David Bjånes
@davidbjanes
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post-doc @caltech, engineer, motorcycles, captain of @serenitysailboat, alpinist
Los Angeles, CA
Joined December 2008
980 Electrodes, 956-2246 days implanted, 11 Utah arrays, three human participants, and 6000 SEM images. Comparing damage of explanted electrodes with in-vivo performance (stimulation + recording) to understand longevity of brain computer interfaces. #BCI
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RT @ActaBio: Professor Richard Andersen: Quantifying physical degradation alongside recording & stimulation performance of 980 intracortica….
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Check out our new review of current state of the art of sensory BCI!.
New paper on @SfNJournals: "Clinical Applications and Future Translation of #Somatosensory #Neuroprostheses" from @SfNtweets . @emily_graczyk @BriannaHutchison @davidbjanes DeannaGates @SRaspopovic @robert_gaunt1. @BionicsNeural @ClevelandFES @Corbionics
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6/6 Huge thanks to a large cast of collaborators at @JHUAPL, @UUtah, @UCLA, @USC and @Caltech. @MattFiferNeuro @BlackrockNeuro_ @sskellis Loren Rieth @CaltechN and many others!.
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5/6 Most arrays had spatially correlated electrode damage, recording performance (SNR) and electrophysiological measures (impedance, noise) using Moran’s I. This suggests underlying biological factors for our results, rather than stochastic manufacturing variability.
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4/6 Platinum (Pt) vs. Sputtered Iridium Oxide Film (SIROF): same participant (956 days), 2x single neurons on SIROF. Impedance (Z) correlated with damage (✅SIROF, ❌Pt.), predicted SNR and if an electrode could evoke an intra-cortical micro-stimulation (ICMS) sensation.
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3/6 We hypothesize typical electrode degradation begins with cracking of tip or insulation (B-E). Biotic processes erode silicon, leaving fragile tip metal w/o support. Flaking or cracking (F-J) exposes more silicon, erosion of weak lattice nodes causes shank pieces to fall (K-L)
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2/6 Quantified five damage metrics: 1) tip metal, 2) insulation, 3) separation between metal/silicon, 4) tissue growth, 5) silicon shaft. We identified a new type of metal degradation ("pockmarked"), predominantly observed on SIROF electrodes; BUT stimulation ~∝ tip metal damage
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1/6 BCI devices enable communication and motor control for people with disabilities, by mapping recorded brain activity to control signals. Recording ability decreases with electrode damage, Utah arrays last ~5 yrs. By identifying common failure modes, next gen might last longer.
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Really excited to finally get this out! @sarah_wandelt.
.@sarah_wandelt et al. introduce a brain-machine interface that can translate intracortical neural activity during inner speech (no movement, no sound) into text in real time.
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Still under review, but some interesting data on disregulation of organ systems, innervated by the vagus nerve.
Dysfunction of the vagus nerve in #LongCovid: .a comprehensive structural and functional assessment supports a "central pathogenic role" .Multiple clinical trials of non-invasive vagus nerve stimulation are underway
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Haha what a fun meeting!.
@BciSociety 2023 meeting was a blast. There is *so* much cool stuff going on in this field that would have felt unthinkable attending my first meeting 10 years ago. Happy I get to share the journey with these weirdos. :)
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RT @SumnerLN: So excited to finally share this work on @biorxivpreprint demonstrating transcranial functional ultrasound brain imaging thr….
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RT @ZsofiaTorok8: I am excited to share my first-author pre-print in songbirds, where we explore mechanisms of brain circuit restoration at….
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One of our remarkable participants in the Andersen Lab. Not only is she passionate and dedicated, Nancy is an incredible artist!.
Do you know Nancy Smith? With a degree in psychology and an MA in family therapy, she is an artist, author, teacher and mother. After a car accident left her with a spinal cord injury, she also became a BCI Pioneer. Read her story: #Neurotech #BCI
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RT @317070: Did you know, that you can build a virtual machine inside ChatGPT? And that you can use this machine to create files, program a….
engraved.blog
Unless you have been living under a rock, you have heard of this new ChatGPT assistant made by OpenAI. Did you know, that you can run a whole virtual machine inside of ChatGPT?
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Glad to share my thoughts on the new @neuralink demonstrations. Collaboration between scientists and engineers benefits both. Science can discover new knowledge to better design new engineering tools to make awesome stuff. @elonmusk.
California-based brain-computer interface researchers comment on the @neuralink show and tell. Some hype, some engineering advances. Check it out at the @mercnews here:
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RT @WhitneySGriggs: Thrilled to share our latest work on @biorxivpreprint demonstrating the first real-time closed-loop ultrasonic brain-ma….
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RT @blekhman: Breakdown of PhD student cost on a grant: . tuition $45K.stipend $35K.fringe $10K.indirects $60K.--.total paid by NIH to univ….
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RT @NeuroCellPress: New issue -> Cover is by @kreldjarn for a study showing grasp & speech signals found in the cor….
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