Aaron Boes
@boeslab
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Neurologist & Neuroscientist: Lesion Mapping | Lesion Network Mapping | Brain Stimulation
University of Iowa
Joined January 2022
RT @DrCoreyKeller: Brain stimulation helps millions with depression, but we still don't know HOW it works. Enter TMS-iEEG: directly measure….
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New lesion study of dyskinetic CP. Wondering how similar / dissimilar network is to lesion associated dystonia, which implicated SCAN?.
onlinelibrary.wiley.com
Objective Dystonia is a movement disorder defined by involuntary muscle contractions leading to abnormal postures or twisting and repetitive movements. Classically dystonia has been thought of as a...
Marcelino and Al-Fatly et al. report literature-based lesion network mapping of dyskinetic cerebral palsy. Grey matter lesions are the most common MRI finding; the motor thalamus is a converging node of a wide functional network. Read at
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The most fun image & video creation tool in the world is here. Try it for free in the Grok App.
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Very excited to have Mark Bowren join our U. of Iowa faculty in July. Check out his open RA and post-doc positions. Awesome opportunity for anyone interested in lesion research and virtual lesions using a novel ultra high frequency intracranial stim. Exciting stuff to come….
In ~2 weeks I'll begin launching my lab, the Brain Lesion and Neuromodulation Lab! I'm looking to fill 2 roles: 1 RA & 1 postdoc. If you're interested in intracranial electrical stimulation, lesion-deficit mapping, and/or neuropsychology, reach out! Official postings to come.
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It has been a team effort that wouldn't have happened without major contributions from each of the authors. Have to give special shout out to @m_brzus for leading the engineering efforts. That is Dr. Brzus as of today, PhD in engineering. Big things to come from him!.
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Our lab has spent the last few years developing a fully automated tool for predicting personalized outcomes from stroke that incorporates lesion location. Our hope is that it bridges lesion research and clinical neurology. Check it out: .
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Great news! Congratulations Mark. Thrilled to have you join the faculty.
A dream of mine has come true: I've accepted an offer to become a tenure-track assistant professor & clinical neuropsychologist at the University of Iowa! I'm honored to help carry on the legacy of neuropsychology and cognitive neuroscience that has been established here.
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RT @PinesAndrew: What brain regions are involved in causing psychotic symptoms?. Take a moment away from the existential dread about the fu….
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RT @ZanatyMario: In @elife: Neuromodulation with Ultrasound: Hypotheses on the Directionality of Effects and a Community Resource https://t….
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RT @ndosenbach: In the action-mode, arousal is heightened, attention focused externally, and plans are converted to goal-directed movements….
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Does TMS delivered to the dlPFC elicit a response in the subgenual ACC?. New work with intracranial EEG says yes! .@NickTrapp13 @DrCoreyKeller @jingjiang_psy. Preprint here: .
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New U. of Iowa neuropsychology faculty position posted . Come join Dan Tranel and team and contribute to our rich tradition of lesion research. @UIowaNeuro @IowaNeurology .
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That's it for habenula. If you’re wanting to dive in further I’d start with these:. Pretty thorough 2020 review:. Depression:. Lateral habenula in the pathophysiology of depression Habenula DBS:
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Clinical relevance? Its overactivity is heavily implicated in depression – numerous animal models + human evidence. Effective depression treatments associated with reduced habenula activity. Case studies suggest habenula DBS can treat depression. Prospective trials needed.
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The habenula is active when rewards don’t materialize as expected. It inhibits release of DA and 5HT, and facilitates the despondency that ensues - anhedonia, amotivation, avoidance.
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I’ll focus on lateral habenula - a key hub between the forebrain and monoaminergic systems. Input comes from the forebrain (limbic + GPi of basal ganglia) via stria medullaris tract. Outputs modulate (inhibit) dopamine (DA) and serotonin (5-HT) in the midbrain.
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The habenula is a tiny, pea-sized structure that sits atop the pineal gland. On coronal images you can find it bulging into the 3rd ventricle right above the posterior commissure.
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Everyone knows about reward systems in the brain. Today we meet the hero of the often-neglected anti-reward system. Habenula anatomy and function…
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What do you have for favorite neuroscience books read this year, #neurotwitter? Looking for some good reads over holidays. I'll start with this one. Leave it to a non-neuroscientist to write one of the best neuro books I've read in years. Thanks to @andreashorn_ for rec
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RT @foxmdphd: Is there a brain circuit for #schizophrenia? Press release from @MassGenBrigham on work by @edmakhlouf @shansiddiqi out tod….
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