Christian Santos-Medellín
@cmsantosm
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🇲🇽 • research scientist • plant microbiomes • soil virosphere • data viz
Joined February 2021
Our most recent paper is out @NatureEcoEvo! We characterized the temporal dynamics of viral, bacterial, and relic DNA via a highly replicated microcosm setup: 4 grassland soils, 7 time points, 144 viromes, 84 metagenomes, and 84 16S rRNA gene profiles. https://t.co/e9Uu0Xr4ir
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First step in a community project to provide a uniformly assembled, annotated and searchable set of bacterial genomes, our preprint on our initial release of 1.9 million genome assemblies+taxonomic estimates. (figure compares with previous 661k dataset) https://t.co/RLQiUBZJNk
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We updated our paper: Systematic Discovery of Antibacterial and Antifungal Bacterial Toxins https://t.co/RaUbC3iRla
biorxiv.org
Microbes employ toxins to kill competing microbes or eukaryotic host cells. Polymorphic toxins are proteins that encode C-terminal toxin domains. Here, we developed a computational approach to...
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This is *why* methods matter for #SoilHealth indicators: the 24 hr interval of the #HaneyTest represents an entirely different microbial community activity than at 72 or 96 hrs (as in the Cornell test).
Differences in the relative abundances of Actinobacteria (enriched in dry soils) and Proteobacteria (enriched in wetted soils) matched those of their predicted phages, indicating viral predation of dominant bacterial taxa.
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Soil viruses the minute the first seasonal rainfall hits the ground:
Despite vast compositional differences across soils, rewetting of dry soils consistently resulted in a bloom of viral diversity (up to a >30-fold increase in vOTU richness 24 h after wet-up!), followed by extreme turnover of viral populations.
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Thanks to @jemersonmicro and the rest of the team for all their support. Thanks also to @j_kosmopoulos and @KarthikGeomicro for this wonderful commentary:
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Rewetting also rapidly depleted relic DNA, which subsequently reaccumulated, indicating substantial new microbial mortality in the days after wet-up
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Differences in the relative abundances of Actinobacteria (enriched in dry soils) and Proteobacteria (enriched in wetted soils) matched those of their predicted phages, indicating viral predation of dominant bacterial taxa.
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Despite vast compositional differences across soils, rewetting of dry soils consistently resulted in a bloom of viral diversity (up to a >30-fold increase in vOTU richness 24 h after wet-up!), followed by extreme turnover of viral populations.
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New paper alert!🌋🌊🧬🦠 I'm so excited to share our paper "Viruses interact with hosts that span distantly related microbial domains in dense hydrothermal mats" 1/
nature.com
Nature Microbiology - Metagenomics and Hi-C proximity-ligation sequencing show that viruses in dense microbial communities can interact with multiple, distantly related microbial hosts.
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🚨Preprint alert! Excited to share our newest #preprint on #virus diversity and activity in high-altitude soils. A joint effort with @simroux_virus and @elbrodie’ Group 🙏. Check it out here:
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Happy to share a new preprint with @jemersonmicro. Viral communities with minimal compositional overlap display remarkably similar successional trends upon rewetting dry soils. https://t.co/xrun7NxwV7
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This is a great opportunity for any microbial ecologist looking for a postdoc. Exciting research topic, phenomenal advisor, and great colleagues.
Our lab at UC Davis is looking for a soil viral ecology postdoc, but we can't formally advertise it yet, due to [recent successful negotiations that will absolutely be accounted for]. Avail. now, open to waiting for right candidate. More hopefully soon!
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Viruses are tiny, but play a big ecological role. Researchers @ucdavis, @ucmerced, @UCBerkeley & @Livermore_Lab monitored areas of grasslands, with some only getting 50% of average rainfall. They found the viruses reacted quickly to the drought conditions: https://t.co/9MlRj861Av
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Hot off the press! Latest work by @mia_s_lee characterizing active viruses of ammonia-oxidizing archaea in soil using a new twist on DNA-SIP 😀 https://t.co/EyBKTT9d1G
@SieraVirus @graemewnicol @CHazard99
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Viral communities across grasslands aren't uniform & understanding those dynamics could lead to better insight into how bacteria in soil will react to drought & climate changes, according to research from @jemersonmicro @cmsantosm published in @PNASNews
caes.ucdavis.edu
Viral communities across a grassland area are not uniform, and understanding viral dynamics could lead to better insight into how bacteria in soil will react to drought and other climate changes,...
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What great timing for twooting about our new paper on soil viruses. I have elected to get some help from a mastodon and a bird. https://t.co/l5q4SnidZL (1/7)
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This work is part of the @doescience "Cross-Kingdom Interaction" project led by @Firestone_Lab. Thanks to all team members and, especially, to co-authors Rina, Maggie, @Jeffinerca, Mary, and @jemersonmicro
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