Daniel Turner
@dcturner93
Followers
1K
Following
10K
Media
28
Statuses
1K
First day as Assistant Professor at the University of Pavia. Grateful for this opportunity and excited (and nervous) for the journey ahead!👨🔬🤌
99
59
3K
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 It started from my frustration with the depressing effect that the current publishing system has
106
487
2K
Response of UBR-box E3 ubiquitin ligases and protein quality control pathways to perturbations in protein synthesis and skeletal muscle size | American Journal of Physiology-Cell Physiology | American Physiological Society
journals.physiology.org
The N-degron pathway contributes to proteolysis by targeting N-terminal residues of destabilized proteins via E3 ligases that contain a UBR-box domain. Emerging evidence suggests the UBR-box family...
0
0
4
Checkout the new paper from Leslie Baehr, @HughesDC_Muscle & Team, which also involved the CMR's @CraigAGoodman1 Response of UBR-box E3 ubiquitin ligases and protein quality control pathways to perturbations in protein synthesis and skeletal muscle size https://t.co/APhPfErAMa
journals.physiology.org
The N-degron pathway contributes to proteolysis by targeting N-terminal residues of destabilized proteins via E3 ligases that contain a UBR-box domain. Emerging evidence suggests the UBR-box family...
1
4
15
🚨Hiring a 2yr postdoc in the lab work on muscle biology, genomics & ALS. Expertise in the above advantageous, but work ethic, desire to learn/develop and being a good scientist/person more important. Some travel to CPH involved as well! https://t.co/88blHJGQXS
1
17
23
Happy to share our new preprint: Subcellular mRNA localization patterns across tissues resolved with spatial transcriptomics: https://t.co/ejJMnMaYQF We utilize VisiumHD to extract intra-cellular mRNA polarization patterns in epithelial tissues.
1
29
148
Unexpected effects of semaglutide on skeletal muscle mass and force-generating capacity in mice https://t.co/aDONffDnRg
cell.com
Loss of lean mass is a potential concern for semaglutide-induced weight loss. This study indicates that semaglutide has unexpected effects on skeletal muscle mass and strength in mice, demonstrating...
0
9
34
Morphological differences in myofibre size and shape: A comparative study of the soleus, gastrocnemius, triceps brachii and vastus lateralis in humans and mice https://t.co/MEZyNIe7VX
onlinelibrary.wiley.com
Myofibre size and shape were investigated in functionally distinct muscles of humans and mice using ATPase histochemistry and immunofluorescence. In both species, soleus myofibres were found to be...
2
19
95
Finally out! The first of many on the Trajectories of Aging. https://t.co/8KAVCW0Jar Great team work @HIPE_lab @PorcelliSimone @MVFranchi @re_re84 @marconabacino @c_brusco @MarcoCarbonaro2 @MassimilianoAnsaldo @CaterinaAmendola
agsjournals.onlinelibrary.wiley.com
Objectives To examine the structural, metabolic, and functional trajectories of neuromuscular decline in aging and identify key mechanisms and early biomarkers to guide interventions preserving...
0
6
24
Liverpool striker Diogo Jota and his brother have both passed away due to traffic accident, reports Marca. Deepest condolences, support, and thoughts are with those involved, his family and loved ones. May his soul rest in peace. 🤍🕊️
21K
75K
626K
Is taurine an aging biomarker? Apparently not. Do taurine levels correlate with any sort of health status? Apparently not. Were prior high-profile claims as to the benefits of taurine reproducible? Apparently they were not. https://t.co/R0AJBnhyOM
science.org
Low circulating taurine concentrations have been proposed as a driver of the aging process. We found that circulating taurine concentrations increased or remained unchanged with age in three geogra...
8
31
100
🚨Session 5 of the @ScienceinSport Webinar Series Exploration of the latest research and emerging perspectives on protein requirements specific to endurance exercise and athletes. 📆 Mon 9th June 🌍 Global times below 🎙️ Prof. Daniel Moore Register: https://t.co/nVf4xgbbBP
0
2
5
Amazing to see this collaboration paper in @CellPress @CellReports Molecular landscape of sex- and modality-specific exercise adaptation in human skeletal muscle through large-scale multi-omics integration! Led by @nir_eynon & @MacsueJ
https://t.co/dStU9gAI3J
0
8
25
Does #antioxidant supplementation influence the outcomes of #SIT #training? #skeletalmuscle fans, we might have some information for you. #proteomics leads the way! https://t.co/KLOeUOVuaH Kudos to the great Håkan Westerblad and to the whole amazing team.
physoc.onlinelibrary.wiley.com
Abstract figure legend Sprint interval training (SIT) is a popular time-efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all-out cycling sprints) over...
1
8
29
Fancy doing a PhD or know someone that does? If so, please apply or share. Deadline 18th June for mid/late Sept start https://t.co/rYVHTxnzZU
findaphd.com
PhD Project - Identifying regulators of the GUT-muscle axis to improve muscle resilience across the lifecourse “GUTS” at University of Southampton, listed on FindAPhD.com
0
23
19
When is a change in mitochondrial bioenergetics reflective of 'mitochondrial dysfunction' vs 'intentional reprogramming'? Here we present traditional vs alternative interpretations of mitochondrial responses to muscle disuse. https://t.co/mvtMxAGnp3
4
44
220
NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging https://t.co/AAYaL8FZKf
cell.com
NAD depletion in skeletal muscle does not impair tissue integrity and function or accelerate aging, as shown in a mouse model with an 85% decrease in muscle NAD+ levels. Muscle structure, metabolism,...
0
9
34
Integrated single‐cell functional‐proteomic profiling reveals a shift in myofibre specificity in human nemaline myopathy: A proof‐of‐principle study https://t.co/uoCxfgkhYZ
physoc.onlinelibrary.wiley.com
Abstract figure legend SMPFO uniquely develops data relating to the biophysical state of the sarcomeric protein, alongside global proteome profiling, on a single myofibre basis. Using this approach...
0
7
29