
Robert Cincotta
@drrobcincotta
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Maternal-Fetal medicine specialist & PhD candidate in AI for twin pregnancies. Husband, dad, techno optimist, golfer, AFL fan. Thriving at full speed.
Brisbane, Queensland
Joined April 2022
Another wonderful example of gene therapy working. Hope many more coming soon.
Before the injection of GC301 gene therapy, the 3-month-old patient had mouth breathing, was unable to lift the head, and had low limb-muscle tone. One month after the injection, the 4-month-old patient was able to lift the head to 90 degrees in the prone position and lift the
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🚨 This is a cutting-edge application of AI in medicine. A new AJOG study uses unsupervised machine learning to identify distinct twin growth patterns—transforming how we predict risk in twin pregnancies. 🧠👶 New research by Prasad et al in AJOG uses machine learning to uncover
Longitudinal twin growth discordance patterns and adverse perinatal outcomes - Incidence of adverse outcomes across inter-twin discordance trajectories https://t.co/2onuxeMPzV
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Vaginal progesterone reduces the risk of preterm birth and adverse per...
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Updated IPD Meta-Analysis (AJOG, 2025) Vaginal progesterone reduces preterm birth in singleton pregnancies with a midtrimester short cervix (≤25 mm): 🔹 37% ↓ in preterm birth <33 weeks (RR 0.63) 🔹 Significant ↓ in PTB <36, <35, <34, <32 weeks 🔹 ↓ Respiratory Distress
Vaginal progesterone reduces the risk of PTB and adverse perinatal outcomes in singleton gestations with a midtrimester sonographic short cervix (≤25 mm): an updated individual patient data meta-analysis - Effect of vaginal progesterone on PTB <33 weeks https://t.co/2XwPRerVeh
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💊 Aspirin to prevent preeclampsia in twin pregnancies: New insights! A study of 1,907 twin pregnancies across 3 European centres compared no aspirin, 80–100 mg, and 160 mg/day doses. ✅160 mg aspirin: Reduced preeclampsia risk by 37% (HR 0.63) Lowered hypertensive disorders by
Comparison of two aspirin doses for the prophylaxis of pre-eclampsia in twin pregnancy: a multicenter retrospective study with propensity score matching - Kaplan-Meier plots according to aspirin dose after adjustment https://t.co/AwS2itn7ae
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🚀 AI just turned a year-long academic slog into a 2-day sprint! I read a mind-blowing article about Otto-SR, an agentic AI built on LLMs, that’s revolutionizing systematic reviews in medical research. Systematic reviews—where teams spend months sifting through mountains of
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Perinatal mortality and other severe adverse outcomes following planned birth at 39 weeks versus expectant management in low-risk women: a population based cohort study - eClinicalMedicine
thelancet.com
Planned birth at 39+0–39+6 weeks in low-risk women was associated with lower odds of perinatal mortality and other adverse outcomes. Reductions in odds of adverse outcome were greater following...
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🩺 New study alert: Plan birth at 39 weeks? Huge study of 472,520 low-risk women says YES! 👼 52% drop in perinatal deaths 🧠 46% less severe neurological issues 🩺 65% fewer non-neurological problems 🙌 Induction = fewer C-sections, less trauma 💊Induction of Labor = ↓
Birthing study reveals ‘safest time’ to have a baby https://t.co/TRWQGq99l7 via @australian The science is settled!
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Birthing study reveals ‘safest time’ to have a baby https://t.co/TRWQGq99l7 via @australian The science is settled!
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Impact of Aspirin on Timing of Birth in Pregnancies With Clinical Manifestations of Placental Dysfunction: Evidence From a Multicentre Randomised Clinical Trial - Papastefanou - BJOG: An International Journal of Obstetrics & Gynaecology - Wiley Online Library
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New BJOG study: Can aspirin delay birth in high-risk pregnancies? • 🩸 Low-dose aspirin (before 16 wks) prolongs gestation in women at high risk for preeclampsia (PE) and other placental dysfunctions (PD). • 📉 Risk of PD <32 wks reduced by 45% with aspirin. • ⏳ The earlier
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Fetal intracranial hemorrhagic complications following intrauterine transfusion for severe fetal parvovirus B19 infection - Hong - Ultrasound in Obstetrics & Gynecology - Wiley Online Library
obgyn.onlinelibrary.wiley.com
Click on the article title to read more.
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Thrilled to share our new letter in Ultrasound in Obstetrics & Gynecology on cerebellar hemorrhages in fetuses requiring intrauterine transfusion (IUT) for parvovirus B19 infection. 🩺 This rare condition can lead to severe fetal anemia, and our case series at Mater Centre for
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📚🤖Using AI as my reading buddy After 45 years of attempting to finish James Joyce’s Ulysses (a longer time than Odysseus took to get home and I even had a daughter finish it at Uni before I could!), I’ve found a new way forward: using AI as my personal literary guide. Family
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Prenatal cell-free DNA testing of women with pregnancy-associated cancer: a retrospective cross-sectional study - The Lancet Regional Health – Europe
thelancet.com
All genome-wide NIPT in women with pregnancy-associated haematological malignancies were malignancy suspicious. Women with a solid tumour showed a malignancy suspicious-NIPT in only a minority of...
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🩺 Did you know NIPT can spot cancer? NIPT is used to screen for fetal chromosomal disorders in early pregnancy—but sometimes it picks up maternal cancer as well. 📄 A new nationwide Dutch study of 65 women with pregnancy-associated cancer found: 🔍 24.6% had NIPT results
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Survival rates in pregnancies complicated by twin-to-twin transfusion syndrome undergoing laser therapy: a systematic review and meta-analysis - American Journal of Obstetrics & Gynecology MFM
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📊 New Insights on TTTS: Meta-Analysis Highlights A recent systematic review and meta-analysis (AJOG MFM, May 2025) dives into survival rates for TTTS pregnancies treated with laser therapy since 2010. Here’s what 26 studies, covering 5,030 monochorionic diamniotic (MCDA) twin
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