cwiklik_lab
@cwiklik_lab
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Biological interfaces at nanoscale, cell membranes, tear film, lung surfactant, bio-nonbio interfaces of implants, drugs. At J. Heyrovsky Institute.
Prague, Czech Republic
Joined October 2017
Our latest study dives into how water vs. ethanol influences ibuprofen nanoparticle formation. From aggregation to dispersion, solvent choice matters. 🌊🍷 Smaller NPs mean better control in drug formulation and delivery. https://t.co/11HkvSgkxv
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#research #antimicrobials #medicinalchemistry LEGO-Lipophosphonoxin membrane activity is enhanced by presence of phosphatidylethanolamine but hindered by outer membrane (Rejman, Fišer, Mikušová) - @SciReports: https://t.co/eI7rFNRPKm
@IOCBPrague @science_charles @JHINST_Prague
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🧫Vitamin E acetate and some other substances in e-cigarette liquids deform and weaken the protective lipid layer inside the lungs. This was found by @cwiklik_lab at @JHINST_Prague in collaboration with the University of Helsinki. @SciReports 👉 https://t.co/SgVN40g0bk
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#NewArticle #OpenAccess Can calmodulin bind to lipids of the cytosolic leaflet of plasma membranes? | Open Biology
royalsocietypublishing.org
Abstract. Calmodulin (CaM) is a ubiquitous calcium-sensitive messenger in eukaryotic cells. It was previously shown that CaM possesses an affinity for dive
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Our newly published SciRep paper highlights the health risks posed by additives in e-cigarettes, including propylene glycol and vegetable glycerin, commonly used in e-liquid mixtures. @JHINST_Prague @IOCBPrague @helsinkiuni @InnoRenewCoE
https://t.co/0lrKy4I2rD
nature.com
Scientific Reports - Assessing vitamin E acetate as a proxy for E-cigarette additives in a realistic pulmonary surfactant model
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Thrilled to have visited the Materials and Surface Chemistry Group at Faculty of Chemistry at @JagiellonskiUni together with @DenysBiriukov Big thanks to everyone for making it so productive and fun 😀 @iedynak
https://t.co/InN49xGZdk
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Can calmodulin bind to lipids of the cytosolic leaflet of plasma membranes? Find out in recent #OpenBiology study from @scollo_federica and colleagues @BioPhysChemJHI @JHINST_Prague
https://t.co/F911mxrtie
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Kamila has just defended her PhD thesis 😀 Congratulations and good luck in the new group 👍
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https://t.co/dRZ2XhhjDL I am beyond excited to share that the we got an answer to the question: “Can calmodulin bind to lipids of the cytosolic leaflet of the plasma membrane?”. Please, check it out!
royalsocietypublishing.org
Abstract. Calmodulin (CaM) is a ubiquitous calcium-sensitive messenger in eukaryotic cells. It was previously shown that CaM possesses an affinity for dive
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A new preprint on lipid dynamics in MD simulations! Initially planned as a multidisciplinary work with @SChiantia, we eventually split it into 2 manuscripts: Computational part (out today): https://t.co/vVqZ4AwQDC Experimental part (also fairly fresh!):
biorxiv.org
Cellular membranes are composed of lipids typically organized in a double-leaflet structure. Interactions between these two leaflets – often referred to as interleaflet coupling – play a crucial role...
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Back from Prague! Attended the PhD defence of Man whom I advised at @IOCBPrague; watched Katarina @cwiklik_lab measure data for future proposals; gave a talk at @JHINST_Prague; met many old&new colleagues; and went for a long hop-scented run along Vltava, followed by some duck 🥰
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My new group at @Physics_TAU @TampereUni has an open postdoc position! Retweets and distribution by other means are highly appreciated☺️ https://t.co/naWRvZhzuE
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[Jobs and Events] Ph.D. position in Biomolecular chemistry and bioinformatics, Masaryk University, Brno, Czech Republic: https://t.co/5cKWE4pDsu
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Signed by over 120 experts, our letter highlighting the urgent need for a collaborative effort to establish a #FAIR database for #MolecularDynamics simulation data, is now on Arxiv. 📎 Read it here: https://t.co/VE3qMULPRX 📝Support our statement: https://t.co/7vp58TPy1A
#MDDB
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New #publication out! We were curious what happens with the lipid #membrane if #proteins are inside. As a model of membrane proteins we use transmembrane #peptides with neutral and positive charge. The #charges turn out to be crucial in the peptides influence on the lipids. 1/4
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A cover art for our paper dealing with the behavior of the lipid tails at the palmitoylated transmembrane domains. Surprisingly for us, the non polar tails increase water penetration into the membrane https://t.co/7USAStAZlN
@JHINST_Prague @IOCBPrague @JavanainenM
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Dr. Wojciech Pajerski, #InnoRenew CoE researcher, visited @JHINST_Prague. He explored @cwiklik_lab, which specializes in bio-interface research using various techniques, such as novel Brewster+fluorescence microscopy, revealing exciting opportunities for future partnerships.
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More good news today. I am so glad that our joint project with @DenysBiriukov from @CEITEC_Brno on implantable polymeric materials was funded by Czech Science Foundation #GACR. Hey, Gram-negative bacteria, beware! 😀
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We are glad to be part of the AMULET project. Working towards new biocompatible materials.
👏Congratulation! Project AMULET has received a financial support from Excellent Research Call https://t.co/wRu10vru59 The challenge is to develop advanced, so-called multiscale materials with a wide range of applications #amulet #nano #nanomaterial #grafen #2Dmaterial #senzor
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#research #MDsimulation Palmitoylation modifies transmembrane adaptor protein PAG for ordered lipid environment: A molecular dynamics simulation study (Cebecauer, Cwiklik @cwiklik_lab) - Biophysical Chemistry: https://t.co/f8YXGhVWkB
@JHINST_Prague @IOCBPrague @science_charles
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