Mohamed Donia
@donia_lab
Followers
794
Following
10
Media
1
Statuses
57
Assistant Professor of Molecular Biology at Princeton University, studying the role of small molecules in complex microbiomes.
New Jersey, USA
Joined August 2016
Our first pre-print! Check it out:
Development of a Covalent Inhibitor of Gut Bacterial Bile Salt Hydrolases https://t.co/gqQZJVQdBp
#bioRxiv
1
7
13
Please RT: I'm looking for an awesome postdoc to come and help us define how exposure to environmental pollutants disrupts the gut microbiome's contribution to behavioral development. Learn more at https://t.co/jIW6fkeo8T or contact me with questions.
5
113
84
Check out @Melissa_Galey preprint, collaborative work w/ @JBurdetteLab funded by @UIC_CCTS & laid the ground work for our recent @RCSA1 grant with @JudithTTSu : https://t.co/5cTAtB9lzK This preprint shows MALDI-TOF #MassSpec is promising for following #OvarianCancer in vivo
biorxiv.org
Background Sampling a local microenvironment represents a potentially informative method for monitoring disease progression due to proximity between the sample and diseased tissue. Mass spectrometry...
0
4
9
Thanks, everyone. It is by the support of this extremely kind community that we survive day to day. There are so many people who helped us here, from ones who helped us get samples when we couldn’t travel, to others who allowed us to use their enabling equipment. 1 M thanks.
0
1
4
If you are interested in learning more about our recent study in marine sponges, please check out this piece by Dai Tianero, the amazing post doc who led this work: Cellular reservoirs of defensive symbionts in sponges https://t.co/yMczic6ry2
#behindthepaper
0
3
9
Sponges, the oldest living animals, dedicate one of the few types of specialized cells they harbor towards housing intracellular symbionts for the production of complex defense chemicals, which is pretty much all these symbionts do.
Tianero et al.: Marine sponges retain symbionts that produce the defense chemical renieramycin in specialized reservoirs (chemobacteriocytes): https://t.co/Qggf3VzAyc
9
28
97
I am asking this genuinely. What is the best use of Twitter for the scientific community: 1. learn about other work in your field, 2. publicize your own work, travel, paper, or grant, 3. voice your opinion about scientific or other issues, 4. share usually untold experiences?
3
1
5
Very grateful to have worked with an amazing team of scientists on this project throughout the last 3.5 years: 6 people from 6 countries! I am also very thankful to the continuous support of remarkable colleagues at @Princeton & mentors throughout the journey of a #YoungPI 6/6
1
0
7
We hope that our systematic screen will be a resource for the @US_FDA, a starting point for many follow-up investigations, and a motivation for including microbiome studies in future drug development. 5/6
1
0
4
As a Pharmacist and Medicinal Chemist by training, this is a stunning result, given that microbiome effects are almost completely overlooked in the typical drug development pipeline (despite more than 50 years of studies suggesting microbiome importance in drug metabolism). 4/6
1
0
2
Using personalized, optimized, and well characterized microbial communities, an analytical chemistry platform, a drug library screen, and microbiome-dependent pharmacokinetics, we show that at least 13% of the drugs we administer orally can be transformed by the microbiome! 3/6
1
0
3
Ever wondered how hundreds of orally administered medications can interact with our gut microbiome? or how many drugs can the gut microbiome of a single human biochemically transform? We have developed a simple screen to answer these questions "MDM-Screen". 2/6
1
0
2
Here we go world, our first @donia_lab preprint and manuscript to hit the web: @biorxivpreprint @biorxiv_micrbio "Systematic mapping of drug metabolism by the human gut microbiome" https://t.co/nAY7Y6KxIl -- more details in this thread 1/6
5
29
62
New #RaininIBD website helps researchers connect & collaborate. Together, we can solve #InflammatoryBowelDisease. https://t.co/X0uXGrsH4w
0
3
1
Professor Michael Levine is one of 65 outstanding life scientists elected to @EMBOcomm: https://t.co/cy68vSNiKr
0
2
11
Our -80 yesterday! love how creative my students and post docs are, especially the last sentence! #LateInTheLab
0
0
4
This is the time for the private sector to step in and save our young brilliant scientists from totally giving up!
US science faces a political storm, and early-career researchers should prepare for a bumpy road in the Trump era https://t.co/TaXVomUeDy
0
2
0
Congrats to All! Natural Product labs depend on your great work.
I see that at the same day as antiSMASH4 ( https://t.co/hcGXoSnmDx), PRISM3 is also online ( https://t.co/YMAF1vpVPl). Congrats, @nmagarvey1 !
0
1
2