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Ane Appelt Profile
Ane Appelt

@cancerphysicist

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Physicist, cancer & radiotherapy researcher, trialist, data nerd. Professor of Clinical Medical Physics at Rigshospitalet & DTU, Copenhagen, DK #radonc #medphys

Copenhagen, Denmark
Joined August 2016
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@cancerphysicist
Ane Appelt
3 years
Look! Look! 😲😱 That’s my cross-stitch on the front page of @IJROBP! I’m SO grateful to @sueyom & team for picking my depiction of a lung SABR plan for the special issue on oligometastatic disease #radonc #medphys @Mat_Guc @SalmaJabbour1 https://t.co/aRMLLuZh3z
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@cancerphysicist
Ane Appelt
1 month
Now that the #ASTRO25 exhibition has closed, I can pick the greatest innovation spotted on the floor. And no, it isn’t MRI-PET-CT guidance, theranostics, AI-guided treatments, or upright RT. But it’s fabulous! 🤩 #radonc
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@cancerphysicist
Ane Appelt
1 month
Also, just in case you’re interested, I’ll be talking about dose accumulation for #reirradiation today at 12:45 in room 154 with some great colleagues 😊 (Did I match my dress to my slides? No comments)
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@cancerphysicist
Ane Appelt
1 month
Still here!! Still want to say hello! I’ve dressed up in my most colourful dress today, so you have absolutely no way of missing me 😂 #ASTRO25 #radonc #medphys
@cancerphysicist
Ane Appelt
1 month
I’m at #ASTRO25! And it feels like I don’t know a soul, so please do come up to say hi if you spot me - it’s kind of a weird feeling 😉 (Rare X check in from me, since it seems like the North American #radonc community are still holding out here?)
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@cancerphysicist
Ane Appelt
1 month
I'm sure there are a lot of complexities that I'm not capturing here. But in the setting of high quality IMRT, optimised on modern OARs, IMPT *may* not be necessary for this patient population #ASTRO25 #radonc
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@cancerphysicist
Ane Appelt
1 month
TORPedO had extensive RTQA, and careful RT protocols for both arms, including optimisation of swallowing function related OARs. I’ve got great confidence that the TORPedO IMRT plans & delivery represent truly optimised state-of-the-art photon treatment #radonc
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@cancerphysicist
Ane Appelt
1 month
TORPedO was negative on every measure explored (with a slight favouring of IMRT for some!), including clinician and patient reported outcomes, OS, and PFS. And no indications of a signal in an ‘enriched’ (high dNTCP on comparative planning) cohort #ASTRO25 #radonc
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@cancerphysicist
Ane Appelt
1 month
Personally, I note that: 🔹The US trial saw significant insurance approval issues and large proportion of cross over 🔹Enrolment started over a decade ago, when IMRT optimisation & OARs were very different from today 🔹The fnding of OS benefit was very unexpected
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@cancerphysicist
Ane Appelt
1 month
Protons for oropharyngeal cancer? Following the presentation of TORPedO results at #ASTRO25, it seems like it might come down to whether you believe in UK or US data - or, in the words of Dr Takiar, the session discussant, 'whether you believe in a round or a flat earth' #radonc
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@cancerphysicist
Ane Appelt
1 month
Main learning point from first full day at #ASTRO25: I never thought I’d say this, but us Europeans need to up our coffee game!☕️ #radonc #coffeechallenge (To be fair, it was a very sweet concoction which no European barista would be caught dead serving 😂)
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@5_utr
M. Bolton
1 month
🚨 Primary results for the phase III trial of Toxicity Reduction using Proton Beam Therapy for Oropharyngeal Cancer (TORPEdO; CRUK/18/010) Endpoint: G3 weight loss, G-tube dependence OR 2.8 (0.8-10.4) for IMPT! Protons are likely worse in this setting #ASTRO2025
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@cancerphysicist
Ane Appelt
1 month
