Zorgwekkende studie die blootstelling
#glyfosaat
koppelt aan hersenschade. Concentratie glyfosaat in urine correleert aan serum NFL (neurofilament light protein), betrouwbare marker voor
#Parkinson
,
#Alzheimer
,
#ALS
in algemene populatie, niet eens mensen die werken met glyfosaat
Gisteren heeft iedereen kennis kunnen nemen van het kabinetsbesluit t.a.v. de hernieuwde goedkeuring van
#glyfosaat
door de Europese Commissie. Concreet zal Nederland zich onthouden van stemming. Mijn reactie hierop staat in de 3 bijgaande pagina's.
#parkinson
Vandaag is een belangrijke motie aangenomen in de Tweede Kamer waarin minister Adema wordt opgedragen te stemmen tegen de Europese verlenging van de toelating van
#glyfosaat
. Ik ben hier bijzonder verheugd over, om de volgende redenen.
Nog maar 1x: er is geen enkele zekerheid dat pesticiden, ook niet
#glyfosaat
-veilig zijn mbt risico op
#Parkinson
& andere neurodegeneratieve ziekten. Conclusie wordt breed gedeeld door alle deelnemers aan de werkconferentie, oa EFSA, RIVM, Ctgb, internationale experts
#consensus
Because 1 dance is not nearly enough to end
#Parkinson
, I add another one to
#dancepartyPD
/
#dance4parkinsons
/
#dopaminedancePD
initiative. Again highly appropriate: “No Limit” is tribute to admirable/inspirational resilience of people with Parkinson & their near ones!
Today=World Parkinson’s Day. To express my allegiance to people with
#Parkinson
& their near ones, I join the worldwide
#dancepartyPD
/
#dance4parkinsons
/
#dopaminedancePD
initiative. And what better song than “Let’s stick together” - because this is only way to stop Parkinson.
Geslaagd optreden in TV programma
@DeHofbar
gisteravond op
@NPO2
waar ik commentaar gaf op de relatie
#pesticiden
&
#Parkinson
, nu extra actueel gezien uitspraak rechter die vanuit
#voorzorgsbeginsel
het gebruik pesticiden in de lelieteelt heeft verboden.
De enorme impact van
#Parkinson
op leven van mensen, beschreven op indrukwekkende wijze door Merel van Vroonhoven. Het is echt één van de akeligste dingen die een mens kan overkomen. En het is een ziekte die minstens deels te voorkomen is, als we maar de juiste stappen zetten.
Published wonderful paper in
@TheLancetNeuro
about clinical pearls in movement disorders. We asked experienced clinicians about specific clinical tests or therapies which they learned from their mentors, now use in their clinical center & which they pass on to their own students.
Gisteren ontvingen Marten Munneke & ik beiden een koninklijke onderscheiding. Totale verrassing! Extra bijzonder omdat lintje is toegekend op voorspraak van mensen met
#Parkinson
. Fantastisch dat we tegelijkertijd dit lintje kregen. We hebben alles van meet af aan samen gedaan.
1/2 Humbled, proud and, above all, extremely thankful that I was awarded with the prestigious NWO Stevin Prize today-the highest recognition in the Netherlands for scientists who have achieved an exceptional success in the area of knowledge exchange and impact for society.
1/3 One of the most exciting studies I ever participated in! In Park-in-Shape trial, we previously demonstrated in paper in
@TheLancetNeuro
that
#aerobic
#exercise
3x/week for 30-45 min at 70-80% maximum cardiac output was associated with stabilization of motor symptoms.
Bought a
#litter
picker and now take this with me on my hikes. Amazing how much
#garbage
you collect.... Let’s all start doing this and make our world a bit cleaner together!
#climate
#ClimateChange
To all my followers, but especially to everyone living with
#Parkinson
disease or parkinsonism, and to all those many people who are fighting alongside with them:
Merry Christmas & a Happy, Healthy New Year, filled with your own dose of
#Hopamine
!
Wow … Because I recently received the prestigious
#Stevin
award in the Netherlands,
@TheLancetNeuro
Neurology has now published an absolutely beautiful profile about me and the work of our team. Many thanks to Adrian Burton for phrasing this so wonderfully.
@NWONieuws
Our new publication in the
@journal_PD
provides a comprehensive and compelling summary of all the evidence that supports the growing recognition that
#Parkinson
disease is largely an environmentally caused condition.
