Excited to share our new paper in Vaccine! We surveyed US adults on #mpox Clade Ib awareness, attitudes, and #vaccine intent. Findings: 58% would vaccinate if recommended—up from 2022—but gaps in knowledge and trust remain. Thanks to brilliant coauthors @amynmalik @saadomer3

Tuberculosis preventive treatment for household contacts at health facility and community settings in Pakistan ✅ Just Accepted ✍️ @amynmalik 🔗 https://t.co/cIvCjfdR6p

Are pan-TB treatment regimens likely to drive the emergence of novel drug resistance? We investigated, in a new paper here https://t.co/XkFr0o1sMv with @emilyakendall @NickMenzies2 @richardwhite321 @ted_h_cohen @rycktessman @LSHTM @LSHTM_TB @cmmid_lshtm @lshtm_tbmod

@CFMcQuaid @IRDGlobal @LSHTM @TBMAC @TB_MAC #contacttracing #tuberculosis

Household contacts of not tested patients are not contact traced resulting in missed opportunities for early diagnosis & transmission prevention. Expanding contact tracing strategies under such conditions can improve diagnosis. However, studies are needed to establish feasibility

However, this is what happens in programmatic settings and the aim of this work was to evaluate contact tracing strategies under programmatic conditions. Not all patients are tested in such conditions.

One criticism of the work is that not all index patients were tested microbiologically. Thus the results may be because of similar transmission by "truly' clinically diagnosed patients or because of bacteriologically positive patients misclassified as clinically diagnosed.

Most TB programs focus on a subset of household contacts for contact management leaving many contacts unscreened. We show that the yield from tracing contacts of guidelines ineligible patients is similar to guidelines eligible patients. @utswosph https://t.co/w0cTj0KNRy

A massive effort led by @LaurenPischel and team. The VE of 2 dose MVA-BN is 82% against Mpox. https://t.co/czI23PEzNi #medtwitter #epidemiology @utswosph

Amazing work! This paper provides a nuanced analysis of who benefits the most from TPT and in what context. Fortunate to work with an amazing team on this. #medtwitter @utswosph

Had a great time at the @union_tblh NAR and @tbcontrollers meeting in Baltimore this week. Always a pleasure running into old friends, meeting new friends, and introducing new trainees to our welcoming community. @tiara_boston @BUSPH #endTB

Thank you @s_keshavjee for the wonderful talk!

On this #WorldTBDay2024, join us at @utswosph for a talk by @s_keshavjee on TB Elimination: Challenges, Barriers, and Gaps. What can we do differently? @StopTB @harvardmed

Our individual patient data meta-analysis shows levofloxacin exposures at current WHO-recommended doses is below the AUC target for children. Revised weight-band dosing guidelines of >20 mg/kg required. @utswosph @IRDGlobal #MedTwitter #GlobalHealth https://t.co/W2fGejxEfh

When someone talks about limited real world evidence for a particular intervention and how they intend to fill that gap, but you have published on it multiple times (with ~15k participants in 1 instance) including the same comparison they are making #MedTwitter #conferences

New study from #Pakistan #Wastewater sampling effectively predicts an outbreak of #COVID19 in areas with low active case surveillance or poor access to care, even without a well-mapped sewage system Read more 👉 https://t.co/QlTm4LCW2E

Our SARS-CoV-2 environmental surveillance study is now published in The Lancet Regional Health-Southeast Asia! Read how our brilliant lab, bioinformatics and stats teams correlated SARS-COV-2 RNA conc. with reported cases in the 'sewershed': https://t.co/YMMVg9H11q @imran_nisar

Improving the quality of the Global Burden of Disease tuberculosis estimates from the Institute for Health Metrics and Evaluation https://t.co/eF8QRDMPDx