I’m at #ASTRO25! And it feels like I don’t know a soul, so please do come up to say hi if you spot me - it’s kind of a weird feeling 😉 (Rare X check in from me, since it seems like the North American #radonc community are still holding out here?)
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@cancerphysicist
Ane Appelt
3 months
AAPM, here I come! Only my 2nd time ever, and 7 years since I last went 😳 Have acquired a few more grey hair & wrinkles in the meantime, but still excited to hear what’s happening on the other side of the pond. And please all reach out if you want to meet up! #medphys
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@cancerphysicist
Ane Appelt
4 months
My inaugural lecture as Professor of Clinical Medical Physics @Rigshospitalet @DTUtweet will be on the 6th Oct at 3pm in Auditorium 1, Rigshospitalet, Copenhagen It would be lovely to see a lot of familiar faces, for the lecture and for the reception afterwards #medphys #radonc
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@jonas_willmann
Jonas Willmann, MD
5 months
☢️🚨 Everything you wanted to know about reirradiation (and maybe even more) — now out in @CACancerJournal! A massive effort led by @arnaud_beddok & @NAndratschke, powered by an international all-star team 🌍 Grateful to everyone who contributed! 🙌 #RadOnc @OncoAlert
@CACancerJournal
CA: A Cancer Journal for Clinicians
5 months
Reirradiation (reRT) is reshaping cancer care—offering hope for recurrent tumors w/ advanced precision techniques like IMRT & SBRT. Multidisciplinary care, imaging, and innovation are key. New #OpenAccess review by Andratschke et al: https://t.co/T41ik4rEsa @OncoAlert #RadOnc
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@cancerphysicist
Ane Appelt
6 months
Oh well, that didn’t quite go to plan … Got 9 hours of solid sleep and a shower, but now stuck in Cologne waiting for a replacement bus. At least I’ve got good company! #ESTRO25
@cancerphysicist
Ane Appelt
6 months
My feet are shattered by too much walking in heels, and I'm functioning on about 15 hours of sleep over the last five days. So now hanging out in a cool little cafe, trying to keep awake before boarding the night train to Brussels🚆 See you all in Stockholm next year #ESTRO25
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@cancerphysicist
Ane Appelt
6 months
My feet are shattered by too much walking in heels, and I'm functioning on about 15 hours of sleep over the last five days. So now hanging out in a cool little cafe, trying to keep awake before boarding the night train to Brussels🚆 See you all in Stockholm next year #ESTRO25
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@cancerphysicist
Ane Appelt
6 months
This was also my very first conference with my partner attending - and we even had a joint study to present 😊
@cancerphysicist
Ane Appelt
6 months
How do patients prioritise different aspects of non-operative rectal cancer treatment? We conducted a prospective, multicentre study alongside a clinical trial; asking rectal cancer patients undergoing definitive RT to help us understand treatment preferences #ESTRO25 #RadOnc
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@cancerphysicist
Ane Appelt
6 months
I gave a total of 5 talks, attended & chaired numerous meetings, made it to too few of the scientific talks (🙏 online recordings!), and saw so many friends and colleagues that I have lost count a long time ago. I even managed to meet a few new people (@NiuSanford!) #ESTRO25
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@cancerphysicist
Ane Appelt
6 months
I got to catch up with my partner in crime (i.e. all things #reirradiation) @elivaos, who gave a brilliant - as always - talk on image registration for reRT dose accumulation today #radonc #medphys #ESTRO25
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@cancerphysicist
Ane Appelt
6 months
We got to present our innovative #reirradiation treatment planning solution, developed in close collaboration with RaySearch - and we saw the near-final implementation in RayStation. I can't believe that this may soon be available for clinical treatments! https://t.co/xmGvsofK67
@cancerphysicist
Ane Appelt
6 months
Things that make me happy: Seeing an RT planning & evaluation solution for #reirradiation that I’ve helped develop in its (nearly) final version. Amazing work by the RaySearch team and my @CRUKRadnetLeeds colleagues. Probably highlight of #ESTRO25 so far for me 😍
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