Open access paper:
Vandaag ben ik om 16.45 te gast bij EenVandaag op NPO Radio 1 en rond 18.15 bij hetzelfde programma op televisie, om te praten over het voorgenomen Europese besluit om het gebruik van
#glyfosaat
(
#Roundup
) te verlengen met 15 jaar.
Zó leuk: vanavond gast
#top2000agogo
als “lijstduwer”. Uitleggen waarom Rob de Nijs veel hogere plek verdient. Ode aan deze fantastische artiest die ondanks uitdagingen
#Parkinson
Ziggo dome ontroerde. Ook eerbetoon aan alle mensen met Parkinson. 19.30u
@NPO3
@diederikebbinge
Dit stuk
@nrc
vat nog eens grote zorgen rondom veiligheid
#glyfosaat
samen. Ja, er is veel onderzoek gedaan naar toxiciteit maar goede studies ontbreken als het gaat om risico’s op
#Parkinson
& andere neurodegeneratieve ziekten. Diverse ernstige tekortkomingen in toetsingskader
In
@nrc
een stevig pleidooi van neuroloog
@basbloem
om
#glyfosaat
te verbieden, want: "Er is een biologisch plausibel verband tussen glyfosaat en parkinson". Vrijdag stemmen de lidstaten. Nederland zal zich 'onthouden'.
Brilliant moment: Joop Alberda, my former coach of Dutch national
#volleyball
team <18-and later head coach of Dutch Olympic gold team in 1996 in Atlanta-visited me in
@radboudumc
because of my recent Stevin award. Of course we took the opportunity to practice a bit together 😁👍
My predominant concern around
#glyphosate
continues to center on fact that current regulatory actions provide inadequate insight into risk of
#Parkinson
& other neurodegenerative disorders. In opinion paper in Le Monde we identify multiple drawbacks in screening procedures.
3/3 This is 1st time that such
#neuroplasticity
is shown in persons with
#Parkinson
. We also found improvements in cognition. Everyone living with Parkinson should hopefully use these findings as massive incentive to build up your own
#exercise
regime!
Importance of new Technical Brief on
#Parkinson
by
@WHO
is underlined by compelling editorial in
@TheLancetNeuro
. We must act together NOW to stop the Parkinson pandemic. In the meantime we must tackle inequalities in access to care & optimally support everyone affected globally.
1/2 Zeer geslaagde
#Pauw
special gisteren over
#Parkinson
. Veel respect voor Annelien Oosterbaan, Rob de Nijs & Ernst Daniël Smid die persoonlijke verhaal deden. Gesproken over belang Parkinson niet te “verstoppen” maar erover praten & behandeling zoeken
I have seen many posts by people who were eager to read the new Seminar on
#Parkinson
Disease that was just published in
@TheLancet
. The free downloadable version is here (limited time only)
1/2 Indrukwekkend artikel in
@DeGroene
Amsterdammer over de gezondheidsrisico’s van
#glyfosaat
(
#roundup
). EFSA-de Europese instantie die hierover gaat-erkent dat ze niet met zekerheid kunnen stellen dat glyfosaat veilig is als het gaat om het risico op de ziekte van
#Parkinson
.
Our paper in
@GreenJournal
provides pragmatic approach to functional
#gait
disorder-both common & debilitating. We provide sign-based approach larded with illustrative videos as basis for targeted diagnosis & subsequent treatment. Patients deserve this!
@FNDSociety
@jonstoneneuro
#ThrowbackClinic
today - saw a patient who came all the way from India to see me. Felt like the good old days to review the MRI scan of the brain this way 😁!
There is concern that
#COVID19
infection (definitely a neurotropic virus) might cause irreversible parkinsonism. We offer counterargument:
#stress
associated w/ acute COVID19 infection can unveil underlying
#Parkinson
that was already present with
#prodromal
signs for years.
1/2 New rodent study shows that
#glyphosate
can enter the brain, and trigger a process of
#neuroinflammation
. Together with earlier work suggesting a possible link between glyphosate and neurodegenerative disorders like
#Alzheimer
and
#Parkinson
, this is further cause for concern
First copies of our book “Ending Parkinson’s Disease” arrived today. Deals with
#Parkinson
#pandemic
, its causes, what to do to stop this growth and how to deliver better care, for & with people w/ Parkinson. All proceeds to Parkinson research.
