accustomed to. In fact, canonical carboxylate bases shut down the reaction! @YilinCao_chem & @cagan_da led the charge on pinning it down!.
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Alkyl hydrazides are proving to be game-changers across many transformations, including Ni-catalyzed C-H activation! . For fellow C-H activation nerds š¤, one point not to miss: the amine base used for radical generation plays a critical role in the CāH activation step.
Ni-Catalyzed CāH Alkylation of (hetero)arenes: Super simple, broad scope, enabled by sulfonylhydrazides! Appearing today in @ChemRxiv (. An awesome joint venture with the amazing @EngleLab. Quick Summary:. A new method for facile CāH alkylation of a
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RT @W0TangClan: In my latest preprint with @morandilab we take a new approach to C-H functionalization by trading C-H and C-X bonds betweeā¦.
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>3 years in the making, we are excited to debut @sunjuntao1's discovery of copper(II) as a potent Ļ-Lewis acid catalyst for redox-neutral, regiodivergent OH and NH additions to unactivated alkynes. Great teaming up w/ @pengliu_group. @ChemRxiv
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RT @pengliu_group: Excited to introduce our website and preprint about HArD, a database of heteroaryl descriptors. If you ever wondered "whā¦.
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We've been drawn to selective activation of C(alkenyl)āH bonds for a long time. In a new @ACSCatalysis paper, @sunjuntao1 & team turned attention to an interesting situation where functionalizing enamine-type azaheterocycles creates a chiral CāN axis.
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As an organic chemist, sometimes your most important contribution is attempting to destroy beautiful complexes from collaborators by exposing them to air, and failing. The final version of this fun study on bench-stable CuH is now online in @angew_chem.
onlinelibrary.wiley.com
A bottom-up approach leveraging preexisting m-center-n-electron (mc-ne) bonds enables the synthesis of a highly stable cyclic(alkyl)amino carbene (CAAC) copper-hydride nanocluster, [(CAAC)6Cu14H12]...
A bench-stable catalytic CuH cluster inspired by Stryker's reagent. w/ @Rodolphe_Jazzar and P.-A. Payard labs
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RT @derosalab: With the Gutierrez group @UCLA , we report a unique mode of electrocatalytic semi-hydrogenation to generate Z-alkenes usingā¦.
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