RT @kauralasoo: And here is one more preprint from the lab. I promise that this is the last one for this year!.

RT @Cambridge_Uni: Cambridge and @GSK announce a new five-year collaboration aiming for improved outcomes for patients with hard-to-treat k….

RT @amymariemason: It's university admission season. If you are/know someone from a disadvantaged background applying to do Maths at @Unio….

While sffdr is FDR-based, we calculate p values so GWAS practioners work with familiar quantities. Want to give it a go? Download the R package from . /ends.

sffdr power gain is study dependent, but was equivalent to 60% increase in sample size in a large study of obesity-related traits, and raised number of discoveries from 2 to 10 in study of rare disease EGPA. Another important point: /2.

RT @MRC_BSU: A new method for understanding how changing proteins link to disease risk has been developed by.@chr1swallace, Ichcha Manipur….

RT @IchchaManipur: The CoPheScan R package is now on cran and GitHub : .

With the simpler structure, we can also extend the model to learn prior probabilities for the different hypotheses, possibly conditional on trait-level covariates.

We adapt the coloc approach to the case where a causal variant is known with certainty for one trait, and we want to ask if it is also causal for another. This means we can extend the approach to cases such as loss of function variants.

RT @anderson_carl: Come work with Ewan, myself and many others on a really exciting host pathogen interaction GWAS. The dataset is really r….

RT @JohnSnowSociety: It's that time of year: October's Pumphandle Lecture poster for your noticeboard📜:. If you po….

RT @stats_ci: The MRC Biostatistics Unit offers a NEW in-person short course on "Bayesian Methods for Clinical Trials".😍.For further course….

First time COVID and it's awful. All this time wasted feeling rubbish, not even able to read. Can anyone suggest something good to listen to?.

RT @stats_UCL: A fully funded PhD studentship covering home fees and a stipend is available in a project supervised by Prof Ricardo Silva.

Yes @officialbarnesy ! The most astute commentary on the real issues behind #Linekergate instead of the media focus on political comment. 👏👏👏.

you have a small set of 20 findings identified with through some testing procedure with estimated FDR < 0.05. You subsequently test ten of these in independent data and confirm the findings. Does that mean the FDR in the other ten is now 0.1?.

RT @mark_toshner: Sir Paul Nurse independent report. This is quite a read if you are interested in UK science. Recommends nothing short of….

RT @RoychoudhuriLab: We’re hiring! We seek a post-doc to break new ground in the fields of T cell biology, immune regulation and immunosupp….