#endingPD
Today is World
#Parkinson
Day. A moment to appreciate how hard we must work together to find much needed solutions.
I promise to keep working on this as hard as I can, together w/ our wonderful team & many outstanding colleagues worldwide.
WE WON’T STOP UNTIL PARKINSON STOPS!
Honoured for been appointed-despite being very Dutch-as Fellow of Royal College of Physicians of Edinburgh. Will now go through life as Bas Bloem, MD, PhD, FRCPE. Perhaps long-standing love of my family for Scotland & Edinburgh-exemplified by my sons-supported my nomination 😄!
Vanavond 18.15 bij
@EenVandaag
, reageren op 1e uitkomsten SPRINT, groot Europees onderzoek naar
#pesticiden
; meer dan 100 verschillende daarvan aangetroffen in oa huisstof. Ook in bloed & ontlasting boeren/omwonenden. Ga vanavond in op betekenis volksgezondheid, oa
#Parkinson
.
Incredibly proud to announce my election as member of the prestigious
@_knaw
(Royal Netherlands Academy of Arts and Sciences). Look forward to representing
@radboudumc
and
@Radboud_Uni
, and to contributing to the (inter-)national discussion about the future of
#science
!
Vond deze reclamefolder van
@groenlinks
in de bus en realiseerde me dat dit een klassieke “Stroop” test is uit de neuropsychologie: het woord Groen is geschreven in rood, en het woord Links staat rechts.
Er is uitvoerig wetenschappelijk bewijs dat verband tussen
#Parkinson
&
#bestrijdingsmiddelen
aantoont. Zowel epidemiologisch als dierexperimenteel. Ook
@rivm
bevestigt deze associatie in het rapport. Veel relevante literatuur staat samengevat in ons boek De Parkinson Pandemie.
Ministerie LNV zegt hier, als ik het goed begrijp, dat er geen aanwijzingen zijn voor een relatie tussen onze pesticiden en Parkinson. Dus geen reden voor Schouten om het voorzorgbeginsel toe te passen. Maar die aanwijzingen zijn er toch gewoon wél?🤷🏻♀️
@basbloem
@LeonieVestering
Great new book on the benefits of
#exercise
for persons with
#Parkinson
, written by three absolute experts in the field. Happy to have contributed the foreword for this book. Very much worth reading!
1/5 One of the most thought-provoking papers in which I ever participated. Jos Voeten, who lives with
#Parkinson
himself, asked me the provocative question whether there is such a thing as a “silver lining”, i.e. an upside, to having Parkinson’s disease.
#silverlining
Deze uitspraak van het Europese Hof van Justitie is in ieder geval belangrijke erkenning dat niet alle procedures sluitend inzicht geven in veiligheid/risico’s van thans gebruikte
#pesticiden
. Hetzelfde geldt voor risicobeoordeling t.a.v Parkinson.
1/2 Important new study from California links exposure to
#pesticides
(that were previously already associated with an increased risk of developing
#Parkinson
disease) to a more rapid disease progression once people already have developed Parkinson's.
Nòg zo’n bijzonder moment: bos tulpen ontvangen van Groene Bloemen, geheel onbespoten zonder gebruik van
#pesticiden
. Extra symbolisch want de
#tulp
is het symbool van de internationale strijd tegen
#Parkinson
.
My lecture on the WHY of
#tracking
in
#Parkinson
disease at the 6th World Parkinson Congress was well received. Time to bring Parkinson’s care & research back home.
#wpc2023
Proud of this article that we wrote for
@lemondefr
and where we urge Marc Fesneau, the French minister of Agriculture, to vote NO against the renewal of
#glyphosate
. We offer compelling arguments to motivate that decision, including concerns about risk of
#Parkinson
.
#Glyphosate
: «En tant que médecins spécialistes des maladies neurodégénératives, nous avons trois conseils pour le ministre de l’agriculture M. Fesneau» par
@basbloem
&
@TjitskeBoonstra
1/2 Important message: research in
#Parkinson
field is incomplete without involving
#patientresearchers
right from outset, in design, execution & interpretation of studies. Written together with 2 excellent patient researchers (Anne Donnelly & Margaret Sheehan).
@journal_PD
Just published Commentary in
@journal_PD
describing “hidden” impact of
#corona
crisis on people with
#Parkinson
.
