Ariel Zeleznikow-Johnston
@ariel_zj
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Neuroscientist, author | New book on abolishing death: https://t.co/jLDd8krbUv | Currently a postdoctoral fellow in @conscious_tlab
Melbourne, Victoria
Joined January 2022
'The Future Loves You: How and Why We Should Abolish Death' is out now! Read it, listen to it, steal it, ban it, review it, trash it, love it, etc
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Nice highlight of part of our talk!.
What does that mean to say “I’m a self?” When I’m having this subjective experience right now, how does that work? How does my brain give rise to consciousness? And what makes someone the same person across different time points?
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RT @AspirationNeuro: Join our Memory Decoding journal club on TUESDAY: #neuroscience #memory #decoding #aspirationa….
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Read the full outline of the Brain Preservation Foundation's plans for Standards and Accreditation here:.
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To address this, the Brain Preservation Foundation intends to establish quality standards and an accreditation program to fill this gap, to help transition high-quality brain preservation from laboratory research into credible clinical practice. 3/4.
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Historically, there have been no standardized quality metrics or independent third-party evaluation of preservation providers, making it difficult for patients to assess different procedures or for the field to demonstrate scientific legitimacy. 2/n.
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If proponents of brain preservation/biostasis/cryonics want the field to become mainstream science, we need standards for what counts as a well-preserved brain. To become mainstream medicine, we need third-party reviews and accreditation. The BPF wants to make this happen. 1/n
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RT @AspirationNeuro: Join tomorrow 3 pm PDT! Systems consolidation reorganizes hippocampal engram circuitry - #neur….
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New paper showing cryopreservation & subsequent functional/electrophysiological recovery in both . 1. hippocampal slices .2. partially in whole mouse brains (!). Great discussion of how to deal with osmotic shrinkage too. @cradle_health @huntercoledavis @LauraDeming @RScryo
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Much more in the actual paper, including:.-general neuroscientists vs engram expert response breakdown.-timeline estimates for when whole-brain emulation might be possible.-discussion of caveats. 6/6.
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Despite disagreement, the community assigns substantial probability to long-term memories only depending on static brain structure preservable by modern brain preservation techniques. Good news for those interested in brain preservation for life extension!. 5/6
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To take this further, we asked what probability neuroscientists thought .1) at least one memory could theoretically be decoded from static brain structure (i.e. a preserved brain).2) all memories could theoretically be decoded, e.g. by making a whole-brain emulation. 4/n
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If long-term memories are stored in synaptic ensembles, rather than dynamic processes like electrophysiological activity, then maybe they could theoretically be read out from a static snapshot of the brain's ultrastructure?. Here neuroscientists are less certain. 3/n
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In a review from 2015, Mu-Ming Poo stated “There is a clear consensus on where the memory engram is stored—specific assemblies of synapses activated or formed during memory acquisition”. Most, but not all, neuroscientists agree. 2/n
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What do neuroscientists think is the physical basis of long-term memory? . Could memory theoretically be read out from a static snapshot of brain structure?. Our survey of hundreds of participants has just been published!. 1/🧵
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Melbourne people,. On Wed 27 Aug, I'll be giving a talk at the State Library (Wheeler Centre) about:.-why we die.-how by preserving someone's brain, we can stop them from dying.-many other weird and fun things from my new book. @wheelercentre #NowOrNever
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