#COVID19
threat extends well beyond immediate concerns (infection, pneumonia) but also involves negative effects of
#stress
, physical inactivity and social
#isolation
.
Mooi geslaagd interview met
@PlusMagazine
over de groei van
#Parkinson
& de oorzaken daarvan, en over onze missie om Parkinson de wereld uit te helpen.
1/2 Excited to share our new paper where we assess whether wearable sensors objectively monitor response fluctuations in persons with
#Parkinson
in real life. We recorded people with Parkinson in & around own homes, while they performed their usual activities.
#Wearables
When lightning strikes twice
If you have
#Parkinson
/parkinsonism then please look at this video. We are interested in specific combinations of symptoms that cause extra problems in daily life. We want to understand this better by learning from you so we can improve our services!
Simply wonderful to be back at the Centers of Excellence meeting of the
@ParkinsonDotOrg
in Boston - and to meet old friends again. Impressed with the amazing growth of the Foundation, and the tangible impact they are having on people with
#Parkinson
worldwide.
@MichaelOkun
Prof. Van Laar, die in Nederland onderzoek heeft gedaan naar Parkinson & pesticiden, refereert ook aan internationale meta-analyse (Gunnarsson & Bodin 2019) waarin mensen na beroepsmatige blootstelling aan pesticiden 50% hogere kans op Parkinson hadden.
@EFSA_EU
Wat mij betreft reden om terughoudend te zijn met verlenging
#glyfosaat
. Eerst juiste experimenten uitvoeren, niet door industrie zelf maar door onafhankelijke wetenschappers die ALLE bevindingen publiceren in internationaal tijdschrift, na kritische beoordeling door referenten.
Excellent start of 2024 with this important publication in the highly ranked journal Nature Reviews Neurology. We offer a balanced, nuanced perspective on the recent decision to extend marketing authorization for the use of
#glyphosate
within the EU for another 10 years.
In this new paper we review evidence on relation between
#pesticides
& other environmental
#toxins
and risk of
#Parkinson
disease. We reiterate why current regulatory actions provide insufficient insight in neurotoxicity and risk of Parkinson & other neurodegenerative disorders.
1/2 Vandaag belangrijk rapport
@rivm
verschenen, met oproep tot aanpassing toelatingsbeleid
#bestrijdingsmiddelen
. Specifiek wordt gevraagd om aanpassingen van de criteria, om gericht te kijken naar risico
#Parkinson
,
#Alzheimer
of
#ALS
. Dit gebeurt nu nog niet!
Our latest study shows that not all people w/ genetically defined risk of future development of
#Parkinson
are aware of possible benefits of
#exercise
to mitigate that risk. And (stunning!), even when these at risk people do have that knowledge, many of them still don’t exercise!
In Australia now for series of lectures, first Sydney, then Melbourne. Did 3 talks for colleagues but today is highlight of the trip - speaking to people with
#Parkinson
& their near ones.
Great many thanks to my friend
@profsimonlewis
Lewis for wonderful, legendary hospitality!
Nav grote schenking 10 miljoen uit Engeland aan
@ParkinsonNet
ben ik vanavond live te gast bij
@NadiaMoussaid
in
#laatop1
. Ga vertellen hoe we vanuit
@radboudumc
nieuw zorgmodel implementeren & evalueren, eerst voor
#Parkinson
maar breed toepasbaar in Nederlandse gezondheidszorg!
Today Rui Araujo successfully defended his
#PhD
dissertation on the
#art
of clinical
#neurology
. He received the prestigious and exceptional CUM LAUDE predicate (with distinction) - so highly deserved. Congratulations Rui, I truly feel like a proud (academic) father today !!
In this important Comment in Lancet Planetary Health, a highly ranked, independent, and peer-reviewed journal, we now summarize our concerns around
#glyphosate
and
#Parkinson
disease. We have two main concerns.
Highly recommended: this amazing supplement of
@GreenJournal
dedicated entirely to cunning new plans for trials aiming to
#prevent
#Parkinson
. Our own group contributes with a review on the pros and cons
#exercise
as disease-modifying intervention.
Crucial paper by 6 power women on vexing unmet needs of
#women
w/
#Parkinson
. Crucial roadmap to better understand role of
#sex
&
#gender
in Parkinson, identifies crucial gaps in knowledge for care & science, defines clear goals to develop unique services to better support women!
Extremely proud & honored to have won the prestigious Tom Isaacs Award, together with the amazing Simon Stott
@ScienceofPD
. Enormous incentive to keep pushing for better world for persons with
#Parkinson
& continue the quest for a cure that Tom Isaacs &
@CureParkinsonsT
started
Today on World Parkinson Day, join
@ParkinsonsUK
in their efforts to create better world for people with
#Parkinson
. Join their special event today 11 am UK time via . Many thanks to the wonderful
@pdinfocus
for his brilliant cartoons of the speakers.
2/2 We demonstrate that early
#levodopa
start has no disease-modifying effect in early
#Parkinson
but with much better quality of life & without marked adverse effects. Findings may help to alleviate levodopa “phobia” among patients & physicians.
#clinicaltrial
@amsterdamumc
I continue to be amazed by impressive commitment to
#exercise
shown by people w/
#Parkinson
. Compelling examples include e.g.
#boxing
,
#dancing
,
#running
.
Now look at this inspiring video on walking
#football
, led by Paul Nicholls & friends. Great!!
1/2 Hoe een klein meisje een ware gigant kan zijn: Fenne (9 jaar oud pas!) heeft met verkoop zelfgemaakte cupcakes-SUPERLEKKER-ongelofelijke bedrag van 550 euro opgehaald, tbv onderzoek naar
#Parkinson
. Zo steunt zij haar opa die deze ziekte heeft.
@radboudumc
@Radboudfonds
1/2 Happy & proud that Lorraine Kalia, excellent neurologist/scientist from Toronto, is new co-editor-in-chief
@journal_PD
. Lorraine has outstanding track record, particularly in translational neurology. We are building plans together to take journal to next, even higher level.
Based on insights from the field of
#genetics
, we provide a new perspective in
@journal_PD
as to why
#Parkinson
disease is predominantly an environmentally driven condition.
1/2
@kalialabs
& I are very proud that
@journal_PD
will take the open road: starting now, JPD transitions to a Gold
#OpenAccess
publication. This means all articles published will be immediately and permanently freely available online for readers to view, download, and share.
@MvAndel
dag Michiel, had je toevallig gekeken naar de auteurs van dit stuk (bijlage)? Bij een kwalitatieve review - wat dit is - zou je graag onafhankelijkheid willen zien, zoals in de vele andere studies die ik citeer ... Een dergelijke belangenverstrengeling vind ik heel ongewenst.
Straks om 22u live in de uitzending bij
@HumbertoRTL
op
@RTL4
- nav de
#Stevinpremie
die ik namens ons team in ontvangst mocht nemen afgelopen vrijdag. Bijpraten over ons werk tot nu toe, en vooral over nieuwe plannen om doorbraken voor mensen met
#Parkinson
te realiseren!
1/3 One of the nicest papers I wrote in years. Little tribute to
#art
of
#medicine
. Excellent input of my wonderful PhD student Rui Araujo, my friend & clinically amazing colleague Bart vd Warrenburg and two my most inspiring neurological mentors (Prof Tony Lang & Prof
@ajlees
)
Zorgwekkend: veel jonge fysiotherapeuten stoppen snel oa vanwege ontbreken passende vergoeding. Ongelofelijk jammer want
#fysiotherapie
bij bv mensen met
#parkinson
helpt om vallen & letsel te voorkómen, en zorgkosten gaan aanzienlijk omlaag!
@KNGF_Fysio
New study links
#glyphosate
to neurological damage-correlation between elevated levels of urinary glyphosate & increased concentrations of serum neurofilament light protein (NFL) in adult general population in US (so not even persons working professionally with glyphosate!).
Our paper on
#trichlorethylene
(
#TCE
) as a possible (and invisible) cause of
#Parkinson
just came out in
@journal_PD
. TCE is a colorless liquid that has been widely used, e.g. to remove paint, to clean engines, to degrease metal, to decaffeinate coffee and to dry clean clothes.
Our new Seminar on
#Parkinson
in
@TheLancet
takes very individualized, person-centered approach. Word “patient” appaers only twice (slip of the pen) in 20 full pages. Instead, we consistently speak of persons, people or individuals with Parkinson disease.
Hard to express just how proud I am of Josefa Domingos who successfully defended her
#PhD
thesis on community-based
#boxing
for persons with
#Parkinson
. Wonderful work showing the importance of organising
#exercise
in the people’s own living environment!